Search Results - "Goodwin, Andrew J"

Exosomes from Endothelial Progenitor Cells Improve the Outcome of a Murine Model of Sepsis by Zhou, Yue, Li, Pengfei, Goodwin, Andrew J., Cook, James A., Halushka, Perry V., Chang, Eugene, Fan, Hongkuan

“…Microvascular dysfunction leads to multi-organ failure and mortality in sepsis. Our previous studies demonstrated that administration of exogenous endothelial…”
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Frequency, Cost, and Risk Factors of Readmissions Among Severe Sepsis Survivors by Goodwin, Andrew J, Rice, David A, Simpson, Kit N, Ford, Dee W

“…OBJECTIVE:To determine the frequency, mortality, cost, and risk factors associated with readmission after index hospitalization with severe sepsis…”
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Suppression of Fli-1 protects against pericyte loss and cognitive deficits in Alzheimer's disease by Li, Pengfei, Wu, Yan, Hamlett, Eric D., Goodwin, Andrew J., Halushka, Perry V., Carroll, Steven L., Liu, Meng, Fan, Hongkuan

“…Brain pericytes regulate cerebral blood flow, maintain the integrity of the blood-brain barrier (BBB), and facilitate the removal of amyloid β (Aβ), which is…”
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Development and implementation of a clinical decision support system-based quality initiative to reduce central line-associated bloodstream infections by Spiegel, Michelle C, Goodwin, Andrew J

“…Central venous lines (CVLs) are frequently utilized in critically ill patients and confer a risk of central line-associated bloodstream infections (CLABSIs)…”
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Exosomes from endothelial progenitor cells improve outcomes of the lipopolysaccharide-induced acute lung injury by Zhou, Yue, Li, Pengfei, Goodwin, Andrew J, Cook, James A, Halushka, Perry V, Chang, Eugene, Zingarelli, Basilia, Fan, Hongkuan

“…The acute respiratory distress syndrome (ARDS) is characterized by disruption of the alveolar-capillary barrier resulting in accumulation of proteinaceous…”
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Circulating extracellular vesicles are associated with the clinical outcomes of sepsis by Li, Pengfei, Wu, Yan, Goodwin, Andrew J, Wolf, Bethany, Halushka, Perry V, Wang, Hongjun, Zingarelli, Basilia, Fan, Hongkuan

“…Sepsis is associated with endothelial cell (EC) dysfunction, increased vascular permeability and organ injury, which may lead to mortality, acute respiratory…”
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A Woman in Her 60s With Fever and Altered Mental Status in a Psychiatric Hospital by Kalivas, Benjamin C., MD, Goodwin, Andrew J., MD

“…A woman in her 60s with a history of hepatitis C with cirrhosis and major depressive disorder with psychotic features was admitted to the inpatient psychiatric…”
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Evaluation of a Telehealth-Enabled Pilot Program to Address Intensive Care Unit Health Care Worker Mental Health Distress by Shah, Nihar, Goodwin, Andrew J., Verdin, Rebecca, Clark, John T., Rheingold, Alyssa A., Ruggiero, Kenneth J., Simpson, Annie N., Ford, Dee W.

“…IntroductionHealth care workers (HCWs) are at heightened risk of adverse mental health events (AMHEs) and burnout with resultant impact on health care…”
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Timing errors and temporal uncertainty in clinical databases-A narrative review by Goodwin, Andrew J, Eytan, Danny, Dixon, William, Goodfellow, Sebastian D, Doherty, Zakary, Greer, Robert W, McEwan, Alistair, Tracy, Mark, Laussen, Peter C, Assadi, Azadeh, Mazwi, Mjaye

“…A firm concept of time is essential for establishing causality in a clinical setting. Review of critical incidents and generation of study hypotheses require a…”
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Self-Assessment of Research Skills and Barriers to Research Careers among Pulmonary and Critical Care Fellows by Scott, Meg K., Goodwin, Andrew J., Nadig, Nandita R., Harvey, Jillian B., Kilb, Edward F.

