Search Results - "Gooijer, C.D. de"

Dynamic modeling of immobilized Nitrosomonas europaea: Implementation of diffusion limitation over expanding microcolonies by Wijffels, R.H., de Gooijer, C.D., Schepers, A.W., Beuling, E.E., Mallée, L.F., Tramper, J.

“…A dynamic model (pseudohomogeneous growth model) describing growth and substrate consumption of immobilized Nitrosomonas europaea resulted in predictions for…”
Get full text

Determination of amino acids using o-phthalaldehyde-2-mercaptoethanol derivatization effect of reaction conditions by Dorresteijn, R.C., Berwald, L.G., Zomer, G., de Gooijer, C.D., Wieten, G., Beuvery, E.C.

“…This paper presents a systematic approach to determine the optimal reaction conditions, with respect to accuracy and sensitivity, of the quantitative…”
Get full text

effect of process conditions on the alpha-amylolytic hydrolysis of amylopectin potato starch: an experimental design approach by Marchal, L.M, Jonkers, J, Franke, G.T, Gooijer, C.D. de, Tramper, J

“…The hydrolysis of amylopectin potato starch with Bacillus licheniformis alpha-amylase (Maxamyl) was studied under industrially relevant conditions (i.e. high…”
Get full text

Bioreactors in series: An overview of design procedures and practical applications by de Gooijer, Cornelis D., Bakker, Wilfried A.M., Beeftink, Hendrik H., Tramper, Johannes

“…“If one fermenter gives good results, two fermenters will give better results and three fermenters better still. This is sometimes true, but often false.”…”
Get full text

Effect of Low Inoculation Density in the Scale-Up of Insect Cell Cultures by Marteijn, R. C. L., Oude-Elferink, M. M. A., Martens, D. E., de Gooijer, C. D., Tramper, J.

“…The scale‐up of insect cell cultures and the production of baculovirus with these cultures is dependent on the inoculation density applied. The effect of…”
Get full text

Design of aqueous two-phase systems supporting animal cell growth: A first step toward extractive bioconversions by Zijlstra, G.M., de Gooijer, C.D., van der Pol, L.A., Tramper, J.

“…The design of aqueous two-phase systems (ATPSs) which support the long-term growth of animal cells is described in this paper. It was found that the increase…”
Get full text

On-line estimation of the biomass activity during animal-cell cultivations by Dorresteijn, R.C, Harbrink Numan, K, Gooijer, C.D. de, Tramper, J, Beuvery, E.C

“…A software sensor was developed to determine the volumetric biomass activity of animal cell cultivations on-line. It was based on the on-line estimation of the…”
Get full text

Hybridoma and CHO Cell Partitioning in Aqueous Two-Phase Systems by Zijlstra, Gerben M., Michielsen, Marco J. F., de Gooijer, Cornelis D., van der Pol, Leo A., Tramper, Johannes

“…The partitioning of mouse/mouse hybridoma cell line BIF6A7, mouse/rat hybridoma PFU‐83, and CHO DUKX B11‐derived cell line BIC‐2 in aqueous two‐phase systems…”
Get full text

On-line control of an immobilized hybridoma culture with multi-channel flow injection analysis by van der Pol, Jens J., Joksch, Burkhard, Galgens, Jochem, Biselli, Manfred, de Gooijer, Cornells D., Tramper, Johannes, Wandrey, Christian

“…An immobilized hybridoma cell line was cultivated at controlled glucose and glutamine concentrations. On-line analysis of the substrates was carried out with a…”
Get full text

Continuous production of baculovirus in a cascade of insect cell reactors by Lier, F.L.J. van, End, E.J. van den, Gooijer, C.D. de, Vlak, J.M, Tramper, J

“…Insect cells (Spodoptera frugiperda) were cultured in a continuous stirred-tank reactor. The effluent was led to a cascade of another two reactors, each…”
Get full text

model for baculovirus production with continuous insect cell cultures by Gooijer, C.D. de, Lier, F.L.J. van, End, E.J. van den, Vlak, J.M, Tramper, J

“…A model, suitable for reactor-design purposes, is presented for the infection process of insect cells with baculovirus in a continuous bioreactor system. The…”
Get full text

Metabolic flux analysis of hybridoma cells in different culture media using mass balances by Bonarius, Hendrik P. J., Hatzimanikatis, Vassily, Meesters, Koen P. H., de Gooijer, Cornelis D., Schmid, Georg, Tramper, Johannes

“…The estimation of the intracellular fluxes of mammalian cells using only the mass balances of the relevant metabolites is not possible because the set of…”
Get full text

Optimization of a feed medium for fed-batch culture of insect cells using a genetic algorithm by Marteijn, R. C. L., Jurrius, O., Dhont, J., de Gooijer, C. D., Tramper, J., Martens, D. E.

“…Insect cells have been cultured for over 30 years, but their application is still hampered by low cell densities in batch fermentations and expensive culture…”
Get full text

Rational medium design for Bordetella pertussis: basic metabolism by Thalen, Marcel, van den IJssel, Jan, Jiskoot, Wim, Zomer, Bert, Roholl, Paul, de Gooijer, Cornelis, Beuvery, Coen, Tramper, Johannes

“…In current Bordetella pertussis media ammonium accumulates because of an imbalance in the nitrogen:carbon ratio of the substrates used, which is one of the…”
Get full text

Extractive bioconversions in aqueous two-phase systems by Zijlstra, Gerben M, de Gooijer, Cornelis D, Tramper, Johannes

“…Although extractive bioconversions in aqueous two-phase systems (ATPSs) have been studied for over a decade, this has not yet resulted in widespread industrial…”
Get full text

Nitrite conversion by immobilized Nitrobacter agilis cells in an air-lift loop bioreactor cascade: Effects of combined substrate and product inhibition by Bakker, Wilfried A.M., Kers, Patrick, Beeftink, Hendrik H., Tramper, Johannes, de Gooijer, Cornelis D.

“…The feasibility of nitrite conversion by immobilized Nitrobacter agilis in an air-lift loop bioreactor cascade was examined. Especially the effects of…”
Get full text

Monte Carlo simulation of the α-amylolysis of amylopectin potato starch. 2. α-amylolysis of amylopectin by MARCHAL, L. M, ULIJN, R. V, DE GOOIJER, C. D, FRANKE, G. T, TRAMPER, J

“…A model is presented that describes all the saccharides that are produced during the hydrolysis of starch by an alpha-amylase. Potato amylopectin, the…”
Get full text

Monte Carlo simulation of the [alpha]-amylolysis of amylopectin potato starch. 2. [alpha]-amylolysis of amylopectin by Marchal, L M, Ulijn, R V, de Gooijer, C D, Franke, G T, Tramper, J

“…A model is presented that describes all the saccharides that are produced during the hydrolysis of starch by an α-amylase. Potato amylopectin, the substrate of…”
Get full text

Activity of glutamate dehydrogenase is increased in ammonia-stressed hybridoma cells by Bonarius, Hendrik P. J., Houtman, José H. M., de Gooijer, Cornelis D., Tramper, Johannes, Schmid, Georg

“…The effect of added ammonia on the intracellular fluxes in hybridoma cells was investigated by metabolic‐flux balancing techniques. It was found that, in…”
Get full text

Determination of amino acids using 0-phthalaldehyde-2-mercaptoethanol derivation. Effect of reaction conditions by Dorresteijn, R.C, Berwald, L.G, Zomer, G, Gooijer, C.D., de, Wieten, G, Beuvery, E.C

Get full text