Search Results - "Goring, H"

The lipidome in major depressive disorder: Shared genetic influence for ether-phosphatidylcholines, a plasma-based phenotype related to inflammation, and disease risk by Knowles, E.E.M, Huynh, K, Meikle, P.J, Göring, H.H.H, Olvera, R.L, Mathias, S.R, Duggirala, R, Almasy, L, Blangero, J, Curran, J.E, Glahn, D.C

“…Abstract Background The lipidome is rapidly garnering interest in the field of psychiatry. Recent studies have implicated lipidomic changes across numerous…”
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Vitamin D deficiency in Europeans today and in Viking settlers of Greenland by Göring, H., Koshuchowa, S.

“…The vast majority of the Earth’s population lives between the 20th and 40th parallel north and south. It seems that right here humans have found the best…”
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High Dimensional Endophenotype Ranking in the Search for Major Depression Risk Genes by Glahn, David C, Curran, Joanne E, Winkler, Anderson M, Carless, Melanie A, Kent, Jack W, Charlesworth, Jac C, Johnson, Matthew P, Göring, Harald H.H, Cole, Shelley A, Dyer, Thomas D, Moses, Eric K, Olvera, Rene L, Kochunov, Peter, Duggirala, Ravi, Fox, Peter T, Almasy, Laura, Blangero, John

“…Background Despite overwhelming evidence that major depression is highly heritable, recent studies have localized only a single depression-related locus…”
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A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5 by Sigurdsson, Snaevar, Nordmark, Gunnel, Garnier, Sophie, Grundberg, Elin, Kwan, Tony, Nilsson, Olof, Eloranta, Maija-Leena, Gunnarsson, Iva, Svenungsson, Elisabet, Sturfelt, Gunnar, Bengtsson, Anders A., Jönsen, Andreas, Truedsson, Lennart, Rantapää-Dahlqvist, Solbritt, Eriksson, Catharina, Alm, Gunnar, Göring, Harald H.H., Pastinen, Tomi, Syvänen, Ann-Christine, Rönnblom, Lars

“…Systemic lupus erythematosus (SLE) is the prototype autoimmune disease where genes regulated by type I interferon (IFN) are over-expressed and contribute to…”
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Genz and Mendell-Elston Estimation of the High-Dimensional Multivariate Normal Distribution by Blondell, Lucy, Kos, Mark Z., Blangero, John, Göring, Harald H. H.

“…Statistical analysis of multinomial data in complex datasets often requires estimation of the multivariate normal (mvn) distribution for models in which the…”
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Whole Genome Sequence Data From Captive Baboons Implicate RBFOX1 in Epileptic Seizure Risk by Kos, Mark Z., Carless, Melanie A., Blondell, Lucy, Leland, M. Michelle, Knape, Koyle D., Göring, Harald H. H., Szabó, Charles Ákos

“…In this study, we investigate the genetic determinants that underlie epilepsy in a captive baboon pedigree and evaluate the potential suitability of this…”
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Genome-wide linkage scan for loci of musical aptitude in Finnish families: evidence for a major locus at 4q22 by Pulli, K, Karma, K, Norio, R, Sistonen, P, Göring, H H H, Järvelä, I

“…Music perception and performance are comprehensive human cognitive functions and thus provide an excellent model system for studying human behaviour and brain…”
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Neurocognitive impairment in type 2 diabetes: evidence for shared genetic aetiology by Mollon, Josephine, Curran, Joanne E., Mathias, Samuel R., Knowles, Emma E. M., Carlisle, Phoebe, Fox, Peter T., Olvera, Rene L., Göring, Harald H. H., Rodrigue, Amanda, Almasy, Laura, Duggirala, Ravi, Blangero, John, Glahn, David C.

“…Aims/hypothesis Type 2 diabetes is associated with cognitive impairments, but it is unclear whether common genetic factors influence both type 2 diabetes risk…”
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Genome-wide linkage on chromosome 10q26 for a dimensional scale of major depression by Knowles, Emma E.M, Kent, Jack W, McKay, D. Reese, Sprooten, Emma, Mathias, Samuel R, Curran, Joanne E, Carless, Melanie A, de Almeida, Marcio A.A, Harald, H.H. Goring, Dyer, Tom D, Olvera, Rene L, Fox, Peter T, Duggirala, Ravi, Almasy, Laura, Blangero, John, Glahn, David C

“…Abstract Major depressive disorder (MDD) is a common and potentially life-threatening mood disorder. Identifying genetic markers for depression might provide…”
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Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs by Zhang, Xiaoling, Gierman, Hinco J, Levy, Daniel, Plump, Andrew, Dobrin, Radu, Goring, Harald H H, Curran, Joanne E, Johnson, Matthew P, Blangero, John, Kim, Stuart K, O'Donnell, Christopher J, Emilsson, Valur, Johnson, Andrew D

“…Gene expression genetic studies in human tissues and cells identify cis- and trans-acting expression quantitative trait loci (eQTLs). These eQTLs provide…”
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Vitamin D — the sun hormone. Life in environmental mismatch by Göring, H., Koshuchowa, S.

