Search Results - "Goodwin, Zane A"
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Selective sweep for an enhancer involucrin allele identifies skin barrier adaptation out of Africa
Published in Nature communications (07-05-2021)“…The genetic modules that contribute to human evolution are poorly understood. Here we investigate positive selection in the Epidermal Differentiation Complex…”
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Novel Oxytocin Receptor Variants in Laboring Women Requiring High Doses of Oxytocin
Published in American journal of obstetrics and gynecology (01-08-2017)“…Abstract Background Although oxytocin is commonly used to augment or induce labor, it is difficult to predict its effectiveness because oxytocin dose…”
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Recent Positive Selection in Genes of the Mammalian Epidermal Differentiation Complex Locus
Published in Frontiers in genetics (10-01-2017)“…The epidermal differentiation complex (EDC) is the most rapidly evolving locus in the human genome compared to that of the chimpanzee. Yet the EDC genes that…”
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Low filaggrin monomer repeats in African American pediatric patients with moderate to severe atopic dermatitis
Published in JAMA dermatology (Chicago, Ill.) (01-05-2015)Get more information
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Regulation of the Dynamic Chromatin Architecture of the Epidermal Differentiation Complex Is Mediated by a c-Jun/AP-1-Modulated Enhancer
Published in Journal of investigative dermatology (01-09-2014)“…The epidermal differentiation complex (EDC) locus comprises a syntenic and linear cluster of genes whose concomitant expression is a hallmark feature of…”
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