Search Results - "Gorelkin, Petr"

Novel Pumping Methods for Microfluidic Devices: A Comprehensive Review by Iakovlev, Aleksei P, Erofeev, Alexander S, Gorelkin, Petr V

“…This review is an account of methods that use various strategies to control microfluidic flow control with high accuracy. The reviewed systems are divided into…”
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Pt(IV) Prodrugs with Non-Steroidal Anti-inflammatory Drugs in the Axial Position by Spector, Daniil V., Pavlov, Kirill G., Akasov, Roman A., Vaneev, Alexander N., Erofeev, Alexander S., Gorelkin, Petr V., Nikitina, Vita N., Lopatukhina, Elena V., Semkina, Alevtina S., Vlasova, Kseniya Yu, Skvortsov, Dmitrii A., Roznyatovsky, Vitaly A., Ul’yanovskiy, Nikolay V., Pikovskoi, Ilya I., Sypalov, Sergey A., Garanina, Anastasiia S., Vodopyanov, Stepan S., Abakumov, Maxim A., Volodina, Yulia L., Markova, Alina A., Petrova, Albina S., Mazur, Dmitrii M., Sakharov, Dmitry A., Zyk, Nikolay V., Beloglazkina, Elena K., Majouga, Alexander G., Krasnovskaya, Olga O.

“…We report herein the design, synthesis, and biological investigation of a series of novel Pt­(IV) prodrugs with non-steroidal anti-inflammatory drugs naproxen,…”
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Electrochemical Nanoprobes for Single-Cell Analysis by Actis, Paolo, Tokar, Sergiy, Clausmeyer, Jan, Babakinejad, Babak, Mikhaleva, Sofya, Cornut, Renaud, Takahashi, Yasufumi, López Córdoba, Ainara, Novak, Pavel, Shevchuck, Andrew I, Dougan, Jennifer A, Kazarian, Sergei G, Gorelkin, Petr V, Erofeev, Alexander S, Yaminsky, Igor V, Unwin, Patrick R, Schuhmann, Wolfgang, Klenerman, David, Rusakov, Dmitri A, Sviderskaya, Elena V, Korchev, Yuri E

“…The measurement of key molecules in individual cells with minimal disruption to the biological milieu is the next frontier in single-cell analyses. Nanoscale…”
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Electrochemical Detection of a Novel Pt(IV) Prodrug with the Metronidazole Axial Ligand in the Hypoxic Area by Spector, Daniil V., Erofeev, Alexander S., Gorelkin, Petr V., Vaneev, Alexander N., Akasov, Roman A., Ul’yanovskiy, Nikolay V., Nikitina, Vita N., Semkina, Alevtina S., Vlasova, Kseniya Yu, Soldatov, Mikhail A., Trigub, Alexander L., Skvortsov, Dmitry A., Finko, Alexander V., Zyk, Nikolay V., Sakharov, Dmitry A., Majouga, Alexander G., Beloglazkina, Elena K., Krasnovskaya, Olga O.

“…We report herein a Pt­(IV) prodrug with metronidazole in axial positions Pt-Mnz. The nitroaromatic axial ligand was conjugated with a cisplatin scaffold to…”
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Mapping mechanical properties of living cells at nanoscale using intrinsic nanopipette-sample force interactions by Kolmogorov, Vasilii S, Erofeev, Alexander S, Woodcock, Emily, Efremov, Yuri M, Iakovlev, Aleksei P, Savin, Nikita A, Alova, Anna V, Lavrushkina, Svetlana V, Kireev, Igor I, Prelovskaya, Alexandra O, Sviderskaya, Elena V, Scaini, Denis, Klyachko, Natalia L, Timashev, Peter S, Takahashi, Yasufumi, Salikhov, Sergey V, Parkhomenko, Yuri N, Majouga, Alexander G, Edwards, Christopher R W, Novak, Pavel, Korchev, Yuri E, Gorelkin, Petr V

“…Mechanical properties of living cells determined by cytoskeletal elements play a crucial role in a wide range of biological functions. However, low-stress…”
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Changes in ROS/RNS Levels in Endothelial Cells in Experimental Bacteremia by Pleskova, Svetlana N., Vaneev, Alexander N., Bezrukov, Nikolay A., Erofeev, Alexander S., Bobyk, Sergey Z., Kolmogorov, Vasilii S., Gorelkin, Petr V., Mamed‐Nabizade, Vugara V., Gorshkova, Ekaterina N.

