Search Results - "Gordon, P H"

The natural history of primary lateral sclerosis by GORDON, P. H, CHENG, B, KATZ, I. B, PINTO, M, HAYS, A. P, MITSUMOTO, H, ROWLAND, L. P

“…To define the syndrome of primary lateral sclerosis (PLS) and disorders that contain features of both ALS and PLS, to determine the time beyond which PLS is…”
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The ALSFRSr predicts survival time in an ALS clinic population by KAUFMANN, P, LEVY, G, THOMPSON, J. L. P, DELBENE, M. L, BATTISTA, V, GORDON, P. H, ROWLAND, L. P, LEVIN, B, MITSUMOTO, H

“…To determine whether the Amyotrophic Lateral Sclerosis Functional Rating Scale-revised (ALSFRSr), a predictor of survival time in ALS clinical trials, predicts…”
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Clinical features that distinguish PLS, upper motor neuron―dominant ALS, and typical ALS by GORDON, P. H, CHENG, B, KATZ, I. B, MITSUMOTO, H, ROWLAND, L. P

“…To determine how clinical features at the first evaluation and in follow-up can be used to suggest a diagnostic outcome for patients with only upper motor…”
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Prevalence of fatigue and depression in ALS patients and change over time by McElhiney, M C, Rabkin, J G, Gordon, P H, Goetz, R, Mitsumoto, H

“…Background:Amyotrophic lateral sclerosis (ALS) patients report both fatigue and depression. It is not clear how frequently each occurs, to what extent they…”
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Quantitative objective markers for upper and lower motor neuron dysfunction in ALS by MITSUMOTO, H, ULUG, A. M, MONTES, J, HAYES, S, DASHNAW, S, KAUFMANN, P, GORDON, P. H, HIRSCH, J, LEVIN, B, ROWLAND, L. P, SHUNGU, D. C, PULLMAN, S. L, GOOCH, C. L, CHAN, S, TANG, M.-X, MAO, X, HAYS, A. P, FLOYD, A. G, BATTISTA, V

“…To investigate the value of objective biomarkers for upper (UMN) and lower (LMN) motor neuron involvement in ALS. We prospectively studied 64 patients with ALS…”
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Long-term outcome of rubber band ligation for symptomatic primary and recurrent internal hemorrhoids by IYER, V. S, SHRIER, I, GORDON, P. H

“…Rubber band ligation therapy for symptomatic hemorrhoidal disease has been used for many years and is a well-accepted treatment modality, but information on…”
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Natural history of patients with adhesive small bowel obstruction by Miller, G., Boman, J., Shrier, I., Gordon, P. H.

“…Background Small bowel obstruction (SBO) is a major cause of morbidity and financial expenditure. The goals of this study were to determine factors…”
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Development and evaluation of a self-administered version of the ALSFRS-R by MONTES, J, LEVY, G, ALBERT, S, KAUFMANN, P, BUCHSBAUM, R, GORDON, P. H, MITSUMOTO, H

“…We evaluated the reliability and sensitivity to change over time of a newly developed self-administered version of the ALS functional rating scale-revised…”
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Metabolomics in amyotrophic lateral sclerosis: how far can it take us? by Blasco, H., Patin, F., Madji Hounoum, B., Gordon, P. H., Vourc'h, P., Andres, C. R., Corcia, P.

“…Amyotrophic lateral sclerosis (ALS) is the most common adult‐onset motor neuron disease. Alongside identification of aetiologies, development of biomarkers is…”
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Placebo-controlled phase I/II studies of minocycline in amyotrophic lateral sclerosis by GORDON, P. H, MOORE, D. H, GELINAS, D. F, QUALLS, C, MEISTER, M. E, WERNER, J, MENDOZA, M, MASS, J, KUSHNER, G, MILLER, R. G

“…Two double-blind, randomized, placebo-controlled feasibility trials of minocycline in ALS were conducted. In Trial 1, 19 subjects received 200 mg/day or…”
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Amyotrophic Lateral Sclerosis, 2016: existing therapies and the ongoing search for neuroprotection by Blasco, H, Patin, F, Andres, C R, Corcia, P, Gordon, P H

