Search Results - "Gordon, Victor"

Chronic stress and intestinal barrier dysfunction: Glucocorticoid receptor and transcription repressor HES1 regulate tight junction protein Claudin-1 promoter by Zheng, Gen, Victor Fon, Gordon, Meixner, Walter, Creekmore, Amy, Zong, Ye, K. Dame, Michael, Colacino, Justin, Dedhia, Priya H., Hong, Shuangsong, Wiley, John W.

“…Chronic stress and elevated glucocorticoid hormone are associated with decreases in the intestinal epithelial tight junction protein claudin-1 (CLDN1)…”
Get full text

3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification by Kalinin, Alexandr A., Allyn-Feuer, Ari, Ade, Alex, Fon, Gordon-Victor, Meixner, Walter, Dilworth, David, Husain, Syed S., de Wet, Jeffrey R., Higgins, Gerald A., Zheng, Gen, Creekmore, Amy, Wiley, John W., Verdone, James E., Veltri, Robert W., Pienta, Kenneth J., Coffey, Donald S., Athey, Brian D., Dinov, Ivo D.

“…Quantitative analysis of morphological changes in a cell nucleus is important for the understanding of nuclear architecture and its relationship with…”
Get full text

Valproic acid-induced changes of 4D nuclear morphology in astrocyte cells by Kalinin, Alexandr A, Hou, Xinhai, Ade, Alex S, Fon, Gordon-Victor, Meixner, Walter, Higgins, Gerald A, Sexton, Jonathan Z, Wan, Xiang, Dinov, Ivo D, O'Meara, Matthew J, Athey, Brian D

“…Histone deacetylase inhibitors, such as valproic acid (VPA), have important clinical therapeutic and cellular reprogramming applications. They induce chromatin…”
Get full text

A Single TCF Transcription Factor, Regardless of Its Activation Capacity, Is Sufficient for Effective Trilineage Differentiation of ESCs by Moreira, Steven, Polena, Enio, Gordon, Victor, Abdulla, Solen, Mahendram, Sujeivan, Cao, Jiayi, Blais, Alexandre, Wood, Geoffrey A., Dvorkin-Gheva, Anna, Doble, Bradley W.

“…Co-expression and cross-regulation of the four TCF/LEFs render their redundant and unique functions ambiguous. Here, we describe quadruple-knockout (QKO) mouse…”
Get full text

RapidAI Compared With Human Readers of Acute Stroke Imaging for Detection of Intracranial Vessel Occlusion by Slater, Lee‐Anne, Ravintharan, Nandhini, Goergen, Stacy, Chandra, Ronil, Asadi, Hamed, Maingard, Julian, Kuganesan, Ahilan, Sum, Reuben, Lin, Sandra, Gordon, Victor, Rajendran, Deepa, Lie, Yenni, Muthusamy, Subramanian, Kempster, Peter, Phan, Thanh G.

“…Background Rapid detection of intracranial arterial occlusion in patients with ischemic stroke is important to facilitate timely reperfusion therapy. We…”
Get full text

Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression by Zagozewski, Jamie, Borlase, Stephanie, Guppy, Brent J., Coudière-Morrison, Ludivine, Shahriary, Ghazaleh M., Gordon, Victor, Liang, Lisa, Cheng, Stephen, Porter, Christopher J., Kelley, Rhonda, Hawkins, Cynthia, Chan, Jennifer A., Liang, Yan, Gong, Jingjing, Nör, Carolina, Saulnier, Olivier, Wechsler-Reya, Robert J., Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra E.

“…Medulloblastoma (MB) is the most common primary malignant pediatric brain cancer. We recently identified novel roles for the MEK/MAPK pathway in regulating…”
Get full text

Publisher Correction: 3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification by Kalinin, Alexandr A., Allyn-Feuer, Ari, Ade, Alex, Fon, Gordon-Victor, Meixner, Walter, Dilworth, David, Husain, Syed S., de Wet, Jeffrey R., Higgins, Gerald A., Zheng, Gen, Creekmore, Amy, Wiley, John W., Verdone, James E., Veltri, Robert W., Pienta, Kenneth J., Coffey, Donald S., Athey, Brian D., Dinov, Ivo D.