“…While some representatives of the animal kingdom were improving their biological mechanisms and properties for adapting to ever-changing life conditions, the…”
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The genetic basis of the comorbidity between cannabis use and major depression by Hodgson, Karen, Almasy, Laura, Knowles, Emma E. M., Kent, Jack W., Curran, Joanne E., Dyer, Thomas D., Göring, Harald H. H., Olvera, Rene L., Woolsey, Mary D., Duggirala, Ravi, Fox, Peter T., Blangero, John, Glahn, David C.

“…Background and aims While the prevalence of major depression is elevated among cannabis users, the role of genetics in this pattern of comorbidity is not…”
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Cocktail-party listening and cognitive abilities show strong pleiotropy by Mathias, Samuel R, Knowles, Emma E M, Mollon, Josephine, Rodrigue, Amanda L, Woolsey, Mary K, Hernandez, Alyssa M, Garret, Amy S, Fox, Peter T, Olvera, Rene L, Peralta, Juan M, Kumar, Satish, Göring, Harald H H, Duggirala, Ravi, Curran, Joanne E, Blangero, John, Glahn, David C

“…The cocktail-party problem refers to the difficulty listeners face when trying to attend to relevant sounds that are mixed with irrelevant ones. Previous…”
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Genotype phasing in pedigrees using whole-genome sequence data by Blackburn, August N, Blondell, Lucy, Kos, Mark Z, Blackburn, Nicholas B, Peralta, Juan M, Stevens, Peter T, Lehman, Donna M, Blangero, John, Göring, Harald H H

“…Phasing is the process of inferring haplotypes from genotype data. Efficient algorithms and associated software for accurate phasing in pedigrees are needed,…”
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Chemerin, a Novel Adipokine in the Regulation of Angiogenesis by Bozaoglu, Kiymet, Curran, Joanne E., Stocker, Claire J., Zaibi, Mohamed S., Segal, David, Konstantopoulos, Nicky, Morrison, Shona, Carless, Melanie, Dyer, Thomas D., Cole, Shelley A., Goring, Harald H. H., Moses, Eric K., Walder, Ken, Cawthorne, Michael A., Blangero, John, Jowett, Jeremy B. M.

“…Context: Chemerin is a new adipokine associated with obesity and the metabolic syndrome. Gene expression levels of chemerin were elevated in the adipose depots…”
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Genome-wide association scan identifies a risk locus for preeclampsia on 2q14, near the inhibin, beta B gene by Johnson, Matthew P, Brennecke, Shaun P, East, Christine E, Göring, Harald H H, Kent, Jr, Jack W, Dyer, Thomas D, Said, Joanne M, Roten, Linda T, Iversen, Ann-Charlotte, Abraham, Lawrence J, Heinonen, Seppo, Kajantie, Eero, Kere, Juha, Kivinen, Katja, Pouta, Anneli, Laivuori, Hannele, Austgulen, Rigmor, Blangero, John, Moses, Eric K

“…Elucidating the genetic architecture of preeclampsia is a major goal in obstetric medicine. We have performed a genome-wide association study (GWAS) for…”
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Disentangling the genetic overlap between cholesterol and suicide risk by Knowles, Emma E M, Curran, Joanne E, Meikle, Peter J, Huynh, Kevin, Mathias, Samuel R, Göring, Harald H H, VandeBerg, John L, Mahaney, Michael C, Jalbrzikowski, Maria, Mosior, Marian K, Michael, Laura F, Olvera, Rene L, Duggirala, Ravi, Almasy, Laura, Glahn, David C, Blangero, John

“…Suicide is major public health concern; one million individuals worldwide die by suicide each year of which there are many more attempts. Thus, it is…”
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Shared Genetic Factors Influence Head Motion During MRI and Body Mass Index by Hodgson, Karen, Poldrack, Russell A, Curran, Joanne E, Knowles, Emma E, Mathias, Samuel, Göring, Harald H H, Yao, Nailin, Olvera, Rene L, Fox, Peter T, Almasy, Laura, Duggirala, Ravi, Barch, Deanna M, Blangero, John, Glahn, David C

“…Head movements are typically viewed as a nuisance to functional magnetic resonance imaging (fMRI) analysis, and are particularly problematic for resting state…”
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Transcriptomics of cortical gray matter thickness decline during normal aging by Kochunov, P., Charlesworth, J., Winkler, A., Hong, L.E., Nichols, T.E., Curran, J.E., Sprooten, E., Jahanshad, N., Thompson, P.M., Johnson, M.P., Kent, J.W., Landman, B.A., Mitchell, B., Cole, S.A., Dyer, T.D., Moses, E.K., Goring, H.H.H., Almasy, L., Duggirala, R., Olvera, R.L., Glahn, D.C., Blangero, J.

“…We performed a whole-transcriptome correlation analysis, followed by the pathway enrichment and testing of innate immune response pathway analyses to evaluate…”
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Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation by Hsueh, Wen-Chi, Nair, Anup K, Kobes, Sayuko, Chen, Peng, Göring, Harald H H, Pollin, Toni I, Malhotra, Alka, Knowler, William C, Baier, Leslie J, Hanson, Robert L

“…Identity-by-descent mapping using empirical estimates of identity-by-descent allele sharing may be useful for studies of complex traits in founder populations,…”
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