Search Results - "Gorelov, Alexander"

Macromolecular Crowding Meets Tissue Engineering by Self-Assembly: A Paradigm Shift in Regenerative Medicine by Satyam, Abhigyan, Kumar, Pramod, Fan, Xingliang, Gorelov, Alexander, Rochev, Yury, Joshi, Lokesh, Peinado, Héctor, Lyden, David, Thomas, Benjamin, Rodriguez, Brian, Raghunath, Michael, Pandit, Abhay, Zeugolis, Dimitrios

“…MMC, the addition of inert polydispersed macromolecules in the culture media, effectively emulates the dense in vivo extracellular space, resulting in…”
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Film Thickness Determines Cell Growth and Cell Sheet Detachment from Spin-Coated Poly(N‑Isopropylacrylamide) Substrates by Dzhoyashvili, Nina A, Thompson, Kerry, Gorelov, Alexander V, Rochev, Yuri A

“…Poly­(N-isopropylacrylamide) (pNIPAm) is widely used to fabricate thermoresponsive surfaces for cell sheet detachment. Many complex and expensive techniques…”
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Macromolecularly crowded in vitro microenvironments accelerate the production of extracellular matrix-rich supramolecular assemblies by Kumar, Pramod, Satyam, Abhigyan, Fan, Xingliang, Collin, Estelle, Rochev, Yury, Rodriguez, Brian J., Gorelov, Alexander, Dillon, Simon, Joshi, Lokesh, Raghunath, Michael, Pandit, Abhay, Zeugolis, Dimitrios I.

“…Therapeutic strategies based on the principles of tissue engineering by self-assembly put forward the notion that functional regeneration can be achieved by…”
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Accelerated Development of Supramolecular Corneal Stromal-Like Assemblies from Corneal Fibroblasts in the Presence of Macromolecular Crowders by Kumar, Pramod, Satyam, Abhigyan, Fan, Xingliang, Rochev, Yury, Rodriguez, Brian J, Gorelov, Alexander, Joshi, Lokesh, Raghunath, Michael, Pandit, Abhay, Zeugolis, Dimitrios I

“…Tissue engineering by self-assembly uses the cells' secretome as a regeneration template and biological factory of trophic factors. Despite the several…”
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Straightforward, One-Step Fabrication of Ultrathin Thermoresponsive Films from Commercially Available pNIPAm for Cell Culture and Recovery by Nash, Maria E, Carroll, William M, Nikoloskya, Natalia, Yang, Rongbing, Connell, Claire O′, Gorelov, Alexander V, Dockery, Peter, Liptrot, Catherine, Lyng, Fiona M, Garcia, Amaya, Rochev, Yury A

“…The use of thermoresponsive surfaces as platforms for cell culture and cell regeneration has been explored over the last couple of decades…”
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Thermoresponsive Substrates Used for the Growth and Controlled Differentiation of Human Mesenchymal Stem Cells by Fan, Xingliang, Nash, Maria E., Gorelov, Alexander V., Barry, Frank P., Shaw, Georgina, Rochev, Yury A.

“…This communication outlines the advances made in the development of thermoresponsive substrates for human mesenchymal stem cell (hMSC) expansion and subsequent…”
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An implantable thermoresponsive drug delivery system based on Peltier device by Yang, Rongbing, Gorelov, Alexander V., Aldabbagh, Fawaz, Carroll, William M., Rochev, Yury

“…Locally dropping the temperature in vivo is the main obstacle to the clinical use of a thermoresponsive drug delivery system. In this paper, a Peltier…”
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The management of acute diarrhea in children in developed and developing areas: from evidence base to clinical practice by Guarino, Alfredo, Dupont, Christophe, Gorelov, Alexander V, Gottrand, Frederic, Lee, Jimmy K F, Lin, Zhihong, Lo Vecchio, Andrea, Nguyen, Thien D, Salazar-Lindo, Eduardo

“…Acute diarrhea remains a major problem in children and is associated with substantial morbidity, mortality and costs. While vaccination against rotavirus could…”
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Thermoresponsive Substrates used for the Expansion of Human Mesenchymal Stem Cells and the Preservation of Immunophenotype by Nash, Maria E., Fan, Xingliang, Carroll, William M., Gorelov, Alexander V., Barry, Frank P., Shaw, Georgina, Rochev, Yury A.

