Search Results - "Goodrum F"

Human Cytomegalovirus Gene Expression during Infection of Primary Hematopoietic Progenitor Cells: A Model for Latency by Goodrum, Felicia D., Jordan, Craig T., High, Kevin, Shenk, Thomas

“…Human cytomegalovirus (HCMV) resides latently in hematopoietic cells of the bone marrow. Although viral genomes can be found in CD14+ monocytes and CD34+…”
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The early region 1B 55-kilodalton oncoprotein of adenovirus relieves growth restrictions imposed on viral replication by the cell cycle by Goodrum, F D, Ornelles, D A

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p53 Status Does Not Determine Outcome of E1B 55-Kilodalton Mutant Adenovirus Lytic Infection by Goodrum, F D, Ornelles, D A

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Role of organotellurium species in tellurium neuropathy by GOODRUM, J. F

“…Exposure of weanling rats to a diet containing 1% elemental tellurium causes segmental demyelination of peripheral nerve, and an inhibition of squalene…”
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Adenovirus early region 4 34-kilodalton protein directs the nuclear localization of the early region 1B 55-kilodalton protein in primate cells by Goodrum, F D, Shenk, T, Ornelles, D A

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Control of Cholesterol Biosynthesis in Schwann Cells by Fu, Qiang, Goodrum, Jeffry F., Hayes, Carol, Hostettler, Janell D., Toews, Arrel D., Morell, Pierre

“…: Cholesterol accounts for over one‐fourth of total myelin lipids. We found that, during development of the rat sciatic nerve, expression of mRNA for…”
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Axonal Regeneration, but Not Myelination, Is Partially Dependent on Local Cholesterol Reutilization in Regenerating Nerve by GOODRUM, JEFFRY F, BROWN, JUSTIN C, FOWLER, KENNETH A, BOULDIN, THOMAS W

“…A recycling pathway in peripheral nerve permits cholesterol from degenerating myelin to be salvaged by macrophages and resupplied to myelinating Schwann cells…”
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Cholesterol from degenerating nerve myelin becomes associated with lipoproteins containing apolipoprotein E by Goodrum, J F

“…Apolipoprotein E is synthesized and secreted by rat sciatic nerve consequent to several types of injury. It has been proposed that endoneurial apolipoprotein…”
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The Cell Biology of Myelin Degeneration and Regeneration in the Peripheral Nervous System by Goodrum, Jeffry F, Bouldin, Thomas W

“…Keywords: Lipoproteins, Macrophage, Myelin lipids, Peripheral nerve, Schwann cell, Wallerian degeneration…”
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Nerve regeneration occurs in the absence of apolipoprotein E in mice by Popko, B, Goodrum, J F, Bouldin, T W, Zhang, S H, Maeda, N

“…The concentration of apolipoprotein E (apoE), a high-affinity ligand for the low-density lipoprotein receptor, increases dramatically in peripheral nerve…”
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Cholesterol synthesis is down-regulated during regeneration of peripheral nerve by Goodrum, J F

“…The discovery of apolipoprotein E synthesis and secretion by injured peripheral nerve to the hypothesis that endoneurial apolipoprotein E serves to salvage…”
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Roles for the E4 orf6, orf3, and E1B 55-Kilodalton Proteins in Cell Cycle-Independent Adenovirus Replication by Goodrum, F D, Ornelles, D A

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Fate of myelin lipids during degeneration and regeneration of peripheral nerve: an autoradiographic study by Goodrum, JF, Earnhardt, T, Goines, N, Bouldin, TW

“…Four weeks after labeling myelin lipids with an intraneural injection of 3H-acetate, sciatic nerves were crushed, and the distribution of radiolabeled myelin…”
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Cholesterol synthesis in regenerating peripheral nerve is not influenced by serum cholesterol levels by Goodrum, J F

“…Following a nerve crush, cholesterol from degenerating myelin is retained within the nerve and reutilized for new myelin synthesis during nerve regeneration,…”
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Cholesterol reutilization during myelination of regenerating PNS axons is impaired in Niemann-Pick disease type C mice by Goodrum, Jeffry F., Pentchev, Peter G.

“…Niemann‐Pick C (NPC) disease is an autosomal recessive lipidosis characterized by lysosomal accumulations of unesterified cholesterol. Cultured NPC cells…”
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New advances in CMV and immunosenescence by Sansoni, Paolo, Vescovini, Rosanna, Fagnoni, Francesco F., Akbar, Arne, Arens, Ramon, Chiu, Yen-Ling, Čičin-Šain, Luka, Dechanet-Merville, Julie, Derhovanessian, Evelyna, Ferrando-Martinez, Sara, Franceschi, Claudio, Frasca, Daniela, Fulöp, Tamas, Furman, David, Gkrania-Klotsas, Effrossyni, Goodrum, Felicia, Grubeck-Loebenstein, Beatrix, Hurme, Mikko, Kern, Florian, Lilleri, Daniele, López-Botet, Miguel, Maier, Andrea B., Marandu, Thomas, Marchant, Arnaud, Matheï, Catharina, Moss, Paul, Muntasell, Aura, Remmerswaal, Ester B.M., Riddell, Natalie E., Rothe, Kathrin, Sauce, Delphine, Shin, Eui-Cheol, Simanek, Amanda M., Smithey, Megan J., Söderberg-Nauclér, Cecilia, Solana, Rafael, Thomas, Paul G., van Lier, Rene, Pawelec, Graham, Nikolich-Zugich, Janko

“…Immunosenescence, defined as the age-associated dysregulation and dysfunction of the immune system, is characterized by impaired protective immunity and…”
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Nerve regeneration and cholesterol reutilization occur in the absence of apolipoproteins E and A-I in mice by Goodrum, J F, Bouldin, T W, Zhang, S H, Maeda, N, Popko, B

“…Apolipoproteins have been implicated in the salvage and reutilization of myelin cholesterol during Wallerian degeneration and the subsequent nerve…”
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Fatty acids from degenerating myelin lipids are conserved and reutilized for myelin synthesis during regeneration in peripheral nerve by Goodrum, J F, Weaver, J E, Goines, N D, Bouldin, T W

“…Following nerve crush, cholesterol from degenerating myelin is conserved and reutilized for new myelin synthesis during nerve regeneration. The possibility…”
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Neurofilament and tubulin mRNA expression in Schwann cells by Roberson, M D, Toews, A D, Goodrum, J F, Morell, P

“…Feeding of elemental tellurium to weanling rats blocks synthesis of cholesterol (a major component of myelin), and causes demyelination of the sciatic nerve…”
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Peripheral nerve regeneration and cholesterol reutilization are normal in the low-density lipoprotein receptor knockout mouse by Goodrum, Jeffry F., Fowler, Kenneth A., Hostettler, Janell D., oews, Arrel D. T

“…Following peripheral nerve injury, cholesterol from degenerating myelin is retained locally within macrophages and subsequently reutilized by Schwann cells for…”
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