Search Results - "Gore, Emilia"

Transcriptomic characterization of culture-associated changes in murine and human precision-cut tissue slices by Bigaeva, Emilia, Gore, Emilia, Simon, Eric, Zwick, Matthias, Oldenburger, Anouk, de Jong, Koert P., Hofker, Hendrik S., Schlepütz, Marco, Nicklin, Paul, Boersema, Miriam, Rippmann, Jörg F., Olinga, Peter

“…Our knowledge of complex pathological mechanisms underlying organ fibrosis is predominantly derived from animal studies. However, relevance of animal models…”
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Osteoprotegerin Expression in Liver is Induced by IL13 through TGFβ by Adhyatmika, Adhyatmika, Putri, Kurnia S S, Gore, Emilia, Mangnus, Keri A, Reker-Smit, Catharina, Schuppan, Detlef, Beljaars, Leonie, Olinga, Peter, Melgert, Barbro N

“…Osteoprotegerin (OPG) is a profibrotic mediator produced by myofibro-blasts under influence of transforming growth factor β (TGFβ). Its expression in…”
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Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices by Vatakuti, Suresh, Pennings, Jeroen L. A, Gore, Emilia, Olinga, Peter, Groothuis, Geny M. M

“…Human toxicity screening is an important stage in the development of safe drug candidates. Hepatotoxicity is one of the major reasons for the withdrawal of…”
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PI3K inhibition reduces murine and human liver fibrogenesis in precision-cut liver slices by Gore, Emilia, Bigaeva, Emilia, Oldenburger, Anouk, Kim, Yong Ook, Rippmann, Jörg F., Schuppan, Detlef, Boersema, Miriam, Olinga, Peter

“…[Display omitted] Liver fibrosis results from continuous inflammation and injury. Despite its high prevalence worldwide, no approved antifibrotic therapies…”
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P2Y13 receptor deficiency favors adipose tissues lipolysis and worsens insulin resistance and fatty liver disease by Duparc, Thibaut, Gore, Emilia, Combes, Guillaume, Beuzelin, Diane, Da Silva, Julie Pires, Bouguetoch, Vanessa, Marquès, Marie-Adeline, Velazquez, Ana, Viguerie, Nathalie, Tavernier, Geneviève, Arner, Peter, Rydén, Mikael, Langin, Dominique, Sioufi, Nabil, Cabou, Cendrine, Najib, Souad, Martinez, Laurent

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Investigating fibrosis and inflammation in an ex vivo NASH murine model by Gore, Emilia, Bigaeva, Emilia, Oldenburger, Anouk, Jansen, Yvette J M, Schuppan, Detlef, Boersema, Miriam, Rippmann, Jörg F, Broermann, Andre, Olinga, Peter

“…Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease, characterized by excess fat accumulation (steatosis). Nonalcoholic steatohepatitis…”
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Exploring organ-specific features of fibrogenesis using murine precision-cut tissue slices by Bigaeva, Emilia, Gore, Emilia, Mutsaers, Henricus A.M., Oosterhuis, Dorenda, Kim, Yong Ook, Schuppan, Detlef, Bank, Ruud A., Boersema, Miriam, Olinga, Peter

“…Fibrosis is the hallmark of pathologic tissue remodelling in most chronic diseases. Despite advances in our understanding of the mechanisms of fibrosis, it…”
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Sa1554 - PI3K/MTOR Pathway Inhibition in EX-VIVO Liver Model by Gore, Emilia, Bigaeva, Emilia, Boersema, Miriam, Nicklin, Paul, Schuppan, Detlef, Olinga, Peter

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PI3K/MTOR Pathway Inhibition in EX - VIVO Liver Model by Gore, Emilia, Bigaeva, Emilia, Boersema, Miriam, Nicklin, Paul, Schuppan, Detlef, Olinga, Peter

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187 Deletion of IL-4Ra on Macrophages Renders Mice Resistant to Intestinal Inflammation by Pickert, Geethanjali, Gore, Emilia, Brombacher, Frank, Schuppan, Detlef

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Mo1271 Wheat Alpha-Amylase/Trypsin Inhibitors Are Strong Activators of Innate Immunity in Murine and Human Intestinal Tissue Explants by Zevallos, Victor F, Pham, Bao Tung, Oosterhuis, Dorenda, Gore, Emilia, Jansen, Esmee, Olinga, Peter, Schuppan, Detlef

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P2Y13 receptor deficiency favors adipose tissues lipolysis and worsens insulin resistance and fatty liver disease by Duparc, Thibaut, Gore, Emilia, Combes, Guillaume, Beuzelin, Diane, Pires Da Silva, Julie, Bouguetoch, Vanessa, Marquès, Marie-Adeline, Velazquez, Ana, Viguerie, Nathalie, Tavernier, Geneviève, Arner, Peter, Rydén, Mikael, Langin, Dominique, Sioufi, Nabil, Nasser, Mohamad, Cabou, Cendrine, Najib, Souad, Martinez, Laurent O

“…Excessive lipolysis in white adipose tissues (WAT) leads to insulin resistance (IR) and ectopic fat accumulation in insulin-sensitive tissues. However, the…”
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P2Y13 receptor deficiency favors adipose tissue lipolysis and worsens insulin resistance and fatty liver disease by Duparc, Thibaut, Gore, Emilia, Combes, Guillaume, Beuzelin, Diane, Pires Da Silva, Julie, Bouguetoch, Vanessa, Marquès, Marie-Adeline, Velazquez, Ana, Viguerie, Nathalie, Tavernier, Geneviève, Arner, Peter, Rydén, Mikael, Langin, Dominique, Sioufi, Nabil, Nasser, Mohamad, Cabou, Cendrine, Najib, Souad, Martinez, Laurent O.

“…Excessive lipolysis in white adipose tissue (WAT) leads to insulin resistance (IR) and ectopic fat accumulation in insulin-sensitive tissues. However, the…”
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