Search Results - "Gorgogietas, Vyron"
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Boswellic acids and their derivatives as potent regulators of glucocorticoid receptor actions
Published in Archives of biochemistry and biophysics (30-11-2020)“…Glucocorticoid (GCs) hormones exert their actions via their cognate steroid receptors the Glucocorticoid Receptors (GR), by genomic or non-genomic mechanisms…”
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Neurotoxic effects of aluminum are associated with its interference with estrogen receptors signaling
Published in Neurotoxicology (Park Forest South) (01-03-2020)“…•Aluminum chlorohydrate induces reduction in ERβ protein levels in SH-SY5Y cells.•Aluminum chlorohydrate causes increase in ERα protein levels in SH-SY5Y…”
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The triterpene echinocystic acid and its 3-O-glucoside derivative are revealed as potent and selective glucocorticoid receptor agonists
Published in The international journal of biochemistry & cell biology (01-10-2016)“…•Prediction of glucocorticoid receptor-echinocytic acids binding via molecular docking.•Echinocystic acids induce glucocorticoid receptor nuclear…”
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Biochemical and biological assessment of the inhibitory potency of extracts from vinification byproducts of Vitis vinifera extracts against glycogen phosphorylase
Published in Food and chemical toxicology (01-05-2014)“…[Display omitted] •Antidiabetic potency of 13 polyphenolic extracts from vinification byproducts of Greek varieties of Vitis vinifera assessed.•All extract…”
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The In Vitro Impact of the Herbicide Roundup on Human Sperm Motility and Sperm Mitochondria
Published in Toxics (Basel) (21-12-2017)“…Toxicants, such as herbicides, have been hypothesized to affect sperm parameters. The most common method of exposure to herbicides is through spraying or diet…”
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Molecular mechanisms of β-cell dysfunction and death in monogenic forms of diabetes
Published in International review of cell and molecular biology (2021)“…Monogenetic forms of diabetes represent 1%-5% of all diabetes cases and are caused by mutations in a single gene. These mutations, that affect genes involved…”
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Proteomic analysis of the mitochondrial glucocorticoid receptor interacting proteins reveals pyruvate dehydrogenase and mitochondrial 60 kDa heat shock protein as potent binding partners
Published in Journal of proteomics (15-04-2022)“…Glucocorticoids are steroid hormones that regulate plethora biological actions such as growth and metabolism, immune response, and apoptosis. Glucocorticoids…”
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GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models
Published in Diabetologia (01-07-2023)“…Aims/hypothesis Wolfram syndrome is a rare autosomal recessive disorder caused by pathogenic variants in the WFS1 gene. It is characterised by…”
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