Search Results - "Gopalakrishnan, Singaram"
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A Unidirectional Cell Switching Gate by Engineering Grating Length and Bending Angle
Published in PloS one (28-01-2016)“…On a microgrooved substrate, cells migrate along the pattern, and at random positions, reverse their directions. Here, we demonstrate that these reversals can…”
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Modulation of immune-associated parameters and antioxidant responses in the crab (Scylla serrata) exposed to mercury
Published in Chemosphere (Oxford) (01-01-2013)“…► A 14d exposure of Hg induces physiological changes in the immune system of crab. ► The approach is based on utilizing the commercial crab Scylla serrata. ►…”
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A Rapid Bioassay Test for Assessing Environmental Contamination Using the Marine Sedentary Polychaete Hydroides elegans
Published in Water (Basel) (01-06-2022)“…To investigate the impact of environmental contaminants on the early life stages of the marine polychaetae Hydroides elegans, a toxicity test was designed. In…”
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Modulation of biotransformation enzymes leads to oxidative stress and DNA damage in naphthalene exposed marine bivalve Perna viridis
Published in Frontiers in Marine Science (04-08-2022)Get full text
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Microplastics in Demersal Sharks From the Southeast Indian Coastal Region
Published in Frontiers in Marine Science (26-05-2022)“…Microplastic (MPs) contamination has emerged as a serious worldwide issue. Human activity, commercial enterprises, and fishing are concentrated around the…”
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Japanese medaka: a non-mammalian vertebrate model for studying sex and age-related bone metabolism in vivo
Published in PloS one (11-02-2014)“…In human, a reduction in estrogen has been proposed as one of the key contributing factors for postmenopausal osteoporosis. Rodents are conventional models for…”
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Microplastic contamination in commercial fish species in southern coastal region of India
Published in Chemosphere (Oxford) (01-02-2023)“…Due to its potential impact on food safety and human health, commercial species that have been contaminated with microplastics (MPs) are drawing more attention…”
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Effect of microfibers induced toxicity in marine sedentary polychaete Hydroides elegans: Insight from embryogenesis axis
Published in The Science of the total environment (01-01-2024)“…Presence of surgical face masks in the environment are more than ever before after the COVID-19 pandemic, and it poses a newer threat to aquatic habitats…”
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Weathered polyethylene microplastics induced immunomodulation in zebrafish
Published in Environmental toxicology and pharmacology (01-08-2024)“…Microplastics are pollutants of emerging concern and the aquatic biota consumes microplastics (MPs), which has a range of toxicological and environmental…”
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Effect of 17β-estradiol on the immunocompetence of Japanese sea bass (Lateolabrax japonicus)
Published in Environmental toxicology and chemistry (01-08-2009)“…Environmental contaminants can interfere with hormonal regulation in both vertebrates and invertebrates, and these contaminants may disrupt the endocrine…”
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Proteomic characterization of the interactions between fish serum proteins and waterborne bacteria reveals the suppression of anti-oxidative defense as a serum-mediated antimicrobial mechanism
Published in Fish & shellfish immunology (01-03-2017)“…Fish blood is one of the crucial tissues of innate immune system, but the full repertoire of fish serum components involved in antibacterial defense is not…”
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A Rapid Bioassay Test for Assessing Environmental Contamination Using the Marine Sedentary Polychaete IHydroides elegans/I
Published in Water (Basel) (01-06-2022)“…To investigate the impact of environmental contaminants on the early life stages of the marine polychaetae Hydroides elegans, a toxicity test was designed. In…”
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Comparative study of 17 β-estradiol on endocrine disruption and biotransformation in fingerlings and juveniles of Japanese sea bass Lateolabrax japonicus
Published in Marine pollution bulletin (30-08-2014)“…•Estrogen at very low concentration significantly affected the endocrine system in different age group of sea bass.•Under exposure to estrogen…”
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Journal Article Conference Proceeding -
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Benzo[a]pyrene modulates the biotransformation, DNA damage and cortisol level of red sea bream challenged with lipopolysaccharide
Published in Marine pollution bulletin (30-08-2014)“…•Lipopolysaccharide induced the cortisol level in liver of P. major.•BaP increased the cortisol level, EROD activity and hepatic DNA damage of P…”
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Journal Article Conference Proceeding -
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Substrates with patterned topography reveal metastasis of human cancer cells
Published in Biomedical materials (Bristol) (21-08-2017)“…In this study, we aimed at studying the effects of engineered and patterned substrates on the migration characteristics of mammalian cancer cell lines. On the…”
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Immunomodulation in the marine gastropod Haliotis diversicolor exposed to benzo( a)pyrene
Published in Chemosphere (Oxford) (01-04-2009)“…It has been reported that environmental pollutants in the aquatic ecosystem could weaken immune competence of organisms. The purpose of the present study was…”
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Antioxidant enzymes from the crab Scylla paramamosain: Gene cloning and gene/protein expression profiles against LPS challenge
Published in Fish & shellfish immunology (01-05-2010)“…Recent studies revealed that antioxidant enzymes play important roles in antioxidant responses caused by metabolic process or pathogen invasion. Catalase is…”
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Medaka fish exhibits longevity gender gap, a natural drop in estrogen and telomere shortening during aging: a unique model for studying sex-dependent longevity
Published in Frontiers in zoology (23-12-2013)“…INTRODUCTION: Females having a longer telomere and lifespan than males have been documented in many animals. Such linkage however has never been reported in…”
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First molecular cloning of a molluscan caspase from variously colored abalone ( Haliotis diversicolor) and gene expression analysis with bacterial challenge
Published in Fish & shellfish immunology (01-04-2010)“…Mammal caspases have been demonstrated to possess important functions in apoptosis and immune signaling, but there is less knowledge available on abalone…”
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