Search Results - "Gore, Sayali"

Novel use of FDA-approved drugs identified by cluster analysis of behavioral profiles by Tucker Edmister, Sara, Del Rosario Hernández, Thaís, Ibrahim, Rahma, Brown, Cameron A., Gore, Sayali V., Kakodkar, Rohit, Kreiling, Jill A., Creton, Robbert

“…Repurposing FDA-approved drugs is an efficient and cost-effective approach in the development of therapeutics for a broad range of diseases. However,…”
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Zebrafish Larvae Position Tracker (Z-LaP Tracker): a high-throughput deep-learning behavioral approach for the identification of calcineurin pathway-modulating drugs using zebrafish larvae by Gore, Sayali V., Kakodkar, Rohit, Del Rosario Hernández, Thaís, Edmister, Sara Tucker, Creton, Robbert

“…Brain function studies greatly depend on quantification and analysis of behavior. While behavior can be imaged efficiently, the quantification of specific…”
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Behavioral effects of visual stimuli in adult zebrafish using a novel eight-tank imaging system by Gore, Sayali V, Del Rosario Hernández, Thaís, Creton, Robbert

“…Animals respond to various environmental cues. Animal behavior is complex, and behavior analysis can greatly help to understand brain function. Most of the…”
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Drug repurposing for neurodegenerative diseases using Zebrafish behavioral profiles by Del Rosario Hernández, Thaís, Gore, Sayali V., Kreiling, Jill A., Creton, Robbert

“…Drug repurposing can accelerate drug development while reducing the cost and risk of toxicity typically associated with de novo drug design. Several disorders…”
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An 8-cage imaging system for automated analyses of mouse behavior by Del Rosario Hernández, Thaís, Joshi, Narendra R., Gore, Sayali V., Kreiling, Jill A., Creton, Robbert

“…The analysis of mouse behavior is used in biomedical research to study brain function in health and disease. Well-established rapid assays allow for…”
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Role of matrix metalloproteinase-9 in neurodevelopmental deficits and experience-dependent plasticity in Xenopus laevis by Gore, Sayali V, James, Eric J, Huang, Lin-chien, Park, Jenn J, Berghella, Andrea, Thompson, Adrian C, Cline, Hollis T, Aizenman, Carlos D

“…Matrix metalloproteinase-9 (MMP-9) is a secreted endopeptidase targeting extracellular matrix proteins, creating permissive environments for neuronal…”
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Synthetic cathinones and their phenethylamine analogues produce distinct psychomotor and reward behavior in crayfish by Gore, Sayali, van Staaden, Moira J., Sprague, Jon E., Huber, Robert

“…[Display omitted] •Synthetic cathinones and phenethylamine analogues produce psychostimulation in crayfish.•Repeated drug doses increase the duration of…”
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Drug-sensitive Reward in Crayfish: Exploring the Neural Basis of Addiction with Automated Learning Paradigms by Huber, Robert, Imeh-Nathaniel, Adebobola, Nathaniel, Thomas I., Gore, Sayali, Datta, Udita, Bhimani, Rohan, Panksepp, Jules B., Panksepp, Jaak, van Staaden, Moira J.

“…Systemic infusions into the pericardial cavity (A) or drug delivery in close proximity to the supraesophageal ganglion (B) accessory lobes (enlarged in C)…”
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