Search Results - "Gorenne, Isabelle"

Vascular Smooth Muscle Cell Sirtuin 1 Protects Against DNA Damage and Inhibits Atherosclerosis by GORENNE, Isabelle, KUMAR, Sheetal, GRAY, Kelly, FIGG, Nichola, HAIXIANG YU, MERCER, John, BENNETT, Martin

“…Vascular smooth muscle cells (VSMCs) in human atherosclerosis manifest extensive DNA damage and activation of the DNA damage response, a pathway that…”
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DNA Damage Links Mitochondrial Dysfunction to Atherosclerosis and the Metabolic Syndrome by Mercer, John R, Cheng, Kian-Kai, Figg, Nichola, Gorenne, Isabelle, Mahmoudi, Melli, Griffin, Julian, Vidal-Puig, Antonio, Logan, Angela, Murphy, Michael P, Bennett, Martin

“…RATIONALE:DNA damage is present in both genomic and mitochondrial DNA in atherosclerosis. However, whether DNA damage itself promotes atherosclerosis, or is…”
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Mid-term health-related quality of life in community-acquired bacterial meningitis survivors; the COMBAT study by Della Vecchia, Claire, Ebah, Josée Vicentia, Tubiana, Sarah, Guimard, Thomas, Piroth, Lionel, Jaffuel, Sylvain, Gorenne, Isabelle, Mourvillier, Bruno, Hoen, Bruno, Duval, Xavier, Préau, Marie

“…Community Acute Bacterial Meningitis (CABM) is a rare infectious disease leading to important impairments. Our aim was to describe CABM survivors' quality of…”
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Statins Use a Novel Nijmegen Breakage Syndrome-1–Dependent Pathway to Accelerate DNA Repair in Vascular Smooth Muscle Cells by Mahmoudi, Melli, Gorenne, Isabelle, Mercer, John, Figg, Nicola, Littlewood, Trevor, Bennett, Martin

“…Although the hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins) are widely used in atherosclerosis to reduce serum cholesterol, statins have…”
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Reverse Regulatory Pathway (H2S / PGE2 / MMP) in Human Aortic Aneurysm and Saphenous Vein Varicosity by Gomez, Ingrid, Ozen, Gulsev, Deschildre, Catherine, Amgoud, Yasmine, Boubaya, Lilia, Gorenne, Isabelle, Benyahia, Chabha, Roger, Thomas, Lesèche, Guy, Galardon, Erwan, Topal, Gokce, Jacob, Marie-Paule, Longrois, Dan, Norel, Xavier

“…Hydrogen sulfide (H2S) is a mediator with demonstrated protective effects for the cardiovascular system. On the other hand, prostaglandin (PG)E2 is involved in…”
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LPP, a LIM protein highly expressed in smooth muscle by Gorenne, Isabelle, Nakamoto, Robert K, Phelps, Clayton P, Beckerle, Mary C, Somlyo, Avril V, Somlyo, Andrew P

“…An 80-kDa protein, prominently expressed in smooth muscle, was microsequenced and identified as LPP, the product of the lipoma-preferred partner gene (Petit…”
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Vascular Smooth Muscle Cells Undergo Telomere-Based Senescence in Human Atherosclerosis: Effects of Telomerase and Oxidative Stress by Matthews, Charles, Gorenne, Isabelle, Scott, Stephen, Figg, Nicola, Kirkpatrick, Peter, Ritchie, Andrew, Goddard, Martin, Bennett, Martin

“…Although human atherosclerosis is associated with aging, direct evidence of cellular senescence and the mechanism of senescence in vascular smooth muscle cells…”
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Regulation by GDI of RhoA/Rho-kinase-induced Ca2+ sensitization of smooth muscle myosin II by Gong, M C, Gorenne, I, Read, P, Jia, T, Nakamoto, R K, Somlyo, A V, Somlyo, A P

