Search Results - "Goodman, L S"

Effects of synthetic micro- and nano-structured surfaces on cell behavior by Flemming, R.G., Murphy, C.J., Abrams, G.A., Goodman, S.L., Nealey, P.F.

“…Topographical cues, independent of biochemistry, generated by the extracellular matrix may have significant effects upon cellular behavior. Studies have…”
Get full text

Immunohistochemical screening for β6-integrin subunit expression in adenocarcinomas using a novel monoclonal antibody reveals strong up-regulation in pancreatic ductal adenocarcinomas in vivo and in vitro by Sipos, B, Hahn, D, Carceller, A, Piulats, J, Hedderich, J, Kalthoff, H, Goodman, S L, Kosmahl, M, Klöppel, G

“…Aims : To analyse the expression of αvβ6, an epithelial integrin involved in wound healing and tumorigenesis, in various human carcinoma types. Methods and…”
Get full text

Nanoscale topography of the basement membrane underlying the corneal epithelium of the rhesus macaque by Abrams, G A, Goodman, S L, Nealey, P F, Franco, M, Murphy, C J

“…This paper quantitatively defines the nanoscale topography of the basement membrane underlying the anterior corneal epithelium of the macaque. Excised corneal…”
Get full text

Glycosylated RGD-Containing Peptides: Tracer for Tumor Targeting and Angiogenesis Imaging with Improved Biokinetics by Haubner, Roland, Wester, Hans-Jurgen, Burkhart, Fred, Senekowitsch-Schmidtke, Reingard, Weber, Wolfgang, Goodman, Simon L, Kessler, Horst, Schwaiger, Markus

“…The alpha(v)beta3 integrin plays an important role in metastasis and tumor-induced angiogenesis. Targeting with radiolabeled ligands of the alpha(v)beta3…”
Get full text

Distinctive role of integrin-mediated adhesion in TNF-induced PKB/Akt and NF-κB activation and endothelial cell survival by BIELER, G, HASMIM, M, LEJEUNE, F, ROEGG, C, MONNIER, Y, IMAIZUMI, N, AMEYAR, M, BAMAT, J, PONSONNET, L, CHOUAIB, S, GRELL, M, GOODMAN, S. L

“…Tumor necrosis factor (TNF) is a pro-inflammatory cytokine exerting pleiotropic effects on endothelial cells. Depending on the vascular context it can induce…”
Get full text

Nanoscale Topography of the Corneal Epithelial Basement Membrane and Descemet's Membrane of the Human by Abrams, G A, Schaus, S S, Goodman, S L, Nealey, P F, Murphy, C J

“…PURPOSE.Quantitatively define and compare the nanoscale topography of the corneal epithelial basement membrane (anterior basement membrane) and Descemet's…”
Get full text

Integrins, cations and ligands: making the connection by Xiong, J‐P., Stehle, T., Goodman, S. L., Arnaout, M. A.

“…Integrins are cell adhesion receptors that couple extracellular divalent cation‐dependent recognition events with intracellular mechanical and biochemical…”
Get full text

3-Dimensional Submicron Polymerization of Acrylamide by Multiphoton Excitation of Xanthene Dyes by Campagnola, Paul J, Delguidice, David M, Epling, Gary A, Hoffacker, Kurt D, Howell, Amy R, Pitts, Jonathan D, Goodman, Steven L

“…The two-photon excited (TPE) polymerization of acrylamide using several xanthene sensitizers was studied. Minimum feature sizes in the range of 500 nm were…”
Get full text

Three-dimensional extracellular matrix textured biomaterials by Goodman, Steven L., Sims, Paul A., Albrecht, Ralph M.

