Search Results - "Gorbalenya, Alexander"

One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities by Subissi, Lorenzo, Posthuma, Clara C, Collet, Axelle, Zevenhoven-Dobbe, Jessika C, Gorbalenya, Alexander E, Decroly, Etienne, Snijder, Eric J, Canard, Bruno, Imbert, Isabelle

“…Significance The 2003 severe acute respiratory syndrome (SARS) epidemic and recent emergence of Middle East respiratory syndrome highlight the potential…”
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Changes to taxonomy and the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2017) by Adams, Michael J., Lefkowitz, Elliot J., King, Andrew M. Q., Harrach, Balázs, Harrison, Robert L., Knowles, Nick J., Kropinski, Andrew M., Krupovic, Mart, Kuhn, Jens H., Mushegian, Arcady R., Nibert, Max, Sabanadzovic, Sead, Sanfaçon, Hélène, Siddell, Stuart G., Simmonds, Peter, Varsani, Arvind, Zerbini, Francisco Murilo, Gorbalenya, Alexander E., Davison, Andrew J.

“…This article lists the changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses (ICTV) in March 2017…”
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What's what in a pandemic? Virus, disease, and societal disaster must be differentiated by Gorbalenya, Alexander E, Perlman, Stanley

“…Viruses, the diseases they can trigger, and the possible associated societal disaster represent different entities. To engage with the complexities of viral…”
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PLOS Pathogens expanding horizons by Squarr, Julia, Kirk, Rebecca, Gorbalenya, Alexander E, Malim, Michael

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A nidovirus perspective on SARS-CoV-2 by Gulyaeva, Anastasia A., Gorbalenya, Alexander E.

“…Two pandemics of respiratory distress diseases associated with zoonotic introductions of the species Severe acute respiratory syndrome-related coronavirus in…”
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Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2016) by Adams, Michael J., Lefkowitz, Elliot J., King, Andrew M. Q., Harrach, Balázs, Harrison, Robert L., Knowles, Nick J., Kropinski, Andrew M., Krupovic, Mart, Kuhn, Jens H., Mushegian, Arcady R., Nibert, Max, Sabanadzovic, Sead, Sanfaçon, Hélène, Siddell, Stuart G., Simmonds, Peter, Varsani, Arvind, Zerbini, Francisco Murilo, Gorbalenya, Alexander E., Davison, Andrew J.

“…This article lists the changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses (ICTV) in April 2016. Changes to…”
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Coronavirus replication–transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit by Slanina, Heiko, Madhugiri, Ramakanth, Bylapudi, Ganesh, Schultheiß, Karin, Karl, Nadja, Gulyaeva, Anastasia, Gorbalenya, Alexander E., Linne, Uwe, Ziebuhr, John

“…RNA-dependent RNA polymerases (RdRps) of the Nidovirales (Coronaviridae, Arteriviridae, and 12 other families) are linked to an amino-terminal (N-terminal)…”
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Recognizing species as a new focus of virus research by Gorbalenya, Alexander E, Siddell, Stuart G

“…Species taxa are the units of taxonomy most suited to measure virus diversity, and they account for more than 70% of all virus taxa. Yet, as evidenced by the…”
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Increasing the number of available ranks in virus taxonomy from five to ten and adopting the Baltimore classes as taxa at the basal rank by Gorbalenya, Alexander E.

“…This opinion article makes a case for increasing the number of ranks used in virus taxonomy from the current five to ten (as are used to classify cellular life…”
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Antagonism of the Interferon-Induced OAS-RNase L Pathway by Murine Coronavirus ns2 Protein Is Required for Virus Replication and Liver Pathology by Zhao, Ling, Jha, Babal K., Wu, Ashley, Elliott, Ruth, Ziebuhr, John, Gorbalenya, Alexander E., Silverman, Robert H., Weiss, Susan R.

“…Many viruses induce hepatitis in humans, highlighting the need to understand the underlying mechanisms of virus-induced liver pathology. The murine…”
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Modulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C Virus by Dorobantu, Cristina M, Albulescu, Lucian, Harak, Christian, Feng, Qian, van Kampen, Mirjam, Strating, Jeroen R P M, Gorbalenya, Alexander E, Lohmann, Volker, van der Schaar, Hilde M, van Kuppeveld, Frank J M

“…Cardioviruses, including encephalomyocarditis virus (EMCV) and the human Saffold virus, are small non-enveloped viruses belonging to the Picornaviridae, a…”
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Deep mining of the Sequence Read Archive reveals major genetic innovations in coronaviruses and other nidoviruses of aquatic vertebrates by Lauber, Chris, Zhang, Xiaoyu, Vaas, Josef, Klingler, Franziska, Mutz, Pascal, Dubin, Arseny, Pietschmann, Thomas, Roth, Olivia, Neuman, Benjamin W, Gorbalenya, Alexander E, Bartenschlager, Ralf, Seitz, Stefan

