Search Results - "Gorczyca, Michael"
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Ranking of environmental heat stressors for dairy cows using machine learning algorithms
Published in Computers and electronics in agriculture (01-01-2020)“…•Machine learning is used to predict physiological responses of dairy cows.•Environmental heat stressors were the predictors.•Machine learning is used to rank…”
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On quantifying heterogeneous treatment effects with regression‐based individualized treatment rules: Loss function families and bounds on estimation error
Published in Stat (International Statistical Institute) (01-06-2024)“…Summary Heterogeneity in response to treatment is a pervasive problem in medicine. Many researchers have proposed individualized treatment rule methods for…”
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Preoperative measurement of the thickness of the center of the humeral head predicts screw cutout after locked plating of proximal humeral fractures
Published in Journal of shoulder and elbow surgery (01-01-2021)“…Preoperative computed tomography (CT) scans can be used to measure the thickness of the center of the humeral head to identify patients at a higher risk of…”
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A single pair of interneurons commands the Drosophila feeding motor program
Published in Nature (London) (04-07-2013)“…A pair of Drosophila brain cells is identified and its activation alone is found to induce the fly’s complete feeding motor routine when artificially induced;…”
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Machine learning algorithms to predict core, skin, and hair-coat temperatures of piglets
Published in Computers and electronics in agriculture (01-08-2018)“…•Prediction of temperatures of livestock using machine learning.•Environmental data were the predictors.•Random forest, gradient boosting machine, and deep…”
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Disentangling transcriptomic heterogeneity within the human subgenual anterior cingulate cortex
Published in Cerebral cortex (New York, N.Y. 1991) (03-07-2024)“…Abstract The subgenual anterior cingulate cortex (sgACC) is a critical site for understanding the neural correlates of affect and emotion. While the activity…”
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The trauma severity model: An ensemble machine learning approach to risk prediction
Published in Computers in biology and medicine (01-05-2019)“…Statistical theory indicates that a flexible model can attain a lower generalization error than an inflexible model, provided that the setting is appropriate…”
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Experimental design and power calculation in omics circadian rhythmicity detection using the cosinor model
Published in Statistics in medicine (15-08-2023)“…Summary Circadian clocks are 24‐h endogenous oscillators in physiological and behavioral processes. Though recent transcriptomic studies have been successful…”
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Rapid Activity-Dependent Modifications in Synaptic Structure and Function Require Bidirectional Wnt Signaling
Published in Neuron (Cambridge, Mass.) (13-03-2008)“…Activity-dependent modifications in synapse structure play a key role in synaptic development and plasticity, but the signaling mechanisms involved are poorly…”
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Rapid Eye Movement Sleep Engages Melanin-Concentrating Hormone Neurons to Reduce Cocaine Seeking
Published in Biological psychiatry (1969) (01-12-2022)“…Persistent sleep disruptions following withdrawal from abused drugs may hold keys to battle drug relapse. It is posited that there may be sleep signatures that…”
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Local neuropeptide signaling modulates serotonergic transmission to shape the temporal organization of C. elegans egg-laying behavior
Published in PLoS genetics (06-04-2017)“…Animal behaviors are often composed of distinct alternating behavioral states. Neuromodulatory signals are thought to be critical for establishing stable…”
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The Drosophila Wnt, Wingless, Provides an Essential Signal for Pre- and Postsynaptic Differentiation
Published in Cell (01-11-2002)“…At vertebrate neuromuscular junctions (NMJs), Agrin plays pivotal roles in synapse development, but molecules that activate synapse formation at central…”
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Selected methods for the anatomical study of Drosophila embryonic and larval neuromuscular junctions
Published in International review of neurobiology (01-01-2006)Get more information
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Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP
Published in Proceedings of the National Academy of Sciences - PNAS (16-05-2006)“…The Wingless pathway plays an essential role during synapse development. Recent studies at Drosophila glutamatergic synapses suggest that Wingless is secreted…”
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Rethinking strategies for blood transfusion in hip fracture patients
Published in OTA international : the open access journal of orthopaedic trauma (01-09-2020)“…Most patients can tolerate a hemoglobin (Hgb) > 8 g per deciliter. In some cases, however, transfusion will delay physical therapy and hospital discharge. This…”
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A large-scale behavioral screen to identify neurons controlling motor programs in the Drosophila brain
Published in G3 : genes - genomes - genetics (01-10-2013)“…Drosophila is increasingly used for understanding the neural basis of behavior through genetically targeted manipulation of specific neurons. The primary…”
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Regulation of Synapse Structure and Function by the Drosophila Tumor Suppressor Gene dlg
Published in Neuron (Cambridge, Mass.) (01-10-1996)“…Mutations of the tumor suppressor gene discs-large (dlg) lead to postsynaptic structural defects. Here, we report that mutations in dlg also result in larger…”
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Octopamine immunoreactivity in the fruit fly Drosophila melanogaster
Published in Journal of comparative neurology (1911) (29-05-1995)“…Octopamine has been proposed as a neurotransmitter/modulator/hormone serving a variety of physiological functions in invertebrates. We have initiated a study…”
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353. The Role of Specific Bipolar Disorder-Associated Risk Genes in Rhythmic Gene Expression
Published in Biological psychiatry (1969) (01-05-2023)Get full text
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