“…Clinical and experimental investigations have reported that manufactured surface topographies have significant effects on cell adhesion and tissue integration…”
Get full text

The E8 Subfragment of Laminin Promotes Locomotion of Myoblasts over Extracellular Matrix by Goodman, Simon L., Risse, Gundula, von der Mark, Klaus

“…The locomotion of murine myoblasts over the extracellular matrix components laminin and fibronectin was analyzed using quantitative videomicroscopy, and the…”
Get full text

N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists by Dechantsreiter, M A, Planker, E, Mathä, B, Lohof, E, Hölzemann, G, Jonczyk, A, Goodman, S L, Kessler, H

“…The alpha(V)beta(3) integrin receptor plays an important role in human tumor metastasis and tumor-induced angiogenesis. The in vivo inhibition of this receptor…”
Get full text

Design, synthesis and biological evaluation of nonpeptide integrin antagonists by Nicolaou, K.C., Trujillo, John I., Jandeleit, Bernd, Chibale, Kelly, Rosenfeld, M., Diefenbach, B., Cheresh, D.A., Goodman, S.L.

“…Recent studies demonstrated that peptide and antibody antagonists of integrin α vβ 3 block angiogenesis and tumor growth. In this article, the design,…”
Get full text

Right ventricular hypertrophy detected by echocardiography in patients with newly diagnosed obstructive sleep apnea by Berman, E J, DiBenedetto, R J, Causey, D E, Mims, T, Conneff, M, Goodman, L S, Rollings, R C

“…We used polysomnography, echocardiography and ventilatory measurements to study 50 patients suspected of having OSA to determine a link to RVH. Twenty-eight…”
Get more information

Skeletal myoblasts utilize a novel beta 1-series integrin and not alpha 6 beta 1 for binding to the E8 and T8 fragments of laminin by von der Mark, H, Dürr, J, Sonnenberg, A, von der Mark, K, Deutzmann, R, Goodman, S L

“…The E8 fragment of laminin stimulates myoblast attachment and locomotion. Myoblast attachment to laminin/E8 was blocked by anti-integrin antibodies against…”
Get full text

Two Distinct Cell-Binding Domains in Laminin Can Independently Promote Nonneuronal Cell Adhesion and Spreading by Goodman, Simon L., Deutzmann, Rainer, von der Mark, Klaus

“…Two subfragments of laminin, E8, a major part of the long arm, and E1-4, the three short arms, promote cell adhesion and spreading. Three distinct types of…”
Get full text

Surface Coating with Cyclic RGD Peptides Stimulates Osteoblast Adhesion and Proliferation as well as Bone Formation by Kantlehner, Martin, Schaffner, Patricia, Finsinger, Dirk, Meyer, Jörg, Jonczyk, Alfred, Diefenbach, Beate, Nies, Berthold, Hölzemann, Günter, Goodman, Simon L., Kessler, Horst

“…The physiological inertness of synthetic implant materials often results in insufficient implant integration and limited acceptance of implants in tissues…”
Get full text

Considering Conservation Value in Economic Appraisals of Coastal Resources by Goodman, S. L., Seabrooke, W., Jaffry, S. A.

“…Measuring the economic value of environmental quality is useful to evaluate policies that affect the use of natural resources. This paper presents the findings…”
Get full text

Neovascular targeting with cyclic RGD peptide (cRGDf-ACHA) to enhance delivery of radioimmunotherapy by DeNardo, S J, Burke, P A, Leigh, B R, O'Donnell, R T, Miers, L A, Kroger, L A, Goodman, S L, Matzku, S, Jonczyk, A, Lamborn, K R, DeNardo, G L

“…Radioimmunotherapy (RIT) has been hampered by delivery of only a small fraction of the administered dose of radiolabeled MAb to tumor. A strategy for creating…”
Get more information

Dissociation of Madin-Darby Canine Kidney Epithelial Cells by the Monoclonal Antibody Anti-Arc-1: Mechanistic Aspects and Identification of the Antigen as a Component Related to Uvomorulin by Behrens, Jürgen, Birchmeier, Walter, Goodman, Simon L., Imhof, Beat A.

“…It has previously been shown that the monoclonal antibody anti-Arc-1 dissociates Madin-Darby canine kidney (MDCK) epithelial cells and changes their morphology…”
Get full text

Multiple cell surface receptors for the short arms of laminin: alpha 1 beta 1 integrin and RGD-dependent proteins mediate cell attachment only to domains III in murine tumor laminin by Goodman, S L, Aumailley, M, von der Mark, H

“…Cell surface molecules that interact with the cross formed by the three short arms of murine tumor laminin were studied using thermal perturbation, antibody…”
Get full text