“…We characterized the role of guanine nucleotide dissociation inhibitor (GDI) in RhoA/Rho-kinase-mediated Ca2+ sensitization of smooth muscle. Endogenous…”
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Vascular smooth muscle cell senescence in atherosclerosis by GORENNE, Isabelle, KAVURMA, Mary, SCOTT, Stephen, BENNETT, Martin

“…Markers of cell senescence have been identified in both the blood and vessel wall of patients with atherosclerosis. In particular, vascular smooth muscle cells…”
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Sera Neutralizing Activities Against Severe Acute Respiratory Syndrome Coronavirus 2 and Multiple Variants 6 Months After Hospitalization for Coronavirus Disease 2019 by Betton, Maureen, Livrozet, Marine, Planas, Delphine, Fayol, Antoine, Monel, Blandine, Védie, Benoit, Bruel, Timothée, Tartour, Eric, Robillard, Nicolas, Manuguerra, Jean-Claude, Blanchard, Anne, Ghosn, Jade, Visseaux, Benoit, Péré, Hélène, Lebeaux, David, Schwartz, Olivier, Veyer, David, Hulot, Jean-Sébastien, Abel, Laurent, Andrejak, Claire, Angoulvant, François, Bachelet, Delphine, Bhavsar, Krishna, Bouadma, Lila, Chair, Anissa, Couffignal, Camille, da Silveira, Charlene, Debray, Marie-Pierre, Descamps, Diane, Duval, Xavier, Eloy, Philippine, Esposito-Farese, Marina, Ettalhaoui, Nadia, Gault, Nathalie, Ghosn, Jade, Gorenne, Isabelle, Hoffmann, Isabelle, Kafif, Ouifiya, Kali, Sabrina, Khalil, Antoine, Laouénan, Cédric, Laribi, Samira, Le, Minh, Le Hingrat, Quentin, Lescure, François-Xavier, Lucet, Jean Christophe, Mentré, France, Mullaert, Jimmy, Peiffer-Smadja, Nathan, Peytavin, Gilles, Roy, Carine, Schneider, Marion, Si Mohammed, Nassima, Tagherset, Lysa, Tardivon, Coralie, Tellier, Marie-Capucine, Timsit, Jean-François, Trioux, Théo, Tubiana, Sarah, Visseaux, Benoit, Yazdanpanah, Yazdan, Basmaci, Romain, Picone, Olivier, Behilill, Sylvie, van der Werf, Sylvie, Enouf, Vincent, Mouquet, Hugo, Beluze, Marine, Benkerrou, Dehbia, Dorival, Céline, Téoulé, François, Meziane, Amina, Bompart, François, Bouscambert, Maude, Cervantes-Gonzalez, Minerva, d’Ortenzio, Eric, Puéchal, Oriane, Semaille, Caroline, Chirouze, Catherine, Coelho, Alexandra, Couffin-Cadiergues, Sandrine, Esperou, Hélène, Houas, Ikram, Jaafoura, Salma, Papadopoulos, Aurélie, Deplanque, Dominique, Desvallée, Mathilde, Khan, Coralie, Diallo, Alpha, Bartoli, Marie, Le Mestre, Soizic, Mercier, Noémie, Paul, Christelle, Petrov-Sanchez, Ventzislava, Diouf, Alphonsine, Hoctin, Alexandre, Mambert, Marina, Dubos, François, Etienne, Manuel, Gaymard, Alexandre

“…Abstract Background Humoral response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurs within the first weeks after coronavirus disease…”
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Impact on disease mortality of clinical, biological, and virological characteristics at hospital admission and overtime in COVID‐19 patients by Yazdanpanah, Yazdan

“…Little is known on the association between clinical factors and coronavirus disease 2019 (COVID‐19) more than 15 days after diagnosis. We conducted a…”
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Mid-term health-related quality of life in community-acquired bacterial meningitis survivors; the COMBAT study by Claire Della Vecchia, Josée Vicentia Ebah, Sarah Tubiana, Thomas Guimard, Lionel Piroth, Sylvain Jaffuel, Isabelle Gorenne, Bruno Mourvillier, Bruno Hoen, Xavier Duval, Marie Préau

