Search Results - "Gordon, Paul M. K."

Transgenic mice overexpressing desmocollin-2 (DSC2) develop cardiomyopathy associated with myocardial inflammation and fibrotic remodeling by Brodehl, Andreas, Belke, Darrell D, Garnett, Lauren, Martens, Kristina, Abdelfatah, Nelly, Rodriguez, Marcela, Diao, Catherine, Chen, Yong-Xiang, Gordon, Paul M K, Nygren, Anders, Gerull, Brenda

“…Arrhythmogenic cardiomyopathy is an inherited heart muscle disorder leading to ventricular arrhythmias and heart failure, mainly as a result of mutations in…”
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Reconstructing SARS-CoV-2 infection dynamics through the phylogenetic inference of unsampled sources of infection by Perera, Deshan, Perks, Ben, Potemkin, Michael, Liu, Andy, Gordon, Paul M K, Gill, M John, Long, Quan, van Marle, Guido

“…The COVID-19 pandemic has illustrated the importance of infection tracking. The role of asymptomatic, undiagnosed individuals in driving infections within this…”
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Characterization of microglial transcriptomes in the brain and spinal cord of mice in early and late experimental autoimmune encephalomyelitis using a RiboTag strategy by Acharjee, Shaona, Gordon, Paul M. K., Lee, Benjamin H., Read, Justin, Workentine, Matthew L., Sharkey, Keith A., Pittman, Quentin J.

“…Microglia play an important role in the pathogenesis of multiple sclerosis and the mouse model of MS, experimental autoimmune encephalomyelitis (EAE). To more…”
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Evaluating the effectiveness of ensemble voting in improving the accuracy of consensus signals produced by various DTWA algorithms from step-current signals generated during nanopore sequencing by Smith, Michael, Chan, Rachel, Khurram, Maaz, Gordon, Paul M K

“…Nanopore sequencing device analysis systems simultaneously generate multiple picoamperage current signals representing the passage of DNA or RNA nucleotides…”
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Glucocorticoid-driven transcriptomes in human airway epithelial cells: commonalities, differences and functional insight from cell lines and primary cells by Mostafa, Mahmoud M, Rider, Christopher F, Shah, Suharsh, Traves, Suzanne L, Gordon, Paul M K, Miller-Larsson, Anna, Leigh, Richard, Newton, Robert

“…Glucocorticoids act on the glucocorticoid receptor (GR; NR3C1) to resolve inflammation and, as inhaled corticosteroids (ICS), are the cornerstone of treatment…”
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Response of the Hyperthermophilic Archaeon Sulfolobus solfataricus to UV Damage by Fröls, Sabrina, Gordon, Paul M K, Panlilio, Mayi Arcellana, Duggin, Iain G, Bell, Stephen D, Sensen, Christoph W, Schleper, Christa

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A shared core microbiome in soda lakes separated by large distances by Zorz, Jackie K., Sharp, Christine, Kleiner, Manuel, Gordon, Paul M. K., Pon, Richard T., Dong, Xiaoli, Strous, Marc

“…In alkaline soda lakes, concentrated dissolved carbonates establish productive phototrophic microbial mats. Here we show how microbial phototrophs and…”
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Gene transcript and metabolite profiling of elicitor-induced opium poppy cell cultures reveals the coordinate regulation of primary and secondary metabolism by Zulak, Katherine G, Cornish, Anthony, Daskalchuk, Timothy E, Deyholos, Michael K, Goodenowe, Dayan B, Gordon, Paul M. K, Klassen, Darren, Pelcher, Lawrence E, Sensen, Christoph W, Facchini, Peter J

“…Elicitor-induced sanguinarine accumulation in opium poppy (Papaver somniferum) cell cultures provides a responsive model system to profile modulations in gene…”
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SnowyOwl: accurate prediction of fungal genes by using RNA-Seq and homology information to select among ab initio models by Reid, Ian, O'Toole, Nicholas, Zabaneh, Omar, Nourzadeh, Reza, Dahdouli, Mahmoud, Abdellateef, Mostafa, Gordon, Paul M K, Soh, Jung, Butler, Gregory, Sensen, Christoph W, Tsang, Adrian