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
Get full text

Modified two-stage basilic vein transposition for hemodialysis access by Paulson, Kari A., M.D, Gordon, Victor, B.S, Flynn, Lisa, M.D., F.A.C.S., R.V.T, Lorelli, David, M.D., F.A.C.S., R.V.T

“…Abstract Background Various techniques for basilic vein transposition have been described, including endovascular, 1-stage, and 2-stage transposition. However,…”
Get full text

3D Cell Nuclear Morphology: Microscopy Imaging Dataset and Voxel-Based Morphometry Classification Results by Kalinin, Alexandr A., Allyn-Feuer, Ari, Ade, Alex, Fon, Gordon-Victor, Meixner, Walter, Dilworth, David, de Wet, Jeffrey R., Higgins, Gerald A., Zheng, Gen, Creekmore, Amy, Wiley, John W., Verdone, James E., Veltri, Robert W., Pienta, Kenneth J., Coffey, Donald S., Athey, Brian D., Dinov, Ivo D.

“…Cell deformation is regulated by complex underlying biological mechanisms associated with spatial and temporal morphological changes in the nucleus that are…”
Get full text

Failure of human rhombic lip differentiation underlies medulloblastoma formation by Hendrikse, Liam D., Haldipur, Parthiv, Saulnier, Olivier, Millman, Jake, Erickson, Anders W., Gordon, Victor, Coudière-Morrison, Ludivine, Shokouhian, Mohammad, Suárez, Raúl A., Ly, Michelle, Borlase, Stephanie, Scott, David S., Farooq, Hamza, Sirbu, Olga, Nambu, Shohei, Funakoshi, Yusuke, Diaz-Mejia, J. Javier, Golser, Joseph, Bach, Kathleen, Phuong-Bao, Tram, Skowron, Patryk, Wang, Evan Y., Kumar, Sachin A., Balin, Polina, Visvanathan, Abhirami, Lee, John J. Y., Ayoub, Ramy, Mungall, Karen L., Wang, Yu C., Kim, Seung-Ki, Bourdeaut, Franck, Doz, François, Masliah-Planchon, Julien, Grajkowska, Wieslawa A., Loukides, James, Dirks, Peter, Fèvre-Montange, Michelle, French, Pim J., Kros, Johan M., Zitterbart, Karel, Bailey, Swneke D., Eberhart, Charles G., Rao, Amulya A. N., Giannini, Caterina, Olson, James M., Phillips, Joanna J., Ra, Young S., de Torres, Carmen, Mora, Jaume, Li, Kay K. W., Poon, Wai S., Pollack, Ian F., López-Aguilar, Enrique, Gillespie, G. Yancey, Shofuda, Tomoko, Vibhakar, Rajeev, Thompson, Reid C., Rubin, Joshua B., Jung, Shin, Lach, Boleslaw, Iolascon, Achille, Ferrucci, Veronica, Zollo, Massimo, Cinalli, Giuseppe, Robinson, Shenandoah, Stearns, Duncan S., Van Meir, Erwin G., Porrati, Paola, Massimino, Maura, Carlotti, Carlos G., Faria, Claudia C., Chan, Jennifer A., Aldinger, Kimberly A., Razavi, Ferechte, McLendon, Roger E., Thompson, Eric M., Ansari, Marc, Garre, Maria L., Chico, Fernando, Eguía, Pilar, Morrissy, A. Sorana, Wu, Xiaochong, Daniels, Craig, Rich, Jeremy N., Jones, Steven J. M., Marra, Marco A., Reimand, Jüri, Sorensen, Poul H., Wechsler-Reya, Robert J., Kleinman, Claudia L., Jabado, Nada, Malkin, David, Ayrault, Olivier, Golden, Jeffrey A., Ellison, David W., Doble, Brad, Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra E., Suzuki, Hiromichi, Millen, Kathleen J.

