Search Results - "Goodstein, Leah"

Mechanically interlocked functionalization of monoclonal antibodies by Bzymek, Krzysztof P., Puckett, James W., Zer, Cindy, Xie, Jun, Ma, Yuelong, King, Jeremy D., Goodstein, Leah H., Avery, Kendra N., Colcher, David, Singh, Gagandeep, Horne, David A., Williams, John C.

“…Because monoclonal antibodies (mAbs) have exceptional specificity and favorable pharmacology, substantial efforts have been made to functionalize them, either…”
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Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag by King, Jeremy D, Ma, Yuelong, Kuo, Yi-Chiu, Bzymek, Krzysztof P, Goodstein, Leah H, Meyer, Kassondra, Moore, Roger E, Crow, Desiree, Colcher, David M, Singh, Gagandeep, Horne, David A, Williams, John C

“…The high specificity and favorable pharmacological properties of monoclonal antibodies (mAbs) have prompted significant interest in re-engineering this class…”
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Engineering a high-affinity peptide binding site into the anti-CEA mAb M5A by Zer, Cindy, Avery, Kendra N., Meyer, Kassondra, Goodstein, Leah, Bzymek, Krzysztof P., Singh, Gagandeep, Williams, John C.

“…Abstract We have previously identified a cyclic peptide called meditope which binds to the central cavity of the Fab portion of cetuximab and shown that this…”
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