“…A high‐precision system was developed for the quantification of biological analytes in single cells (reactive oxygen species (ROS) and reactive nitrogen…”
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Synthesis and Biological Evaluation of PSMA Ligands with Aromatic Residues and Fluorescent Conjugates Based on Them by Machulkin, Aleksei E, Shafikov, Radik R, Uspenskaya, Anastasia A, Petrov, Stanislav A, Ber, Anton P, Skvortsov, Dmitry A, Nimenko, Ekaterina A, Zyk, Nikolay U, Smirnova, Galina B, Pokrovsky, Vadim S, Abakumov, Maxim A, Saltykova, Irina V, Akhmirov, Rauf T, Garanina, Anastasiia S, Polshakov, Vladimir I, Saveliev, Oleg Y, Ivanenkov, Yan A, Aladinskaya, Anastasiya V, Finko, Alexander V, Yamansarov, Emil U, Krasnovskaya, Olga O, Erofeev, Alexander S, Gorelkin, Petr V, Dontsova, Olga A, Beloglazkina, Elena K, Zyk, Nikolay V, Khazanova, Elena S, Majouga, Alexander G

“…Prostate-specific membrane antigen (PSMA), also known as glutamate carboxypeptidase II (GCPII), is a suitable target for specific delivery of antitumor drugs…”
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Novel Copper-Containing Cytotoxic Agents Based on 2‑Thioxoimidazolones by Krasnovskaya, Olga O, Guk, Dmitry A, Naumov, Alexey E, Nikitina, Vita N, Semkina, Alevtina S, Vlasova, Kseniya Yu, Pokrovsky, Vadim, Ryabaya, Oksana O, Karshieva, Saida S, Skvortsov, Dmitry A, Zhirkina, Irina V, Shafikov, Radik R, Gorelkin, Petr V, Vaneev, Alexander N, Erofeev, Alexander S, Mazur, Dmitrii M, Tafeenko, Viktor A, Pergushov, Vladimir I, Melnikov, Mikhail Ya, Soldatov, Mikhail A, Shapovalov, Victor V, Soldatov, Alexander V, Akasov, Roman. A, Gerasimov, Vasily M, Sakharov, Dmitry A, Moiseeva, Anna A, Zyk, Nikolay V, Beloglazkina, Elena K, Majouga, Alexander G

“…A series of 73 ligands and 73 of their Cu+2 and Cu+1 copper complexes with different geometries, oxidation states of the metal, and redox activities were…”
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In Vitro and In Vivo Electrochemical Measurement of Reactive Oxygen Species After Treatment with Anticancer Drugs by Vaneev, Alexander N, Gorelkin, Petr V, Garanina, Anastasiia S, Lopatukhina, Helena V, Vodopyanov, Stepan S, Alova, Anna V, Ryabaya, Oxana O, Akasov, Roman A, Zhang, Yanjun, Novak, Pavel, Salikhov, Sergey V, Abakumov, Maxim A, Takahashi, Yasufumi, Edwards, Christopher R W, Klyachko, Natalia L, Majouga, Alexander G, Korchev, Yuri E, Erofeev, Alexander S

