Search Results - "Gordon, Paul M"
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Transgenic mice overexpressing desmocollin-2 (DSC2) develop cardiomyopathy associated with myocardial inflammation and fibrotic remodeling
Published in PloS one (24-03-2017)“…Arrhythmogenic cardiomyopathy is an inherited heart muscle disorder leading to ventricular arrhythmias and heart failure, mainly as a result of mutations in…”
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Low Muscle Strength Thresholds for the Detection of Cardiometabolic Risk in Adolescents
Published in American journal of preventive medicine (01-05-2016)“…Introduction There is an association between strength and health among adolescents, yet, what remains to be determined is sex-specific cut points for low…”
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Resistance Exercise for the Aging Adult: Clinical Implications and Prescription Guidelines
Published in The American journal of medicine (01-03-2011)“…Abstract Sarcopenia and weakness are known to precipitate risk for disability, comorbidity, and diminished independence among aging adults. Resistance exercise…”
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Reconstructing SARS-CoV-2 infection dynamics through the phylogenetic inference of unsampled sources of infection
Published in PloS one (15-12-2021)“…The COVID-19 pandemic has illustrated the importance of infection tracking. The role of asymptomatic, undiagnosed individuals in driving infections within this…”
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5
A shared core microbiome in soda lakes separated by large distances
Published in Nature communications (17-09-2019)“…In alkaline soda lakes, concentrated dissolved carbonates establish productive phototrophic microbial mats. Here we show how microbial phototrophs and…”
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Strength capacity and cardiometabolic risk clustering in adolescents
Published in Pediatrics (Evanston) (01-04-2014)“…The purpose of this study was to determine the gender-specific independent association between muscular strength and cardiometabolic risk clustering in a large…”
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Characterization of microglial transcriptomes in the brain and spinal cord of mice in early and late experimental autoimmune encephalomyelitis using a RiboTag strategy
Published in Scientific reports (12-07-2021)“…Microglia play an important role in the pathogenesis of multiple sclerosis and the mouse model of MS, experimental autoimmune encephalomyelitis (EAE). To more…”
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Evaluating the effectiveness of ensemble voting in improving the accuracy of consensus signals produced by various DTWA algorithms from step-current signals generated during nanopore sequencing
Published in PLoS computational biology (01-09-2021)“…Nanopore sequencing device analysis systems simultaneously generate multiple picoamperage current signals representing the passage of DNA or RNA nucleotides…”
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Glucocorticoid-driven transcriptomes in human airway epithelial cells: commonalities, differences and functional insight from cell lines and primary cells
Published in BMC medical genomics (31-01-2019)“…Glucocorticoids act on the glucocorticoid receptor (GR; NR3C1) to resolve inflammation and, as inhaled corticosteroids (ICS), are the cornerstone of treatment…”
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10
Titin Mutation in Familial Restrictive Cardiomyopathy
Published in International journal of cardiology (15-01-2014)“…Abstract Background Familial restrictive cardiomyopathy (RCM) caused by a single gene mutation is the least common of the inherited cardiomyopathies. Only a…”
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Response of the Hyperthermophilic Archaeon Sulfolobus solfataricus to UV Damage
Published in Journal of Bacteriology (01-12-2007)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Sleep Duration Predicts Cardiometabolic Risk in Obese Adolescents
Published in The Journal of pediatrics (01-05-2014)“…Objective To examine the independent contributions of objectively measured sleep duration and fragmentation on cardiometabolic risk accumulation in free-living…”
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Skeletal muscle gene expression in response to resistance exercise: sex specific regulation
Published in BMC genomics (24-11-2010)“…The molecular mechanisms underlying the sex differences in human muscle morphology and function remain to be elucidated. The sex differences in the skeletal…”
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14
Resistance exercise training influences skeletal muscle immune activation: a microarray analysis
Published in Journal of applied physiology (1985) (01-02-2012)“…The primary aim of this investigation was to evaluate the effect of training on the immune activation in skeletal muscle in response to an acute bout of…”
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Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD): exome sequencing of trios, monozygotic twins and tumours
Published in Orphanet journal of rare diseases (25-08-2015)“…Rapid-onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD) is thought to be a genetic disease caused by de novo…”
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SnowyOwl: accurate prediction of fungal genes by using RNA-Seq and homology information to select among ab initio models
Published in BMC bioinformatics (01-07-2014)“…Locating the protein-coding genes in novel genomes is essential to understanding and exploiting the genomic information but it is still difficult to accurately…”
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Gene transcript and metabolite profiling of elicitor-induced opium poppy cell cultures reveals the coordinate regulation of primary and secondary metabolism
Published in Planta (01-04-2007)“…Elicitor-induced sanguinarine accumulation in opium poppy (Papaver somniferum) cell cultures provides a responsive model system to profile modulations in gene…”
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Alterations in Osteopontin Modify Muscle Size in Females in Both Humans and Mice
Published in Medicine and science in sports and exercise (01-06-2013)“…PURPOSEAn osteopontin (OPN; SPP1) gene promoter polymorphism modifies disease severity in Duchenne muscular dystrophy, and we hypothesized that it might also…”
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Influence of Resistance Exercise on Lean Body Mass in Aging Adults: A Meta-Analysis
Published in Medicine and science in sports and exercise (01-02-2011)“…sarcopenia plays a principal role in the pathogenesis of frailty and functional impairment that occur with aging. There are few published accounts that examine…”
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Glucocorticoid Receptor (NR3C1) Variants Associate with the Muscle Strength and Size Response to Resistance Training
Published in PloS one (28-01-2016)“…Glucocorticoid receptor (NR3C1) polymorphisms associate with obesity, muscle strength, and cortisol sensitivity. We examined associations among four NR3C1…”
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