Search Results - "Gopalan, Venkat"
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Archaeal/Eukaryal RNase P: subunits, functions and RNA diversification
Published in Nucleic acids research (01-12-2010)“…RNase P, a catalytic ribonucleoprotein (RNP), is best known for its role in precursor tRNA processing. Recent discoveries have revealed that eukaryal RNase P…”
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The amazing potential of fungi: 50 ways we can exploit fungi industrially
Published in Fungal diversity (01-07-2019)“…Fungi are an understudied, biotechnologically valuable group of organisms. Due to the immense range of habitats that fungi inhabit, and the consequent need to…”
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Uniformity amid diversity in RNase P
Published in Proceedings of the National Academy of Sciences - PNAS (13-02-2007)Get full text
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A Land Plant-Specific Transcription Factor Directly Enhances Transcription of a Pathogenic Noncoding RNA Template by DNA-Dependent RNA Polymerase II
Published in The Plant cell (01-05-2016)“…Some DNA-dependent RNA polymerases (DdRPs) possess RNA-dependent RNA polymerase activity, as was first discovered in the replication of Potato spindle tuber…”
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Use of Proteomic Analysis To Elucidate the Role of Calcium in Acetone-Butanol-Ethanol Fermentation by Clostridium beijerinckii NCIMB 8052
Published in Applied and Environmental Microbiology (01-01-2013)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Unexpected diversity of RNase P, an ancient tRNA processing enzyme: Challenges and prospects
Published in FEBS letters (21-01-2010)“…For an enzyme functioning predominantly in a seemingly housekeeping role of 5′ tRNA maturation, RNase P displays a remarkable diversity in subunit make-up…”
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Both kinds of RNase P in all domains of life: surprises galore
Published in RNA (Cambridge) (01-03-2019)“…RNase P, an essential housekeeping endonuclease needed for 5'-processing of tRNAs, exists in two distinct forms: one with an RNA- and the other with a…”
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Overexpression of stress granule protein TZF1 enhances salt stress tolerance by targeting ACA11 mRNA for degradation in Arabidopsis
Published in Frontiers in plant science (2024)“…Tandem CCCH zinc finger (TZF) proteins play diverse roles in plant growth and stress response. Although as many as 11 TZF proteins have been identified in ,…”
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Acetone production in solventogenic Clostridium species: new insights from non-enzymatic decarboxylation of acetoacetate
Published in Applied microbiology and biotechnology (01-08-2011)“…Development of a butanologenic strain with high selectivity for butanol production is often proposed as a possible route for improving the economics of…”
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Ribosomal protein L7Ae is a subunit of archaeal RNase P
Published in Proceedings of the National Academy of Sciences - PNAS (17-08-2010)“…To the mounting evidence of nonribosomal functions for ribosomal proteins, we now add L7Ae as a subunit of archaeal RNase P, a ribonucleoprotein (RNP) that…”
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The L7Ae protein binds to two kink-turns in the Pyrococcus furiosus RNase P RNA
Published in Nucleic acids research (01-12-2014)“…The RNA-binding protein L7Ae, known for its role in translation (as part of ribosomes) and RNA modification (as part of sn/oRNPs), has also been identified as…”
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Dissecting functional cooperation among protein subunits in archaeal RNase P, a catalytic ribonucleoprotein complex
Published in Nucleic acids research (01-12-2010)“…RNase P catalyzes the Mg²⁺-dependent 5'-maturation of precursor tRNAs. Biochemical studies on the bacterial holoenzyme, composed of one catalytic RNase P RNA…”
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13
Cleavage of Model Substrates by Arabidopsis thaliana PRORP1 Reveals New Insights into Its Substrate Requirements
Published in PloS one (05-08-2016)“…Two broad classes of RNase P trim the 5' leader of precursor tRNAs (pre-tRNAs): ribonucleoprotein (RNP)- and proteinaceous (PRORP)-variants. These two RNase P…”
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Ribozyme-Mediated Downregulation Uncovers DNA Integrity Scanning Protein A (DisA) as a Solventogenesis Determinant in Clostridium beijerinckii
Published in Frontiers in bioengineering and biotechnology (08-06-2021)“…Carbon catabolite repression (CCR) limits microbial utilization of lignocellulose-derived pentoses. To relieve CCR in Clostridium beijerinckii NCIMB 8052, we…”
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Functional Reconstitution and Characterization of Pyrococcus furiosus RNase P
Published in Proceedings of the National Academy of Sciences - PNAS (31-10-2006)“…RNase P, which catalyzes the magnesium-dependent 5'-end maturation of tRNAs in all three domains of life, is composed of one essential RNA and a varying number…”
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Discovery of a minimal form of RNase P in Pyrobaculum
Published in Proceedings of the National Academy of Sciences - PNAS (28-12-2010)“…RNase P RNA is an ancient, nearly universal feature of life. As part of the ribonucleoprotein RNase P complex, the RNA component catalyzes essential removal of…”
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Transcriptional control of an essential ribozyme in Drosophila reveals an ancient evolutionary divide in animals
Published in PLoS genetics (01-01-2015)“…Ribonuclease P (RNase P) is an essential enzyme required for 5'-maturation of tRNA. While an RNA-free, protein-based form of RNase P exists in eukaryotes, the…”
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Thermodynamics of Coupled Folding in the Interaction of Archaeal RNase P Proteins RPP21 and RPP29
Published in Biochemistry (Easton) (31-01-2012)“…We have used isothermal titration calorimetry (ITC) to identify and describe binding-coupled equilibria in the interaction between two protein subunits of…”
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Serendipitous Discovery of a Competitive Inhibitor of FraB, a Salmonella Deglycase and Drug Target
Published in Pathogens (Basel) (26-09-2022)“…Although salmonellosis, an infectious disease, is a significant global healthcare burden, there are no -specific vaccines or therapeutics for humans. Motivated…”
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Solution Structure of an Archaeal RNase P Binary Protein Complex: Formation of the 30-kDa Complex between Pyrococcus furiosus RPP21 and RPP29 Is Accompanied by Coupled Protein Folding and Highlights Critical Features for Protein–Protein and Protein–RNA Interactions
Published in Journal of molecular biology (13-11-2009)“…Ribonuclease P (RNase P) is a ribonucleoprotein (RNP) enzyme that catalyzes the Mg 2+-dependent 5′ maturation of precursor tRNAs. In all domains of life, it is…”
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