“…Medulloblastoma (MB) comprises a group of heterogeneous paediatric embryonal neoplasms of the hindbrain with strong links to early development of the hindbrain…”
Get full text

A group 3 medulloblastoma stem cell program is maintained by OTX2-mediated alternative splicing by Saulnier, Olivier, Zagozewski, Jamie, Liang, Lisa, Hendrikse, Liam D., Layug, Paul, Gordon, Victor, Aldinger, Kimberly A., Haldipur, Parthiv, Borlase, Stephanie, Coudière-Morrison, Ludivine, Cai, Ting, Martell, Emma, Gonzales, Naomi M., Palidwor, Gareth, Porter, Christopher J., Richard, Stéphane, Sharif, Tanveer, Millen, Kathleen J., Doble, Brad W., Taylor, Michael D., Werbowetski-Ogilvie, Tamra E.

“…OTX2 is a transcription factor and known driver in medulloblastoma (MB), where it is amplified in a subset of tumours and overexpressed in most cases of group…”
Get full text

STEM-09. A GROUP 3 MEDULLOBLASTOMA STEM CELL PROGRAM IS MAINTAINED BY OTX2-MEDIATED ALTERNATIVE SPLICING by Saulnier, Olivier, Zagozewski, Jamie, Liang, Lisa, Hendrikse, Liam, Layug, Paul, Gordon, Victor, Aldinger, Kimberly, Haldipur, Parthiv, Borlase, Stephanie, Coudière-Morrison, Ludivine, Cai, Ting, Martell, Emma, Gonzales, Naomi, Palidwor, Gareth, Porter, Christopher, Richard, Stephane, Sharif, Tanveer, Millen, Kathleen, Doble, Brad, Taylor, Michael, Werbowetski-Ogilvie, Tamra

“…Abstract Group 3 medulloblastomas (MBs) are highly metastatic pediatric brain tumors with limited therapeutic options. The transcription factor orthodenticle…”
Get full text

Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes by Pekayvaz, Kami, Losert, Corinna, Knottenberg, Viktoria, Gold, Christoph, van Blokland, Irene V., Oelen, Roy, Groot, Hilde E., Benjamins, Jan Walter, Brambs, Sophia, Kaiser, Rainer, Gottschlich, Adrian, Hoffmann, Gordon Victor, Eivers, Luke, Martinez-Navarro, Alejandro, Bruns, Nils, Stiller, Susanne, Akgöl, Sezer, Yue, Keyang, Polewka, Vivien, Escaig, Raphael, Joppich, Markus, Janjic, Aleksandar, Popp, Oliver, Kobold, Sebastian, Petzold, Tobias, Zimmer, Ralf, Enard, Wolfgang, Saar, Kathrin, Mertins, Philipp, Huebner, Norbert, van der Harst, Pim, Franke, Lude H., van der Wijst, Monique G. P., Massberg, Steffen, Heinig, Matthias, Nicolai, Leo, Stark, Konstantin

“…Acute and chronic coronary syndromes (ACS and CCS) are leading causes of mortality. Inflammation is considered a key pathogenic driver of these diseases, but…”
Get full text

MDB-06. ALTERNATIVE SPLICING MEDIATED BY OTX2 DRIVES THE DEVELOPMENT OF GROUP 3 MEDULLOBLASTOMA by Saulnier, Olivier, Zagozewski, Jamie, Liang, Lisa, Hendrikse, Liam D, Layug, Paul, Gordon, Victor, Aldinger, Kimberly A, Haldipur, Parthiv, Borlase, Stephanie, Coudière-Morrison, Ludivine, Cai, Ting, Martell, Emma, Palidwor, Gareth, Porter, Christopher J, Richard, Stephane, Sharif, Tanveer, Doble, Brad W, Millen, Kathleen J, Taylor, Michael D, Werbowetski-Ogilvie, Tamra E

Get full text

MDB-21. THE OTX2-REGULATED ALTERNATIVE SPLICING LANDSCAPE CONTROLS DIFFERENTIATION AND RECONSTITUTES THE DEVELOPMENTAL ORIGINS OF GROUP 3 MEDULLOBLASTOMA by Saulnier, Olivier, Zagozewski, Jamie, Liang, Lisa, Hendrikse, Liam D, Gordon, Victor, Aldinger, Kimberly A, Haldipur, Parthiv, Borlase, Stephanie, Coudiere-Morrison, Ludivine, Layug, Paul, Cai, Ting, Porter, Christopher J, Richard, Stephane, Doble, Brad W, Millen, Kathleen J, Taylor, Michael D, Werbowetski-Ogilvie, Tamra E

