Temporomandibular Joint Involvement in Juvenile Idiopathic Arthritis: The Results from a Retrospective Cohort Tertial Center Study

Temporomandibular Joint Involvement in Juvenile Idiopathic Arthritis: The Results from a Retrospective Cohort Tertial Center Study

Our study aimed to evaluate the clinical and laboratory features of juvenile idiopathic arthritis (JIA) children with temporomandibular joint (TMJ) arthritis. In the retrospective cohort study, we analyzed data of 753 patients with JIA aged 2-17 years, depending on TMJ arthritis or not. TMJ arthriti...

Full description

Saved in:
Bibliographic Details
Published in:Life (Basel, Switzerland) Vol. 13; no. 5; p. 1164
Main Authors: Artamonov, Artem K, Kaneva, Maria A, Gordeeva, Natalia A, Sorokina, Lubov S, Kostik, Mikhail M
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 11-05-2023
MDPI
Subjects:
Arthritis
Biological products
Biological treatment
Brief Report
Complications and side effects
Confidence intervals
Corticoids
Corticosteroids
Diagnosis
Disease
Health services
Hip
Jaw
Joint diseases
Joints (anatomy)
Juvenile arthritis
juvenile idiopathic arthritis
Laboratories
Magnetic resonance imaging
Medical prognosis
Osteoarthritis
Pain
Patients
Pediatric research
Remission
Remission (Medicine)
Rheumatology
Risk factors
Spine
Spine (cervical)
Statistical analysis
Steroids
Survival analysis
Temporomandibular joint
Temporomandibular joint disorders
TMJ
TMJ arthritis
Variables
Russia
TMJ
corticosteroids
juvenile idiopathic arthritis
temporomandibular joint
TMJ arthritis
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Our study aimed to evaluate the clinical and laboratory features of juvenile idiopathic arthritis (JIA) children with temporomandibular joint (TMJ) arthritis. In the retrospective cohort study, we analyzed data of 753 patients with JIA aged 2-17 years, depending on TMJ arthritis or not. TMJ arthritis can to be diagnosed in the presence of at least two of the following clinical signs of inflammation: pain in TMJ, jaw opening limitation, jaw opening deviation, and micrognathia. We compared clinical, laboratory, and treatment features in JIA patients depending on the involvement of TMJ. TMJ arthritis was detected in 43 (5.7%) of our patients and associated with a longer course of the disease, polyarticular JIA category, treatment with systemic corticosteroids, and longer achievement of the remission and involvement of cervical spine, hip, and shoulder. Active joints >8 (OR = 14.9, = 0.0000001), delayed remission >7 years (OR = 3.1; = 0.0004), delayed hip involvement (OR = 4.6; = 0.041), hip osteoarthritis (OR = 4.0; = 0.014), cervical spine arthritis (OR = 10.3, = 0.000001), and corticosteroid treatment (OR = 2.3, = 0.0007) were associated with TMJ involvement. Patients with TMJ arthritis require more biologics (OR = 3.2, = 0.0006, HR = 2.4, = 0.005) and have decreased probability of remission achievement ( = 0.014). Consequently, TMJ arthritis was associated with a severe disease course. Early biologic treatment and corticosteroid avoidance might decrease TMJ involvement.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:2075-1729
2075-1729
DOI:10.3390/life13051164