“…The facile regeneration of undifferentiated human mesenchymal stem cells (hMSCs) from thermoresponsive surfaces facilitates the collection of stem cells…”
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Synthesis and characterization of a novel thermoresponsive copolymer series and their application in cell and cell sheet regeneration by Nash, Maria E., Carroll, William M., Velasco, Diego, Gomez, Javier, Gorelov, Alexander V., Elezov, Dmitry, Gallardo, Alberto, Rochev, Yury A., Elvira, Carlos

“…A series of poly-(N-isopropyl acrylamide)-based copolymers were developed with a view to biomedical applications, specifically cell cultivation and recovery…”
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Thermoresponsive Poly(N-isopropylacrylamide) Copolymers:  Contact Angles and Surface Energies of Polymer Films by Gilcreest, Vincent P, Carroll, William M, Rochev, Yuri A, Blute, Irena, Dawson, Kenneth A, Gorelov, Alexander V

“…Surface properties of poly(N-isopropylacrylamide) (PNIPAM) copolymer films were studied by contact angle measurements and optical and atomic force microscopy…”
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Cell growth and detachment from protein-coated PNIPAAm-based copolymers by Moran, Martin T., Carroll, William M., Selezneva, Irina, Gorelov, Alexander, Rochev, Yuri

“…The cultivation of cells requires the use of unfavorable proteolytic enzymes, which cause cell‐surface modification and also need considerable optimization…”
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A mathematical model for pulsatile release: Controlled release of rhodamine B from UV-crosslinked thermoresponsive thin films by Yang, Rongbing, Vo T. N., Tuoi, Gorelov, Alexander V., Aldabbagh, Fawaz, Carroll, William M., Meere, Martin G., Rochev, Yury

“…A controlled drug delivery system fabricated from a thermoresponsive polymer was designed to obtain a pulsatile release profile which was triggered by altering…”
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Intact endothelial cell sheet harvesting from thermoresponsive surfaces coated with cell adhesion promoters by Moran, Martin T, Carroll, William M, Gorelov, Alexander, Rochev, Yuri

“…-isopropylacrylamide) (PNIPAAm). However, this requires expensive techniques to generate a sufficiently thin film that allows cell adhesion. In this study, we…”
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Adsorption Kinetics of NIPAM-Based Polymers at the Air−Water Interface As Studied by Pendant Drop and Bubble Tensiometry by Gilcreest, Vincent P, Dawson, Kenneth A, Gorelov, Alexander V

“…The adsorption of N-isopropylacrylamide (NIPAM) based thermoresponsive polymers at the air−water interface was investigated by using drop and bubble shape…”
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Measuring the Micro-Polarity and Hydrogen-Bond Donor/Acceptor Ability of Thermoresponsive N-Isopropylacrylamide/N-tert-Butylacrylamide Copolymer Films Using Solvatochromic Indicators by Szczupak, Boguslaw, Ryder, Alan G., Togashi, Denisio M., Rochev, Yuri A., Gorelov, Alexander V., Glynn, Thomas J.

“…Thin polymer films are important in many areas of biomaterials research, biomedical devices, and biological sensors. The accurate in situ measurement of…”
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Poly( N-isopropylacrylamide) co-polymer films as potential vehicles for delivery of an antimitotic agent to vascular smooth muscle cells by Doorty, Kevina B., Golubeva, Tatiana A., Gorelov, Alexander V., Rochev, Yuri A., Allen, Lorcan T., Dawson, Kenneth A., Gallagher, William M., Keenan, Alan K.

“…Introduction: Local delivery of antimitotic agents is a potential therapeutic strategy for protection of injured coronary vasculature against intimal…”
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Complex formation between DNA and cationic surfactant by Gorelov, Alexander V., Kudryashov, Evgeny D., Jacquier, Jean-Christophe, McLoughlin, Daragh M., Dawson, Kenneth A.

“…Complex formation between short DNA fragments and dodecyltrimethylammonium bromide (DoTAB) has been studied using dynamic (DLS), static light scattering (SLS),…”
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Macromolecular crowding transforms regenerative medicine by enabling the accelerated development of functional and truly three-dimensional cell assembled micro tissues by De Pieri, Andrea, Korntner, Stefanie H., Capella-Monsonis, Hector, Tsiapalis, Dimitrios, Kostjuk, Sergei V., Churbanov, Semyon, Timashev, Peter, Gorelov, Alexander, Rochev, Yuri, Zeugolis, Dimitrios I.

“…Scaffold-free in vitro organogenesis exploits the innate ability of cells to synthesise and deposit their own extracellular matrix to fabricate tissue-like…”
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Fermented Milk Consumption and Common Infections in Children Attending Day-Care Centers: A Randomized Trial by Prodeus, Andrey, Niborski, Violeta, Schrezenmeir, Juergen, Gorelov, Alexander, Shcherbina, Anna, Rumyantsev, Alexander

“…OBJECTIVES:This multicenter, double-blind, randomized, placebo-controlled clinical trial investigated the effect of a fermented milk product containing the…”
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