Search Results - "Goonasekara, Charitha L."

Medicinal plants commonly used against cancer in traditional medicine formulae in Sri Lanka by Kuruppu, Anchala I., Paranagama, Priyani, Goonasekara, Charitha L.

“…Cancer is a global burden. In low- and middle-income countries around 70% of deaths are due to cancer. For a number of years natural products have been a good…”
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Natural antibody responses to the capsid protein in sera of Dengue infected patients from Sri Lanka by Nadugala, Mahesha N, Jeewandara, Chandima, Malavige, Gathsaurie N, Premaratne, Prasad H, Goonasekara, Charitha L

“…This study aims to characterize the antigenicity of the Capsid (C) protein and the human antibody responses to C protein from the four dengue virus (DENV)…”
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Medicinal Plants Used in Sri Lankan Traditional Medicine for Dengue Fever by Handagala, Jayani K., Kumarasinghe, Nishantha, Goonasekara, Charitha L., Kuruppu, Anchala I.

“…Dengue fever, a mosquito-borne viral infectious disease caused by the dengue virus, is a significant global health concern, especially in tropical and…”
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Natural immunogenic properties of bioinformatically predicted linear B-cell epitopes of dengue envelope and pre-membrane proteins by Nadugala, Mahesha N, Jeewandara, Chandima, Jadi, Ramesh S, Malavige, Gathsaurie N, de Silva, Aravinda M, Premaratne, Prasad H, Goonasekara, Charitha L

“…The natural antibody responses to B-cell epitopes from dengue structural proteins were assessed using immune sera from people having well-defined past dengue…”
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Characterization of Daboia russelii and Naja naja venom neutralizing ability of an undocumented indigenous medication in Sri Lanka by Silva, Madhushika M., Seneviratne, Sampath S., Weerakoon, Devaka K., Goonasekara, Charitha L.

“…Indigenous medicinal practice in Sri Lanka talks about powerful compounds extracted from native plants for treating venomous snake bites which are hardly…”
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Systematic Bioinformatic Approach for Prediction of Linear B-Cell Epitopes on Dengue E and prM Protein by Nadugala, Mahesha N., Premaratne, Prasad H., Goonasekara, Charitha L.

“…B-cell epitopes on the envelope (E) and premembrane (prM) proteins of dengue virus (DENV) were predicted using bioinformatics tools, BepiPred, Ellipro, and…”
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Further Investigation into the Biochemical Effects of Phosphorylation of Tropomyosin Tpm1.1(α). Serine-283 Is in Communication with the Midregion by Silva, A. Madhushika M, Goonasekara, Charitha L, Hayley, Michael, Heeley, David H

“…The phosphorylated and unphosphorylated forms of tropomyosin Tpm1.1­(α) are prepared from adult rabbit heart and compared biochemically. Electrophoresis…”
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Threonine-77 Is a Determinant of the Low-Temperature Conditioning of the Most Abundant Isoform of Tropomyosin in Atlantic Salmon by Silva, A. Madhushika M, Ige, Tolulope, Goonasekara, Charitha L, Heeley, David H

“…The Atlantic salmon Salmo salar survives below 10 °C. The main skeletal muscle is composed of a single isoform of tropomyosin (classified as Tpm1 α-fast) that…”
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Ethnopharmacological Use and Biological Activities of Tragia involucrata L. by Arawwawala, Menuka, Kumarasinghe, Nishantha, Perera, Pathirage Kamal, Pallie, Mumtaz S., Goonasekara, Charitha L.

“…Plants have been utilized as medicines to treat various ailments since ancient times. Formulations made by plant materials have been used in traditional,…”
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Cholesterol and cardiac arrhythmias by Goonasekara, Charitha L, Balse, Elise, Hatem, Stephan, Steele, David F, Fedida, David

“…Cardiac arrhythmias are a leading cause of morbidity and mortality in the Western world. Ventricular arrhythmias are reportedly responsible for the majority of…”
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Effect of Removing the Amino-Terminal Hexapeptide of Tropomyosin on the Properties of the Thin Filament by Goonasekara, Charitha L, Heeley, David H

“…The role of the amino-terminal region of α-striated muscle tropomyosin has been analyzed by reconstituting thin filaments with a version of the protein lacking…”
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Normal targeting of a tagged Kv1.5 channel acutely transfected into fresh adult cardiac myocytes by a biolistic method by Dou, Ying, Balse, Elise, Dehghani Zadeh, Alireza, Wang, Tiantian, Goonasekara, Charitha L, Noble, Geoffrey P, Eldstrom, Jodene, Steele, David F, Hatem, Stéphane N, Fedida, David

“…The transfection of cardiac myocytes is difficult, and so most of the data regarding the regulation of trafficking and targeting of cardiac ion channels have…”
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Conformational properties of striated muscle tropomyosins from some salmonid fishes by Goonasekara, Charitha L., Heeley, David H.

“…The conformational stability of tropomyosins from salmonids fishes has been investigated under a variety of conditions (salt, pH and osmolyte) using electronic…”
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Some binding properties of Omp T digested muscle tropomyosin by Goonasekara, Charitha L, Gallivan, Lisa J, Jackman, Donna M, Heeley, David H

“…Cleavage of vertebrate muscle tropomyosin by bacterial Omp T produces an amino-terminally truncated product (residues 7-284). The proteolysed protein, which is…”
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The Binding of S1A1-ADP to Skeletal Thin Filaments is Insensitive to the Presence of Covalently Bound Phosphate in Tropomyosin by Heeley, David H., Goonasekara, Charitha L., Howard, White D.

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Efficient Biolistic Transfection of Fresh Adult Cardiac Myocytes with a Tagged Kv1.5 Channel by Wang, Tiantian, Zadeh, Alireza D., Dou, Ying, Goonasekara, Charitha L., Steele, David F., Fedida, David

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