Search Results - "Goodman, P. A"

Expression of Aberrantly Spliced Oncogenic Ikaros Isoforms in Childhood Acute Lymphoblastic Leukemia by LEI SUN, GOODMAN, P. A, SEIBEL, N, VASSILEV, A, JURAN, B. D, REAMAN, G. H, UCKUN, F. M, WOOD, C. M, CROTTY, M.-L, SENSEL, M, SATHER, H, NAVARA, C, NACHMAN, J, STEINHERZ, P. G, GAYNON, P. S

“…We sought to determine if molecular abnormalities involving the Ikaros gene could contribute to the development of acute lymphoblastic leukemia (ALL) in…”
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Rational drug design of multifunctional phosphoramidate substituted nucleoside analogs by Venkatachalam, T K, Goodman, P A, Qazi, S, D'Cruz, O, Uckun, F M

“…This review focuses on our approach to the study of the effect of a series of phosphoramidate substituted nucleoside analogs on model systems for cancer, HIV…”
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Genetics and polymorphism of the mouse prion gene complex: control of scrapie incubation time by CARLSON, G. A, GOODMAN, P. A, LOVETT, M, TAYLOR, B. A, MARSHALL, S. T, PETERSON-TORCHIA, M, WESTAWAY, D, PRUSINER, S. B

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The human insulin gene contains multiple transcriptional elements that respond to glucocorticoids by FERNANDEZ-MEJIA, C, MEDINA-MARTINEZ, O, MARTINEZ-PEREZ, L, GOODMAN, P. A

“…Glucocorticoids inhibit insulin expression in cultured pancreatic islet cells. In this study, we provide evidence that transcriptional downregulation of…”
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Distinct prion proteins in short and long scrapie incubation period mice by Westaway, D, Goodman, P A, Mirenda, C A, McKinley, M P, Carlson, G A, Prusiner, S B

“…The Prn-i gene, controlling scrapie incubation period, is linked to or congruent with the murine prion protein (PrP) gene, Prn-p. In prototypic mouse strains…”
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Identification of the human insulin negative regulatory element as a negative glucocorticoid response element by Goodman, P.A., Medina-Martinez, O., Fernandez-Mejia, C.

“…Insulin gene transcription in adults is restricted to pancreatic beta cells. Studies with both transgenic mice and islet cell lines have demonstrated that beta…”
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Linkage of prion protein and scrapie incubation time genes by Carlson, G A, Kingsbury, D T, Goodman, P A, Coleman, S, Marshall, S T, DeArmond, S, Westaway, D, Prusiner, S B

“…A single gene (Prn-i) that affects scrapie incubation period in mice has been identified. I/LnJ mice have a very long incubation period after inoculation of…”
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Many Protein Products From a Few Loci: Assignment of Human Salivary Proline-Rich Proteins to Specific Loci by Lyons, K. M, Azen, E. A, Goodman, P. A, Smithies, O

“…Earlier studies of protein polymorphisms led to the description of 13 linked loci thought to encode the human salivary proline-rich proteins (PRPs). However,…”
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Human insulin receptor radioimmunoassay: applicability to insulin-resistant states by Pezzino, V, Papa, V, Trischitta, V, Brunetti, A, Goodman, P A, Treutelaar, M K, Williams, J A, Maddux, B A, Vigneri, R, Goldfine, I D

“…A radioimmunoassay of the human insulin receptor was developed employing a potent rabbit polyclonal antibody to the human insulin receptor and a highly…”
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Production of inhibitor of insulin-receptor tyrosine kinase in fibroblasts from patient with insulin resistance and NIDDM by Sbraccia, P., Goodman, P. A., Maddux, B. A., Wong, K. Y., Chen, Y. D., Reaven, G. M., Goldfine, I. D.

“…Production of inhibitor of insulin-receptor tyrosine kinase in fibroblasts from patient with insulin resistance and NIDDM. P Sbraccia , P A Goodman , B A…”
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Spleen tyrosine kinase (Syk) deficiency in childhood pro-B cell acute lymphoblastic leukemia by GOODMAN, Patricia A, WOOD, Carla M, VASSILEV, Alexei, CHEN MAO, UCKUN, Fatih M

“…The cytoplasmic spleen tyrosine kinase (SYK) is a key regulator of signal transduction events, apoptosis and orderly cell cycle progression in B-lineage…”
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Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia by GOODMAN, Patricia A, BURKHARDT, Nicole, JURAN, Brian, TIBBLES, Heather E, UCKUN, Faith M

“…Sequence analysis of the noncoding first exon (exon 1) of the Syk gene demonstrated the presence of a previously cloned CpG island (GenBank #Z 65706)…”
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Human salivary proline-rich protein genes on chromosome 12 by AZEN, E. A, GOODMAN, P. A, LALLEY, P. A

“…A DNA probe (PRP1) for the proline-rich protein (PRP) genes was used to analyze the segregation of human PRP genes in human X mouse somatic cell hybrids…”
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Role of tyrosine kinases in induction of the c-jun proto-oncogene in irradiated B-lineage lymphoid cells by Goodman, P A, Niehoff, L B, Uckun, F M

“…Exposure of B-lineage lymphoid cells to ionizing radiation induces an elevation of c-jun proto-oncogene mRNA levels. This signal is abrogated by…”
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Substrate and product inhibition in the xanthine oxidase catalyzed oxidation of acetaldehyde by Goodman, P. A, Meany, J. E

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The human salivary protein complex (SPC): a large block of related genes by Goodman, P A, Yu, P L, Azen, E A, Karn, R C

“…We have shown that genes for at least six human parotid proteins, parotid acidic protein (Pa), proline-rich protein (Pr), double-banded protein (Db),…”
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Genomic Studies of the Spleen Protein Tyrosine Kinase Locus Reveal a Complex Promoter Structure and Several Genetic Variants by Goodman, Patricia A., Juran, Brian, Wood, Carla M., Uckun, Fatih

“…Here we show that the gene of the cytoplasmic tyrosine kinase SYK spans a region of 90 kb with 13 coding exons, an alternative exon 14 and at least two 5'…”
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Jak3 Expression and Genomic Sequence in Pediatric Acute Lymphoblastic Leukemia by Wood, Carla M., Goodman, Patricia A., Uckun, Faith M.

“…Janus tyrosine kinase 3 (JAK3) is one of several key regulatory enzymes in B-cell precursors which is highly conserved between multiple species. The gene for…”
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Human parotid proline-rich proteins: correlation of genetic polymorphisms to dental caries by Yu, P L, Bixler, D, Goodman, P A, Azen, E A, Karn, R C

“…Parotid saliva contains a variety of proline-rich proteins. This study found that, among 306 children between the ages of 5 to 15 years, there is a significant…”
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Better histopathologic technique by Goodman, P A, Bernstein, J

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