Search Results - "Goosens, Ki A"
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Chronic Stress Alters Striosome-Circuit Dynamics, Leading to Aberrant Decision-Making
Published in Cell (16-11-2017)“…Effective evaluation of costs and benefits is a core survival capacity that in humans is considered as optimal, “rational” decision-making. This capacity is…”
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2
Amygdala-ventral striatum circuit activation decreases long-term fear
Published in eLife (27-09-2016)“…In humans, activation of the ventral striatum, a region associated with reward processing, is associated with the extinction of fear, a goal in the treatment…”
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3
Hippocampal Processing of Ambiguity Enhances Fear Memory
Published in Psychological science (01-02-2017)“…Despite the ubiquitous use of Pavlovian fear conditioning as a model for fear learning, the highly predictable conditions used in the laboratory do not…”
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4
Brain atlas for glycoprotein hormone receptors at single-transcript level
Published in eLife (02-09-2022)“…There is increasing evidence that anterior pituitary hormones, traditionally thought to have unitary functions in regulating single endocrine targets, act on…”
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5
Gene expression changes in the motor cortex mediating motor skill learning
Published in PloS one (24-04-2013)“…The primary motor cortex (M1) supports motor skill learning, yet little is known about the genes that contribute to motor cortical plasticity. Such knowledge…”
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6
A randomized pilot study of the prophylactic effect of ketamine on laboratory-induced stress in healthy adults
Published in Neurobiology of stress (01-01-2023)“…Stress exposure is a key risk factor for the development of major depressive disorder and posttraumatic stress disorder. Enhancing stress resilience in at-risk…”
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7
Context-Dependent Neuronal Activity in the Lateral Amygdala Represents Fear Memories after Extinction
Published in The Journal of neuroscience (10-09-2003)“…The context in which fear memories are extinguished has important implications for treating human fear and anxiety disorders. Extinction of Pavlovian fear…”
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8
Ghrelin as a Stress Hormone: Implications for Psychiatric Illness
Published in Biological psychiatry (1969) (01-10-2020)“…The stress response is an adaptive means of maintaining physiological homeostasis in the face of changing environmental conditions. However, protracted…”
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9
FSH blockade improves cognition in mice with Alzheimer’s disease
Published in Nature (London) (17-03-2022)“…Alzheimer’s disease has a higher incidence in older women, with a spike in cognitive decline that tracks with visceral adiposity, dysregulated energy…”
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10
Sampling blood from the lateral tail vein of the rat
Published in Journal of visualized experiments (18-05-2015)“…Blood samples are commonly obtained in many experimental contexts to measure targets of interest, including hormones, immune factors, growth factors, proteins,…”
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11
Long-term potentiation as a substrate for memory: Evidence from studies of amygdaloid plasticity and Pavlovian fear conditioning
Published in Hippocampus (2002)“…Recent reports have raised concerns about the ability of long‐term potentiation (LTP) to account for associative learning and memory. In this paper, we review…”
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12
The Amygdala Is Essential for the Development of Neuronal Plasticity in the Medial Geniculate Nucleus during Auditory Fear Conditioning in Rats
Published in The Journal of neuroscience (15-03-2001)“…The medial geniculate nucleus of the thalamus (MGN) and the basolateral complex of the amygdala (BLA) are critical components of the neural circuit that…”
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13
Central Ghrelin Resistance Permits the Overconsolidation of Fear Memory
Published in Biological psychiatry (1969) (15-06-2017)“…Abstract Background There are many contradictory findings about the role of the hormone ghrelin in aversive processing, with studies suggesting that ghrelin…”
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14
A role for amygdaloid PKA and PKC in the acquisition of long-term conditional fear memories in rats
Published in Behavioural brain research (01-09-2000)“…Although there is great interest in the cellular mechanisms underlying Pavlovian conditioning, few studies have directly examined the contribution of…”
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15
Input-specific contributions to valence processing in the amygdala
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-10-2016)“…Reward and punishment are often thought of as opposing processes: rewards and the environmental cues that predict them elicit approach and consummatory…”
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16
Ghrelin is a persistent biomarker for chronic stress exposure in adolescent rats and humans
Published in Translational psychiatry (11-04-2018)“…Prolonged stressor exposure in adolescence enhances the risk of developing stress-sensitive mental illnesses, including posttraumatic stress disorder (PTSD),…”
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17
Stress Enables Reinforcement-Elicited Serotonergic Consolidation of Fear Memory
Published in Biological psychiatry (1969) (15-05-2016)“…Abstract Background Prior exposure to stress is a risk factor for developing posttraumatic stress disorder (PTSD) in response to trauma, yet the mechanisms by…”
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18
An atlas of brain-bone sympathetic neural circuits in mice
Published in eLife (04-07-2024)“…There is clear evidence that the sympathetic nervous system (SNS) mediates bone metabolism. Histological studies show abundant SNS innervation of the…”
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Contextual and auditory fear conditioning are mediated by the lateral, basal, and central amygdaloid nuclei in rats
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-05-2001)“…A large body of literature implicates the amygdala in Pavlovian fear conditioning. In this study, we examined the contribution of individual amygdaloid nuclei…”
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20
NMDA receptors are essential for the acquisition, but not expression, of conditional fear and associative spike firing in the lateral amygdala
Published in The European journal of neuroscience (01-07-2004)“…We examined the contribution of N‐methyl‐D‐aspartate (NMDA) receptors (NMDARs) to the acquisition and expression of amygdaloid plasticity and Pavlovian fear…”
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