Search Results - "Gordeeva, E. A."
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Protective Effect of Peroxiredoxin 6 in Ischemia/Reperfusion-Induced Damage of Small Intestine
Published in Digestive diseases and sciences (01-12-2015)“…Background Strong oxidative stress starting in the epithelium upon restoration of blood cell circulation is a major cause of necrosis of the intestinal…”
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Solid-phase assays for study of carbohydrate specificity of galectins
Published in Biochemistry (Moscow) (01-03-2010)“…We have recently shown that the carbohydrate-binding pattern of galectins in cells differs from that determined in artificial (non-cellular) test-systems. To…”
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3
The effect of exogenous peroxiredoxin 6 on morphofunctional state of isolated rat kidney
Published in Vestnik transplantologii i iskusstvennykh organov (16-09-2021)“…Objective: to investigate the role of peroxiredoxin 6 (PRX6) in preserving the morphofunctional state of ischemic isolated kidney during perfusion.Materials…”
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Synthesis of new derivatives of 5-alkyl-6-(2,6-dihalobenzyl)-2-(methylsulfanyl)pyrimidin-4(3H)-one and the features of their oxidation
Published in Russian journal of organic chemistry (01-11-2010)“…The synthesis and features of the regioselective S-monomethylation of new 5-alkyl-6-(arylmethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-ones were investigated,…”
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Nutritional problems of patients infected with COVID-19 and potential for nutritional management of disorders
Published in Medicinskij sovet (20-04-2021)“…Introduction . One of the most significant issues that require close attention in the treatment and rehabilitation of patients with coronovirus infection is…”
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Enzymatic antioxidant system of endotheliocytes
Published in Doklady. Biochemistry and biophysics (01-11-2016)“…It is shown that endothelial cells from human umbilical vein have a reduced activity and gene expression of the “classic” antioxidant enzymes (Cu,Zn-superoxide…”
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Interaction of myelin basic protein and 2′,3′-cyclic nucleotide phosphodiesterase with mitochondria
Published in Biochemistry (Moscow) (01-06-2014)“…The content and distribution of myelin basic protein (MBP) isoforms (17 and 21.5 kDa) as well as 2′,3′-cyclic nucleotide-3′-phosphodiesterase (CNPase) were…”
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Improving infant formulas: on the way to approaching breast milk
Published in Medicinskij sovet (30-12-2016)“…Breast milk is the gold standard of infant feeding during the first year of life that ensures adequate physical and psychological development. The composition…”
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Immunogenic and Protective Properties of Neisseria meningitidis IgA1 Protease and of Its Truncated Fragments
Published in Russian journal of bioorganic chemistry (2018)“…Four recombinant proteins, MA 28 –P 1004 LEH 6 , ME 135 –H 328 LEH 6 , MW 329 –H 622 LEH 6 and MH 835 –P 1004 LEH 6 , were prepared based on the genomic…”
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Peculiarities of the Formation of Antimeningococcus Immunity in Mice Immunized with Fragments of N. meningitidis IgA1 Protease
Published in Bulletin of experimental biology and medicine (01-10-2018)“…We studied immunogenicity of two recombinant proteins FR.9 and FR.11-3 created on the basis of fragments of the primary structure of N. meningitidis IgA1…”
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Peroxiredoxin 6 is a natural radioprotector
Published in Doklady. Biochemistry and biophysics (01-03-2016)“…After injection of 20 mg/kg peroxiredoxin 6 to male Kv:SHK mice 15 min before X-ray irradiation in the range of lethal doses (7–10 Gy), the mice remained alive…”
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Serological Analysis of Immunogenic Properties of Recombinant Meningococcus IgA1 Protease-Based Proteins
Published in Bulletin of experimental biology and medicine (01-07-2016)“…Using the genome sequence of IgA1 protease of N. meningitidis of serogroup B, four recombinant proteins of different structure and molecular weight were…”
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13
Use of Peroxiredoxin 6 to Prevent Liver Dysfunction in Acute Kidney Injury
Published in Biophysics (Oxford) (01-08-2023)“…Acute kidney injury provokes liver dysfunction, which is an aggravating factor for effective treatment. In this study, ischemic-reperfusion kidney injury was…”
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The Hepatoprotective Effect of Peroxiredoxin 6 in Ischemia–Reperfusion Kidney Injury
Published in Biophysics (Oxford) (01-09-2021)“…Oxidative stress caused by ischemia–reperfusion kidney injury may play a key role in liver dysfunction. To reduce liver and kidney damage in…”
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15
Peroxiredoxin 6 Prevents Reperfusion Injury to Isolated Rat Kidney
Published in Biophysics (Oxford) (2022)“…Ischemia-reperfusion (I-R) injury causes a reduction in the viability of donor organs during long-term conservation. In the present study, an antioxidant…”
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Protective properties of recombinant IgA1 protease from meningococcus
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-10-2013)“…The study of enzymatic and protective properties of recombinant IgA1 protease in active and mutant form has shown that the active form of IgA1 protease…”
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Reactions of 6-benzyl-5-methyl-2-(methylsulfanyl)pyrimidin-4(3H)-one with aliphatic and aliphatic-aromatic amines
Published in Russian journal of organic chemistry (01-05-2009)“…The rules were investigated of the regioselective synthesis of N 2 -substituted derivatives of 2-amino-6-benzyl-5-methylpyrimidin-4(3 H )-one from…”
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18
Efficient solid-phase synthesis of isocytosine derivatives
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (01-11-2009)“…We have investigated the potential use of a solid-phase synthesis of novel 6-(arylmethyl)-5-methyl-isocytosine derivatives based on the immobilization of the…”
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19
specific character of the reaction of derivatives of 2-thioxo-2,3-dihydropyrimidin-4(1H)-one with iodomethane and alkyl chloromethyl sulfides
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (01-06-2010)“…The alkylation of 5-alkyl-6-(2,6-dihalobenzyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-ones with MeI, AllSCH₂Cl, and MeSCH₂Cl in the K₂CO₃-DMF, NaOMe-MeOH, and…”
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Application of the Miles Assay to Study Microvascular Permeability in Ischemia–Reperfusion Injury of the Small Intestine
Published in Biophysics (Oxford) (01-05-2019)“…—The Miles assay using Evans Blue dye is a conventional method to assess vascular permeability. The penetration Evans dye into intestinal tissue was studied in…”
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