Search Results - "Goringer, U"
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Trypanosoma brucei TBRGG1, a mitochondrial oligo(U)-binding protein that co-localizes with an in vitro RNA editing activity
Published in The Journal of biological chemistry (21-08-1998)“…We report the characterization of a Trypanosoma brucei 75-kDa protein of the RGG (Arg-Gly-Gly) type, termed TBRGG1. Dicistronic and monocistronic transcripts…”
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Combinatorial selection of high affinity RNA ligands to live African trypanosomes
Published in Nucleic acids research (01-05-1999)“…African trypanosomiasis is a parasitic disease caused by a specific class of protozoan organisms. The best-studied representative of that group is Trypanosoma…”
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3
Mutant 16S Ribosomal RNA: A Codon-Specific Translational Suppressor
Published in Proceedings of the National Academy of Sciences - PNAS (01-06-1988)“…We have isolated an unusual codon-specific translational suppressor in Escherichia coli. The suppressor resulted from a spontaneous mutation in a chromosomal…”
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Influence of the GCGC discriminator motif introduced into the ribosomal RNA P2‐ and tac promoter on growth‐rate control and stringent sensitivity
Published in The EMBO journal (01-11-1989)“…The synthesis of stable RNA in bacteria is known to be regulated by a stringent control mechanism. Characteristic of stringent‐regulated promoters, all…”
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Analysis of the Fis-dependent and Fis-independent transcription activation mechanisms of the Escherichia coli ribosomal RNA P1 promoter
Published in Biochemistry (Easton) (10-03-1992)“…The role of the curved DNA sequence upstream to the Escherichia coli ribosomal RNA P1 promoter in transcription activation was studied. This sequence region…”
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The guide RNA database
Published in Nucleic acids research (01-01-1998)“…Guide RNAs (gRNAs) are small, metabolically stable RNA molecules which perform a pivotal, template-like function during the RNA editing process in…”
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Disruption of a gene encoding a novel mitochondrial DEAD-box protein in Trypanosoma brucei affects edited mRNAs
Published in Molecular and Cellular Biology (01-09-1997)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Annealing of RNA editing substrates facilitated by guide RNA-binding protein gBP21
Published in The EMBO journal (15-03-2001)“…RNA editing within the mitochondria of African trypanosomes is characterized by the insertion and deletion of uridylate residues into otherwise incomplete…”
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Uptake and intracellular transport of RNA Aptamers in African trypanosomes suggest therapeutic “Piggy-Back” approach
Published in Bioorganic & medicinal chemistry (01-10-2001)“…African trypanosomes are protozoan organisms that multiply as extracellular parasites in the blood of humans and other mammals. The parasites escape…”
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Assembly of mitochondrial ribonucleoprotein complexes involves specific guide RNA (gRNA)-binding proteins and gRNA domains but does not require preedited mRNA
Published in Molecular and Cellular Biology (01-04-1994)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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11
The formation of mitochondrial ribonucleoprotein complexes involving guide RNA molecules in Trypanosoma brucei
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1994)“…Transcripts from mitochondrial (maxicircle) genes of kinetoplastid organisms undergo RNA editing characterized by a series of reactions that insert and delete…”
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12
A three-dimensional working model for a guide RNA from Trypanosoma brucei
Published in Nucleic acids research (15-06-1997)“…RNA editing in protozoan parasites is a mitochondrial RNA processing reaction in which exclusively uridylate residues are inserted into, and less frequently…”
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Trypanosoma brucei mitochondrial ribonucleoprotein complexes which contain 12S and 9S ribosomal RNAs
Published in Parasitology (01-02-1998)“…Antibiotics have been widely used to identify ribosomal activity in Trypanosoma brucei mitochondria. The validity of some of the results has been questioned…”
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The guide RNA database (3.0)
Published in Nucleic acids research (1999)“…The RNA editing process within the mitochondria of kinetoplastid organisms is controlled by small, trans-acting RNA molecules referred to as guide RNAs. the…”
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In vitro synthesized small interfering RNAs elicit RNA interference in african trypanosomes: an in vitro and in vivo analysis
Published in The Journal of biological chemistry (27-05-2005)“…RNA interference (RNAi) describes an epigenetic gene silencing reaction by which gene-specific double-stranded RNA acts as a trigger to induce the…”
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RNA aptamers as potential pharmaceuticals against infections with African trypanosomes
Published in Handbook of experimental pharmacology (2006)“…Protozoal pathogens cause symptomatic as well as asymptomatic infections. They have a worldwide impact, which in part is reflected in the long-standing search…”
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DEAD-box protein HEL64 from Trypanosoma brucei : subcellular localization and gene knockout analysis
Published in Parasitology research (1987) (01-04-1999)“…RNA helicases are molecules that play a central role in the control of ribonucleic acid metabolism. Only two putative RNA helicase genes of the DEAD-box family…”
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Multicomponent complexes involved in kinetoplastid RNA editing
Published in Parasitology today (Regular ed.) (1995)“…Several genes in trypanosomatic mitochondria require RNA editing for their expression. Although the reaction mechanism as well as the editing machinery have…”
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guide RNA database
Published in Nucleic acids research (1997)“…The RNA editing process in protozoan parasites is controlled by small RNA molecules known as guide RNAs (gRNAs). The gRNA database is a comprehensive…”
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TbMP42 is a structure-sensitive ribonuclease that likely follows a metal ion catalysis mechanism
Published in Nucleic acids research (01-08-2008)“…RNA editing in African trypanosomes is characterized by a uridylate-specific insertion and/or deletion reaction that generates functional mitochondrial…”
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