“…monitoring of reactive oxygen species (ROS) in tumors during treatment with anticancer therapy is important for understanding the mechanism of action and in…”
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PSMA-targeted small-molecule docetaxel conjugate: Synthesis and preclinical evaluation by Machulkin, Aleksei E., Uspenskaya, Anastasia A., Zyk, Nikolay Y., Nimenko, Ekaterina A., Ber, Anton P., Petrov, Stanislav A., Shafikov, Radik R., Skvortsov, Dmitry A., Smirnova, Galina B., Borisova, Yulia A., Pokrovsky, Vadim S., Kolmogorov, Vasilii S., Vaneev, Alexander N., Ivanenkov, Yan A., Khudyakov, Alexander D., Kovalev, Sergei V., Erofeev, Alexander S., Gorelkin, Petr V., Beloglazkina, Elena K., Zyk, Nikolay V., Khazanova, Elena S., Majouga, Alexander G.

“…Prostate cancer is one of the most commonly diagnosed men's cancers and remains one of the leading causes of cancer death. The development of approaches to the…”
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New Small-Molecule Glycoconjugates of Docetaxel and GalNAc for Targeted Delivery to Hepatocellular Carcinoma by Petrov, Rostislav A, Mefedova, Sofiia R, Yamansarov, Emil Yu, Maklakova, Svetlana Yu, Grishin, Dmitrii A, Lopatukhina, Elena V, Burenina, Olga Y, Lopukhov, Anton V, Kovalev, Sergey V, Timchenko, Yury V, Ondar, Evgenia E, Ivanenkov, Yan A, Evteev, Sergei A, Vaneev, Alexander N, Timoshenko, Roman V, Klyachko, Natalia L, Erofeev, Alexander S, Gorelkin, Petr V, Beloglazkina, Elena K, Majouga, Alexander G

“…In this work, we have developed covalent and low molecular weight docetaxel delivery systems based on conjugation with -acetyl-d-galactosamine and studied…”
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Discovery of Bivalent GalNAc-Conjugated Betulin as a Potent ASGPR-Directed Agent against Hepatocellular Carcinoma by Yamansarov, Emil Yu, Lopatukhina, Elena V, Evteev, Sergei A, Skvortsov, Dmitry A, Lopukhov, Anton V, Kovalev, Sergey V, Vaneev, Alexander N, Shkil’, Dmitry O, Akasov, Roman A, Lobov, Alexander N, Naumenko, Victor A, Pavlova, Ekaterina N, Ryabaya, Oxana O, Burenina, Olga Yu, Ivanenkov, Yan A, Klyachko, Natalia L, Erofeev, Alexander S, Gorelkin, Petr V, Beloglazkina, Elena K, Majouga, Alexander G

“…Herein, we describe the design, synthesis, and biological evaluation of novel betulin and N-acetyl-d-galactosamine (GalNAc) glycoconjugates and suggest them as…”
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Nano- and Microsensors for In Vivo Real-Time Electrochemical Analysis: Present and Future Perspectives by Vaneev, Alexander N, Timoshenko, Roman V, Gorelkin, Petr V, Klyachko, Natalia L, Korchev, Yuri E, Erofeev, Alexander S

“…Electrochemical nano- and microsensors have been a useful tool for measuring different analytes because of their small size, sensitivity, and favorable…”
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Analytical Models for Measuring the Mechanical Properties of Yeast by Savin, Nikita, Erofeev, Alexander, Gorelkin, Petr

“…The mechanical properties of yeast play an important role in many biological processes, such as cell division and growth, maintenance of internal pressure, and…”
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Electrochemical Nanopipette Sensor for In Vitro/In Vivo Detection of Cu2+ Ions by Timoshenko, Roman V., Gorelkin, Petr V., Vaneev, Alexander N., Krasnovskaya, Olga O., Akasov, Roman A., Garanina, Anastasiia S., Khochenkov, Dmitry A., Iakimova, Tamara M., Klyachko, Natalia L., Abakumova, Tatiana O., Shashkovskaya, Vera S., Chaprov, Kirill D., Makarov, Alexander A., Mitkevich, Vladimir A., Takahashi, Yasufumi, Edwards, Christopher R. W., Korchev, Yuri E., Erofeev, Alexander S.