“…Amyotrophic lateral sclerosis (ALS), one in a family of age-related neurodegenerative disorders, is marked by predominantly cryptogenic causes, partially…”
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Injuries sustained by colorectal surgeons performing colonoscopy by LIBEI-MAN, A. S, SHRIER, I, GORDON, P. H

“…Repetitive tasks in the workplace are one cause of injury. This study aimed to identify injuries specific to physicians routinely performing colonoscopy, and…”
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Biomarkers in amyotrophic lateral sclerosis: combining metabolomic and clinical parameters to define disease progression by Blasco, H., Nadal-Desbarats, L., Pradat, P.-F., Gordon, P. H., Madji Hounoum, B., Patin, F., Veyrat-Durebex, C., Mavel, S., Beltran, S., Emond, P., Andres, C. R., Corcia, P.

“…Background and purpose The objectives of this study were to define the metabolomic profile of cerebrospinal fluid in amyotrophic lateral sclerosis (ALS)…”
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Randomized controlled phase II trial of glatiramer acetate in ALS by GORDON, P. H, DOORISH, C, GENDELMAN, H. E, PRZEDBORSKI, S, MITSUMOTO, H, MONTES, J, MOSELY, R. L, DIAMOND, B, MACARTHUR, R. B, WEIMER, L. H, KAUFMANN, P, HAYS, A. P, ROWLAND, L. P

“…The authors conducted a randomized controlled trial to test the safety and immunology of glatiramer acetate in ALS. Twenty treated patients were randomly…”
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Respiratory onset in an ALS family with L144F SOD1 mutation by Corcia, P, Petiot, P, Stevic, Z, Vourc'h, P, Morales, R, Gordon, P H, Pageot, N, Andres, C, Camu, W

“…Familial amyotrophic lateral sclerosis (FALS) cases linked to SOD1 mutations may sometimes present with unusual clinical features such as pure lower motor…”
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Randomized trial of postoperative Adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum : National Surgical Adjuvant breast and Bowel Project Protocol R-02 by WOLMARK, N, WIEAND, H. S, PETRELLI, N. J, DEUTSCH, M, MAMOUNAS, E, WICKERHAM, D. L, FISHER, E. R, ROCKETTE, H, FISHER, B, HYAMS, D. M, COLANGELONI KOLAY, L, DIMITROV, V, ROMOND, E. H, WEXLER, M, PRAGER, D, CRUZ, A. B, GORDON, P. H

“…The conviction that postoperative radiotherapy and chemotherapy represent an acceptable standard of care for patients with Dukes' B (stage II) and Dukes' C…”
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Advances in Cellular Models to Explore the Pathophysiology of Amyotrophic Lateral Sclerosis by Veyrat-Durebex, C., Corcia, P., Dangoumau, A., Laumonnier, F., Piver, E., Gordon, P. H., Andres, C. R., Vourc’h, P., Blasco, H.

“…Amyotrophic lateral sclerosis (ALS), the most common adult-onset motor neuron disorder, is fatal for most patients less than 3 years from when the first…”
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The glutamate hypothesis in ALS: pathophysiology and drug development by Blasco, H, Mavel, S, Corcia, P, Gordon, P H

“…Amyotrophic lateral sclerosis (ALS) is an age-related neurodegenerative disorder that is believed to have complex genetic and environmental influences in the…”
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Disruption of an exon splicing enhancer in exon 3 of MLH1 is the cause of HNPCC in a Quebec family by McVety, S, Li, L, Gordon, P H, Chong, G, Foulkes, W D

“…Background: A 3 bp deletion located at the 5′ end of exon 3 of MLH1, resulting in deletion of exon 3 from RNA, was recently identified. Hypothesis: That this…”
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Dental erosion - changing prevalence? A review of British national childrens' surveys by Nunn, J. H., Gordon, P. H., Morris, A. J., Walker, A.

“…Objectives. To investigate the change in the prevalence of dental erosion, over time, by a review of the data from the published national dental surveys of…”
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