“…Background Community Acute Bacterial Meningitis (CABM) is a rare infectious disease leading to important impairments. Our aim was to describe CABM survivors’…”
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Sodium hydrosulfite contractions of smooth muscle are calcium and myosin phosphorylation independent by Yu, M F, Gorenne, I, Su, X, Moreland, R S, Kotlikoff, M I

“…In an effort to further understand the processes underlying hypoxic pulmonary vasoconstriction, we examined the mechanism by which sodium hydrosulfite…”
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Relationship between serotypes, disease characteristics and 30-day mortality in adults with invasive pneumococcal disease by Benadji, Amine, Duval, Xavier, Danis, Kostas, Hoen, Bruno, Page, Bernard, Béraud, Guillaume, Vernet-Garnier, Véronique, Strady, Christophe, Brieu, Nathalie, Maulin, Laurence, Roy, Carine, Ploy, Marie-Cécile, Gaillat, Jacques, Varon, Emmanuelle, Tubiana, Sarah

“…Purpose Invasive pneumococcal disease (IPD) is responsible for substantial mortality and morbidity worldwide. We aimed to identify host and bacterial factors…”
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Leukocyte Telomere Length Is Associated With High-Risk Plaques on Virtual Histology Intravascular Ultrasound and Increased Proinflammatory Activity by Calvert, Patrick A, Liew, Tze-Vun, Gorenne, Isabelle, Clarke, Murray, Costopoulos, Charis, Obaid, Daniel R, OʼSullivan, Michael, Shapiro, Leonard M, McNab, Duncan C, Densem, Cameron G, Schofield, Peter M, Braganza, Denise, Clarke, Sarah C, Ray, Kausik K, West, Nick E.J, Bennett, Martin R

“…OBJECTIVE—Leukocyte telomere length (LTL), a marker of cellular senescence, is inversely associated with cardiovascular events. However, whether LTL reflects…”
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Reverse Regulatory Pathway by Gomez, Ingrid, Ozen, Gulsev, Deschildre, Catherine, Amgoud, Yasmine, Boubaya, Lilia, Gorenne, Isabelle, Benyahia, Chabha, Roger, Thomas, Lesèche, Guy, Galardon, Erwan, Topal, Gokce, Jacob, Marie-Paule, Longrois, Dan, Norel, Xavier

“…Hydrogen sulfide (H.sub.2 S) is a mediator with demonstrated protective effects for the cardiovascular system. On the other hand, prostaglandin (PG)E.sub.2 is…”
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Sirtuin 1 deficiency promotes DNA damage in vascular smooth muscle cells and aggravates atherosclerosis by Kumar, Sheetal, Yu, Haixiang, Figg, Nichola, Mercer, John, Bennett, Martin R, Gorenne, Isabelle

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Abstract 780: Atorvastatin Activates A Novel Nbs1-dependent Mechanism Of Accelerating Dna Repair In Atherosclerosis by Mahmoudi, Melli M, Gorenne, Isabelle C, Mercer, John R, Figg, Nichola L, Bennett, Martin R

“…Abstract only There is increasing evidence that reactive oxidant species (ROS) and DNA damage promote the development and complications of atherosclerosis…”
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Caldesmon phosphorylation is catalyzed by two kinases in permeabilized and intact vascular smooth muscle by Gorenne, Isabelle, Su, Xiaoling, Moreland, Robert S.

“…Smooth muscle contraction is initiated by myosin light chain (MLC) phosphorylation catalyzed by the Ca2+ dependent MLC kinase. However, many aspects of smooth…”
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Inhibition of p42 and p44 MAP kinase does not alter smooth muscle contraction in swine carotid artery by Gorenne, I, Su, X, Moreland, R S

“…Caldesmon inhibits myosin ATPase activity; phosphorylation of caldesmon reverses the inhibition. The caldesmon kinase is believed to be mitogen-activated…”
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