“…In vitro/in vivo detection of copper ions is a challenging task but one which is important in the development of new approaches to the diagnosis and treatment…”
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Scanning Ion-Conductance Microscopy for Studying β‑Amyloid Aggregate Formation on Living Cell Surfaces by Kolmogorov, Vasilii S., Erofeev, Alexander S., Barykin, Evgeny P., Timoshenko, Roman V., Lopatukhina, Elena V., Kozin, Sergey A., Gorbacheva, Lyubov R., Salikhov, Sergey V., Klyachko, Natalia L., Mitkevich, Vladimir A., Edwards, Christopher R. W., Korchev, Yuri E., Makarov, Alexander A., Gorelkin, Petr V.

“…β-Amyloid aggregation on living cell surfaces is described as responsible for the neurotoxicity associated with different neurodegenerative diseases. It is…”
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In Vitro/In Vivo Electrochemical Detection of Pt(II) Species by Vaneev, Alexander N, Gorelkin, Petr V, Krasnovskaya, Olga O, Akasov, Roman A, Spector, Daniil V, Lopatukhina, Elena V, Timoshenko, Roman V, Garanina, Anastasiia S, Zhang, Yanjun, Salikhov, Sergey V, Edwards, Christopher R. W, Klyachko, Natalia L, Takahashi, Yasufumi, Majouga, Alexander G, Korchev, Yuri E, Erofeev, Alexander S

“…The biodistribution of chemotherapy compounds within tumor tissue is one of the main challenges in the development of antineoplastic drugs, and techniques for…”
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Label-free sensitive detection of influenza virus using PZT discs with a synthetic sialylglycopolymer receptor layer by Erofeev, Alexander S, Gorelkin, Petr V, Kolesov, Dmitry V, Kiselev, Gleb A, Dubrovin, Evgeniy V, Yaminsky, Igor V

“…We describe rapid, label-free detection of Influenza A viruses using the first radial mode of oscillations of lead zirconate titanate (PZT) piezoelectric discs…”
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Electrochemical Nanopipette Sensor for In Vitro/In Vivo Detection of Cu 2+ Ions by Timoshenko, Roman V, Gorelkin, Petr V, Vaneev, Alexander N, Krasnovskaya, Olga O, Akasov, Roman A, Garanina, Anastasiia S, Khochenkov, Dmitry A, Iakimova, Tamara M, Klyachko, Natalia L, Abakumova, Tatiana O, Shashkovskaya, Vera S, Chaprov, Kirill D, Makarov, Alexander A, Mitkevich, Vladimir A, Takahashi, Yasufumi, Edwards, Christopher R W, Korchev, Yuri E, Erofeev, Alexander S

“…In vitro/in vivo detection of copper ions is a challenging task but one which is important in the development of new approaches to the diagnosis and treatment…”
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Photoinduced Reduction of Novel Dual-Action Riboplatin Pt(IV) Prodrug by Krasnovskaya, Olga O., Akasov, Roman A., Spector, Daniil V., Pavlov, Kirill G., Bubley, Anna A., Kuzmin, Vladimir A., Kostyukov, Alexey A., Khaydukov, Evgeny V., Lopatukhina, Elena V., Semkina, Alevtina S., Vlasova, Kseniya Yu, Sypalov, Sergey A., Erofeev, Alexander S., Gorelkin, Petr V., Vaneev, Alexander N., Nikitina, Vita N., Skvortsov, Dmitrii A., Ipatova, Daria A., Mazur, Dmitrii M., Zyk, Nikolay V., Sakharov, Dmitry A., Majouga, Alexander G., Beloglazkina, Elena K.

“…Controlled photoreduction of Pt­(IV) prodrugs is a challenging task due to the possibility of targeted light-controlled activation of anticancer agents without…”
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