“…Abstract Medulloblastoma (MB) is the most common malignant primary pediatric brain tumor with Group 3 MB exhibiting the worst prognosis…”
Get full text

Abstract A81: Investigation of possible cell state dependent differential protein homeostasis mechanism(s) by Fon, Gordon-Victor, Keller, Chandler R., Perlman, David H., Legesse-Miller, Aster

“…Abstract Proteasome inhibition has been shown to be an important strategy for treating many types of cancer. Although proteasome inhibitors are effective at…”
Get full text

Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation by Hendrikse, Liam D., Haldipur, Parthiv, Saulnier, Olivier, Millman, Jake, Erickson, Anders W., Gordon, Victor, Coudière-Morrison, Ludivine, Shokouhian, Mohammad, Suárez, Raúl A., Ly, Michelle, Borlase, Stephanie, Scott, David S., Farooq, Hamza, Sirbu, Olga, Nambu, Shohei, Funakoshi, Yusuke, Diaz-Mejia, J. Javier, Golser, Joseph, Bach, Kathleen, Phuong-Bao, Tram, Skowron, Patryk, Wang, Evan Y., Kumar, Sachin A., Balin, Polina, Visvanathan, Abhirami, Lee, John J. Y., Ayoub, Ramy, Mungall, Karen L., Wang, Yu C., Kim, Seung-Ki, Bourdeaut, Franck, Doz, François, Masliah-Planchon, Julien, Grajkowska, Wieslawa A., Loukides, James, Dirks, Peter, Fèvre-Montange, Michelle, French, Pim J., Kros, Johan M., Zitterbart, Karel, Bailey, Swneke D., Eberhart, Charles G., Rao, Amulya A. N., Giannini, Caterina, Olson, James M., Phillips, Joanna J., Ra, Young S., de Torres, Carmen, Mora, Jaume, Li, Kay K. W., Poon, Wai S., Pollack, Ian F., López-Aguilar, Enrique, Gillespie, G. Yancey, Shofuda, Tomoko, Vibhakar, Rajeev, Thompson, Reid C., Rubin, Joshua B., Jung, Shin, Lach, Boleslaw, Iolascon, Achille, Ferrucci, Veronica, Zollo, Massimo, Cinalli, Giuseppe, Robinson, Shenandoah, Stearns, Duncan S., Van Meir, Erwin G., Porrati, Paola, Massimino, Maura, Carlotti, Carlos G., Faria, Claudia C., Chan, Jennifer A., Aldinger, Kimberly A., Razavi, Ferechte, McLendon, Roger E., Thompson, Eric M., Ansari, Marc, Garre, Maria L., Chico, Fernando, Eguía, Pilar, Morrissy, A. Sorana, Wu, Xiaochong, Daniels, Craig, Rich, Jeremy N., Jones, Steven J. M., Marra, Marco A., Reimand, Jüri, Sorensen, Poul H., Wechsler-Reya, Robert J., Kleinman, Claudia L., Jabado, Nada, Malkin, David, Ayrault, Olivier, Golden, Jeffrey A., Ellison, David W., Doble, Brad, Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra E., Suzuki, Hiromichi, Millen, Kathleen J.

Get full text

Facilitating Frame Injection Exploits through SiK Radio Firmware Modification by WIss, Victor Gordon

“…Many amateur and professional UAS platforms rely on the MAVLink telemetry protocol for UAS command and control and flight telemetry. Oftentimes, this messaging…”
Get full text

Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis by Chan, Derek C.H., Xu, Joshua, Vujovic, Ana, Wong, Nicholas, Gordon, Victor, de Rooij, Laura P.M.H., Moreira, Steven, Joyce, Cailin E., La Rose, Jose, Sandí, María-José, Doble, Bradley W., Novina, Carl D., Rottapel, Robert K., Hope, Kristin J.

“…How hematopoietic stem cells (HSCs) coordinate their divisional axis and whether this orientation is important for stem cell–driven hematopoiesis is poorly…”
Get full text

THE PETROGRAPHY AND ALTERATION OF SOME SPODUMENE PEGMATITES NEAR BEARDMORE, ONTARIO by MILNE, VICTOR GORDON

Get full text