Search Results - "Gordon, Phillip V"

A critical question for NEC researchers: Can we create a consensus definition of NEC that facilitates research progress? by Gordon, Phillip V., MD, PhD, Swanson, Jonathan R., MD, MSc, MacQueen, Brianna C., MD, Christensen, Robert D., MD

“…Abstract In the last decades the reported incidence of preterm necrotizing enterocolitis (NEC) has been declining in large part due to implementing…”
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Necrotizing Enterocolitis in Term Infants by Christensen, Robert D., MD, Lambert, Diane K., RN, Baer, Vickie L., RN, Gordon, Phillip V., MD

“…This article is an overview of NEC in term neonates and also summarizes data from 52 cases within Intermountain Healthcare during the last 11 years. In all 52,…”
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Necrotizing Enterocolitis Among Neonates in the United States by Guthrie, Scott O, Gordon, Phillip V, Thomas, Victor, Thorp, James A, Peabody, Joyce, Clark, Reese H

“…Prior studies have identified individual risk factors that are associated with necrotizing enterocolitis (NEC); however, the small sample sizes of these…”
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Understanding Intestinal Vulnerability to Perforation in the Extremely Low Birth Weight Infant by Gordon, Phillip V

“…Spontaneous intestinal perforation (SIP) occurs commonly in extremely low birth weight (ELBW) infants. Our understanding of its etiologies has improved…”
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A Randomized-Controlled Trial of Prophylactic Hydrocortisone Supplementation for the Prevention of Hypotension in Extremely Low Birth Weight Infants by Efird, Meica M, Heerens, Ann T, Gordon, Phillip V, Bose, Carl L, Young, David A

“…Extremely low birth weight (ELBW) infants are at risk for hypotension. Abnormal adrenal function may play a role in the pathogenesis of hypotension, and…”
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Spontaneous intestinal perforation (SIP) will soon become the most common form of surgical bowel disease in the extremely low birth weight (ELBW) infant by Swanson, Jonathan R., Hair, Amy, Clark, Reese H., Gordon, Phillip V.

“…Recent data have revealed declines in the prevalence rates of NEC over the last decade in premature infants. In contrast, SIP has either remained steady or…”
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Changing the paradigm of defining, detecting, and diagnosing NEC: Perspectives on Bell’s stages and biomarkers for NEC by Gephart, Sheila M., Gordon, Phillip V., Penn, Alexander H., Gregory, Katherine E., Swanson, Jonathan R., Maheshwari, Akhil, Sylvester, Karl

“…Better means to diagnose and define necrotizing enterocolitis are needed to guide clinical practice and research. Adequacy of Bell’s staging system for…”
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Antenatal indomethacin is more likely associated with spontaneous intestinal perforation rather than NEC by Gordon, Phillip V., MD, PhD, Swanson, Jonathan R., MD, Clark, Reese, MD

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Necrotizing Enterocolitis: Using Regulatory Science and Drug Development to Improve Outcomes by Caplan, Michael S., Underwood, Mark A., Modi, Neena, Patel, Ravi, Gordon, Phillip V., Sylvester, Karl G., McElroy, Steven, Manzoni, Paolo, Gephart, Sheila, Chwals, Walter J., Turner, Mark A., Davis, Jonathan M., Allen, Marilee, Baer, Gerri, Besner, Gail, Canvasser, Jennifer, Chaaban, Hala, Clay, Robert, Connolly, Eamonn, Davis, Jonathan M., Duchon, Jennifer, Eklund, Wakako, Ferguson, Joanne, Good, Misty, Grogan, Cristal, Hudson, Lynn, Khashu, Minesh, Kim, Jae, Lotze, Andrea, Mangili, Alexandra, Markel, Troy, Martin, Laura, Miyazawa, Tokuo, Neu, Josef, Noel, Gary, Portman, Ron, Rosito, Simone, Schwartz, Ann, Scottoline, Brian, Seo, Suna, Stromberg, Staffan, Treem, William, Umberger, Erin, Warren, Tracy, West, Alicia

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Necrotizing enterocolitis is one disease with many origins and potential means of prevention by Gordon, Phillip V., Swanson, Jonathan R.

“…The field of necrotizing enterocolitis (NEC) research has been in existence for over 60 years. During the first five decades little progress in NEC prevention…”
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Understanding clinical literature relevant to spontaneous intestinal perforations by Gordon, Phillip V, Attridge, Joshua T

“…Spontaneous intestinal perforation (SIP) has emerged as a disease of extremely low-birth-weight (ELBW) infants over the last two decades. Several risk factors…”
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Hemoperitoneum versus bowel perforation in the extremely low birth weight infant by Kuo, Sheree, Alford, Bennett A., Burns, R. Cartland, Gordon, Phillip V.

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Reopening the Debate on Corticosteroids: To the Editor by Gordon, Phillip V

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A role for plasmin in platelet aggregation: Differential regulation of IGF release from IGF–IGFBP complexes? by Marcinkiewicz, Marek, Gordon, Phillip V

“…Abstract Objectives To determine if plasmin differentially augments platelet aggregation through variable efficiencies of IGF–IGFBP complex cleavage. Methods…”
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An analysis of IGFBP evolution by Gordon, Phillip V, Marcinkiewicz, Marek

“…Abstract Objectives To perform a synonymous, non-synonymous codon mutational analysis of the IGFBP gene family and identify mechanisms by which the IGFBP…”
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A Neonatal Mouse Model of Intestinal Perforation: Investigating the Harmful Synergism Between Glucocorticoids and Indomethacin by Gordon, Phillip V, Herman, Andrew C, Marcinkiewicz, Marek, Gaston, Benjamin M, Laubach, Victor E, Aschner, Judy L

“…ABSTRACT Background: Early postnatal steroids and indomethacin in combination have been shown to increase the risk of spontaneous intestinal perforation (SIP)…”
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Weighing Statistical Certainty Against Ethical, Clinical, and Biologic Expediency: The Contributions of the Watterberg Trial Tip the Scales in the Right Direction by Gordon, Phillip V

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Treatment of Necrotizing Enterocolitis by Gordon, Phillip V

“…To the Editor: The study by Moss et al. (May 25 issue) 1 is impressive because it represents a successful multicenter, prospective, randomized trial…”
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Intestinal Perforations in Very Low Birth Weight Infants: Timing May Be More Important Than You Think by Gordon, Phillip V, Attridge, Joshua T

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A 14-kDa cathepsin L-derived carboxyl IGFBP-2 fragment is sequestered by cultured rat ileal crypt cells by Gordon, Phillip V, Paxton, Jessica B, Kuemmerle, John F, Fox, Nena S

“…IGF-II gut drives mucosal growth during gestation. IGF binding protein-2 (IGFBP-2) has a high affinity for IGF-II and tightly regulates IGF-II availability…”
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