Search Results - "Gorczyca, Michele M"

Ofatumumab plus fludarabine and cyclophosphamide in relapsed chronic lymphocytic leukemia: results from the COMPLEMENT 2 trial by Robak, Tadeusz, Warzocha, Krzysztof, Govind Babu, K., Kulyaba, Yaroslav, Kuliczkowski, Kazimierz, Abdulkadyrov, Kudrat, Loscertales, Javier, Kryachok, Iryna, Kłoczko, Janusz, Rekhtman, Grygoriy, Homenda, Wojciech, Błoński, Jerzy Z., McKeown, Astrid, Gorczyca, Michele M., Carey, Jodi L., Chang, Chai-Ni, Lisby, Steen, Gupta, Ira V., Grosicki, Sebastian

“…In this multicenter, open-label, phase III study, patients with relapsed chronic lymphocytic leukemia (CLL) were randomized (1:1) to receive ofatumumab plus…”
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Targeting B-cell maturation antigen with GSK2857916 antibody–drug conjugate in relapsed or refractory multiple myeloma (BMA117159): a dose escalation and expansion phase 1 trial by Trudel, Suzanne, Lendvai, Nikoletta, Popat, Rakesh, Voorhees, Peter M, Reeves, Brandi, Libby, Edward N, Richardson, Paul G, Anderson, Larry D, Sutherland, Heather J, Yong, Kwee, Hoos, Axel, Gorczyca, Michele M, Lahiri, Soumi, He, Zangdong, Austin, Daren J, Opalinska, Joanna B, Cohen, Adam D

“…B-cell maturation antigen (BCMA) is a cell-surface receptor of the tumour necrosis superfamily required for plasma cell survival. BMCA is universally detected…”
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Inhibition of human cytomegalovirus protease by enedione derivatives of thieno[2,3-d]oxazinones through a novel dual acylation/alkylation mechanism by Pinto, Ivan L., Jarvest, Richard L., Clarke, Brian, Dabrowski, Christine E., Fenwick, Ashley, Gorczyca, Michele M, Jennings, L.John, Lavery, Patrick, Sternberg, Edmund J, Tew, David G., West, Andrew

“…Enedione derivatives of thieno[2,3-d]oxazinones are nanomolar inhibitors of CMV protease which act through a novel dual acylation of the catalytic serine and…”
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Correlations Between Ofatumumab Exposure and Treatment Outcomes for Patients with Chronic Lymphocytic Leukemia (CLL) Treated with Frontline Ofatumumab, Fludarabine, and Cyclophosphamide Chemoimmunotherapy by Wierda, William G., Jewell, Roxanne C., Kipps, Thomas J., Dürig, Jan, Griskevicius, Laimonas, Stilgenbauer, Stephan, Smolej, Lukas, Hess, Georg, Hernandez-Ilizaliturri, Francisco J., Padmanabhan, Swaminathan, Fang, Lei, Gorczyca, Michele M., Chan, Geoffrey W., Gupta, Ira V., Lisby, Steen

“…Abstract 1793 Results: Seven pts (4 male) with a medianLittle is known about the pharmacokinetics (PK) and pharmacodynamics of CD20 monoclonal antibody (mAb)…”
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Final Analysis From the International Trial of Single-Agent Ofatumumab In Patients with Fludarabine-Refractory Chronic Lymphocytic Leukemia by Wierda, William G., Kipps, Thomas J., Mayer, Jiri, Robak, Tadeusz, Dyer, Martin JS, Furman, Richard R., Hillmen, Peter, Stilgenbauer, Stephan, Williams, Catherine D., Trneny, Marek, Cartron, Guillaume, Hernandez-Ilizaliturri, Francisco J., Padmanabhan, Swaminathan, Chan, Geoffrey W., Gupta, Ira V., Gorczyca, Michele M., Davis, Randy L., Losic, Nedjad, Lisby, Steen, Österborg, Anders

“…Abstract 921 Patients with chronic lymphocytic leukemia (CLL) refractory to fludarabine and alemtuzumab (FA-ref) or refractory to fludarabine with bulky (>5…”
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