“…Virus discovery by genomics and metagenomics empowered studies of viromes, facilitated characterization of pathogen epidemiology, and redefined our…”
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Changes to taxonomy and the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2018) by King, Andrew M. Q., Lefkowitz, Elliot J., Mushegian, Arcady R., Adams, Michael J., Dutilh, Bas E., Gorbalenya, Alexander E., Harrach, Balázs, Harrison, Robert L., Junglen, Sandra, Knowles, Nick J., Kropinski, Andrew M., Krupovic, Mart, Kuhn, Jens H., Nibert, Max L., Rubino, Luisa, Sabanadzovic, Sead, Sanfaçon, Hélène, Siddell, Stuart G., Simmonds, Peter, Varsani, Arvind, Zerbini, Francisco Murilo, Davison, Andrew J.

“…This article lists the changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses in February 2018. A total of 451…”
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Discovery of a new human polyomavirus associated with trichodysplasia spinulosa in an immunocompromized patient by van der Meijden, Els, Janssens, René W A, Lauber, Chris, Bouwes Bavinck, Jan Nico, Gorbalenya, Alexander E, Feltkamp, Mariet C W

“…The Polyomaviridae constitute a family of small DNA viruses infecting a variety of hosts. In humans, polyomaviruses can cause infections of the central nervous…”
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Discovery of the first insect nidovirus, a missing evolutionary link in the emergence of the largest RNA virus genomes by Nga, Phan Thi, Parquet, Maria del Carmen, Lauber, Chris, Parida, Manmohan, Nabeshima, Takeshi, Yu, Fuxun, Thuy, Nguyen Thanh, Inoue, Shingo, Ito, Takashi, Okamoto, Kenta, Ichinose, Akitoyo, Snijder, Eric J, Morita, Kouichi, Gorbalenya, Alexander E

“…Nidoviruses with large genomes (26.3-31.7 kb; 'large nidoviruses'), including Coronaviridae and Roniviridae, are the most complex positive-sense…”
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Bioinformatics of virus taxonomy: foundations and tools for developing sequence-based hierarchical classification by Gorbalenya, Alexander E, Lauber, Chris

“…•The genome sequence is the only characteristic readily obtainable for all viruses.•Comparative genomics enables building hierarchical classification for virus…”
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The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 by Gorbalenya, Alexander E, Baker, Susan C, Baric, Ralph S, de Groot Raoul J, Drosten, Christian, Gulyaeva, Anastasia A, Haagmans, Bart L, Lauber, Chris, Leontovich, Andrey M, Neuman, Benjamin W, Penzar Dmitry, Perlman, Stanley, Poon Leo L M, Samborskiy, Dmitry V, Sidorov, Igor A, Sola, Isabel, Ziebuhr, John

“…The present outbreak of a coronavirus-associated acute respiratory disease called coronavirus disease 19 (COVID-19) is the third documented spillover of an…”
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ICTV Virus Taxonomy Profile: Arteriviridae 2021 by Brinton, Margo A., Gulyaeva, Anastasia A., Balasuriya, Udeni B. R., Dunowska, Magda, Faaberg, Kay S., Goldberg, Tony, Leung, Frederick C. C., Nauwynck, Hans J., Snijder, Eric J., Stadejek, Tomasz, Gorbalenya, Alexander E.

“…The family Arteriviridae comprises enveloped RNA viruses with a linear, positive-sense genome of approximately 12.7 to 15.7 kb. The spherical, pleomorphic…”
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50 years of the International Committee on Taxonomy of Viruses: progress and prospects by Adams, Michael J., Lefkowitz, Elliot J., King, Andrew M. Q., Harrach, Balázs, Harrison, Robert L., Knowles, Nick J., Kropinski, Andrew M., Krupovic, Mart, Kuhn, Jens H., Mushegian, Arcady R., Nibert, Max L., Sabanadzovic, Sead, Sanfaçon, Hélène, Siddell, Stuart G., Simmonds, Peter, Varsani, Arvind, Zerbini, Francisco Murilo, Orton, Richard J., Smith, Donald B., Gorbalenya, Alexander E., Davison, Andrew J.

“…We mark the 50th anniversary of the International Committee on Taxonomy of Viruses (ICTV) by presenting a brief history of the organization since its…”
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Partitioning the Genetic Diversity of a Virus Family: Approach and Evaluation through a Case Study of Picornaviruses by Lauber, Chris, Gorbalenya, Alexander E

“…The recent advent of genome sequences as the only source available to classify many newly discovered viruses challenges the development of virus taxonomy by…”
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