“…Locating the protein-coding genes in novel genomes is essential to understanding and exploiting the genomic information but it is still difficult to accurately…”
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Titin Mutation in Familial Restrictive Cardiomyopathy by Peled, Yael, Gramlich, Michael, Yoskovitz, Guy, Feinberg, Micha S, Afek, Arnon, Polak-Charcon, Sylvie, Pras, Elon, Sela, Ben-Ami, Konen, Eli, Weissbrod, Omer, Geiger, Dan, Gordon, Paul M.K, Thierfelder, Ludwig, Freimark, Dov, Gerull, Brenda, Arad, Michael

“…Abstract Background Familial restrictive cardiomyopathy (RCM) caused by a single gene mutation is the least common of the inherited cardiomyopathies. Only a…”
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Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD): exome sequencing of trios, monozygotic twins and tumours by Barclay, Sarah F, Rand, Casey M, Borch, Lauren A, Nguyen, Lisa, Gray, Paul A, Gibson, William T, Wilson, Richard J A, Gordon, Paul M K, Aung, Zaw, Berry-Kravis, Elizabeth M, Ize-Ludlow, Diego, Weese-Mayer, Debra E, Bech-Hansen, N Torben

“…Rapid-onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD) is thought to be a genetic disease caused by de novo…”
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Osprey: a comprehensive tool employing novel methods for the design of oligonucleotides for DNA sequencing and microarrays by Gordon, Paul M. K., Sensen, Christoph W.

“…We have developed a software package called Osprey for the calculation of optimal oligonucleotides for DNA sequencing and the creation of microarrays based on…”
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Semantic Web Service provision: a realistic framework for Bioinformatics programmers by Gordon, Paul M.K., Trinh, Quang, Sensen, Christoph W.

“…Several semantic Web Services clients for Bioinformatics have been released, but to date no support systems for service providers have been described. We have…”
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Reconstructing the Mosaic Glycolytic Pathway of the Anaerobic Eukaryote Monocercomonoides by Liapounova, Natalia A, Hampl, Vladimir, Gordon, Paul M K, Sensen, Christoph W, Gedamu, Lashitew, Dacks, Joel B

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Stirred suspension bioreactors maintain naïve pluripotency of human pluripotent stem cells by Rohani, Leili, Borys, Breanna S., Razian, Golsa, Naghsh, Pooyan, Liu, Shiying, Johnson, Adiv A., Machiraju, Pranav, Holland, Heidrun, Lewis, Ian A., Groves, Ryan A., Toms, Derek, Gordon, Paul M. K., Li, Joyce W., So, Tania, Dang, Tiffany, Kallos, Michael S., Rancourt, Derrick E.

“…Due to their ability to standardize key physiological parameters, stirred suspension bioreactors can potentially scale the production of quality-controlled…”
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Interspecies data mining to predict novel ING-protein interactions in human by Gordon, Paul M K, Soliman, Mohamed A, Bose, Pinaki, Trinh, Quang, Sensen, Christoph W, Riabowol, Karl

“…The INhibitor of Growth (ING) family of type II tumor suppressors (ING1-ING5) is involved in many cellular processes such as cell aging, apoptosis, DNA repair…”
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Oxford nanopore sequencing in clinical microbiology and infection diagnostics by Sheka, Dropen, Alabi, Nikolay, Gordon, Paul M K

“…Extended turnaround times and large economic costs hinder the usage of currently applied screening methods for bacterial pathogen identification (ID) and…”
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Seahawk: moving beyond HTML in Web-based bioinformatics analysis by Gordon, Paul M K, Sensen, Christoph W

“…Traditional HTML interfaces for input to and output from Bioinformatics analysis on the Web are highly variable in style, content and data formats. Combining…”
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Methylene blue in combination with sunlight as a low cost and effective disinfection method for coronavirus-contaminated PPE by Vos, Kevin A., Gordon, Paul M.K., Heyne, Belinda

“…Using the Murine Hepatitis Virus (MHV) A59 coronavirus as a SARS-CoV-2 animal surrogate, we validated that methylene blue (MB) in combination with sunlight…”
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An expression-directed linear mixed model discovering low-effect genetic variants by Li, Qing, Bian, Jiayi, Qian, Yanzhao, Kossinna, Pathum, Gau, Cooper, Gordon, Paul M K, Zhou, Xiang, Guo, Xingyi, Yan, Jun, Wu, Jingjing, Long, Quan

“…Detecting genetic variants with low-effect sizes using a moderate sample size is difficult, hindering downstream efforts to learn pathology and estimating…”
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