“…BACKGROUND Recruitment and retention of Pulmonary and Critical Care Medicine (PCCM) trainees into academic research positions remain difficult. Factors…”
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Driving Pressure, Elastance, and Outcomes in a Real-World Setting: A Bi-Center Analysis of Electronic Health Record Data by Goodwin, Andrew J, Brinton, Daniel L, Terry, Charles, Carter, George, Files, D Clark, Kirchoff, Katie, Ford, Dee W, Simpson, Annie N

“…Emerging evidence suggests the potential importance of inspiratory driving pressure (DP) and respiratory system elastance (E ) on outcomes among patients with…”
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An integration engineering framework for machine learning in healthcare by Assadi, Azadeh, Laussen, Peter C., Goodwin, Andrew J., Goodfellow, Sebastian, Dixon, William, Greer, Robert W., Jegatheeswaran, Anusha, Singh, Devin, McCradden, Melissa, Gallant, Sara N., Goldenberg, Anna, Eytan, Danny, Mazwi, Mjaye L.

“…Background and ObjectivesMachine Learning offers opportunities to improve patient outcomes, team performance, and reduce healthcare costs. Yet only a small…”
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Elevated Driving Pressure and Elastance Does Not Increase In-Hospital Mortality Among Obese and Severely Obese Patients With Ventilator Dependent Respiratory Failure by Terry, Charles, Brinton, Daniel, Simpson, Annie N, Kirchoff, Katie, Files, D Clark, Carter, George, Ford, Dee W, Goodwin, Andrew J

“…Existing recommendations for mechanical ventilation are based on studies that under-sampled or excluded obese and severely obese individuals. To determine if…”
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The Impact of Timing on Clinical and Economic Outcomes During Inter-ICU Transfer of Acute Respiratory Failure Patients: Time and Tide Wait for No One by Nadig, Nandita R, Brinton, Daniel L, Simpson, Kit N, Goodwin, Andrew J, Simpson, Annie N, Ford, Dee W

“…Approximately one in 30 patients with acute respiratory failure (ARF) undergoes an inter-ICU transfer. Our objectives are to describe inter-ICU transfer…”
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Successful management of refractory bleeding in liver failure with tranexamic acid: Case report and literature review by Kodali, Saranya, Holmes, Chris E., Tipirneni, Eswar, Cahill, Christina R., Goodwin, Andrew J., Cushman, Mary

“…Unlabelled Box A 50‐year‐old woman with advanced cirrhosis presented with spontaneous subdural hematoma. She had a worsening clinical course following…”
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Can Serial Quick Sequential (Sepsis-Related) Organ Failure Assessment Measurement Aid in Sepsis Identification and Triage Decisions? by Goodwin, Andrew J.

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Fli-1 Governs Pericyte Dysfunction in a Murine Model of Sepsis by Li, Pengfei, Zhou, Yue, Goodwin, Andrew J, Cook, James A, Halushka, Perry V, Zhang, Xian K, Wilson, Carole L, Schnapp, Lynn M, Zingarelli, Basilia, Fan, Hongkuan

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Critical Care Outcomes Among Opioid Users: Hidden Sequelae of a Growing Crisis? by Goodwin, Andrew J.

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Opportunities for microRNAs in the Crowded Field of Cardiovascular Biomarkers by Halushka, Perry V, Goodwin, Andrew J, Halushka, Marc K

“…Cardiovascular diseases exist across all developed countries. Biomarkers that can predict or diagnose diseases early in their pathogeneses can reduce their…”
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Are Sepsis Outcomes Predetermined? How the Road toward Sepsis May Predict Outcomes by Goodwin, Andrew J

“…[...]recent usage patterns may enhance prognostic capabilities in this vulnerable population. [...]the authors' use of latent profile analysis correctly…”
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