Search Results - "Goodman, Carl B"

Selective Cytotoxic Activities of Two Novel Synthetic Drugs on Human Breast Carcinoma MCF-7 Cells by BADISA, Ramesh B, DARLING-REED, Selina F, JOSEPH, Patrick, COOPERWOOD, John S, LATINWO, Lekan M, GOODMAN, Carl B

“…Background: Breast cancer is the second leading cause of cancer deaths in US women. We evaluated two novel compounds, piperidinyl-diethylstilbestrol (DES) and…”
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Identification of biochemical and cytotoxic markers in cocaine treated PC12 cells by Badisa, Ramesh B., Batton, Chyree S., Mazzio, Elizabeth, Grant, Samuel C., Goodman, Carl B.

“…Cocaine is one of the powerful addictive drugs, widely abused in most Western countries. Because of high lipophilic nature, cocaine easily reaches various…”
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Identification of cytotoxic markers in methamphetamine treated rat C6 astroglia-like cells by Badisa, Ramesh B., Wiley, Chantel, Randell, Kesa, Darling-Reed, Selina F., Latinwo, Lekan M., Agharahimi, Maryam, Soliman, Karam F. A., Goodman, Carl B.

“…Methamphetamine (METH) is a powerfully addictive psychostimulant that has a pronounced effect on the central nervous system (CNS). The present study aimed to…”
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N-acetyl cysteine mitigates the acute effects of cocaine-induced toxicity in astroglia-like cells by Badisa, Ramesh B, Kumar, Sanjay S, Mazzio, Elizabeth, Haughbrook, Rasheda D, Allen, John R, Davidson, Michael W, Fitch-Pye, Cheryl A, Goodman, Carl B

“…Cocaine has a short half-life of only about an hour but its effects, predominantly on the central nervous system (CNS), are fairly long-lasting. Of all cells…”
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Cellular and molecular responses to acute cocaine treatment in neuronal-like N2a cells: potential mechanism for its resistance in cell death by Badisa, Ramesh B., Wi, Sungsool, Jones, Zachary, Mazzio, Elizabeth, Zhou, Yi, Rosenberg, Jens T., Latinwo, Lekan M., Grant, Samuel C., Goodman, Carl B.

“…Cocaine is a highly abused drug that causes psychiatric and neurological problems. Its entry into neurons could alter cell-biochemistry and contribute in the…”
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Cocaine Induces Alterations in Mitochondrial Membrane Potential and Dual Cell Cycle Arrest in Rat C6 Astroglioma Cells by Badisa, Ramesh B., Darling-Reed, Selina F., Goodman, Carl B.

“…Investigations with astroglial cells carry more prominence in drug abuse studies. However, due to earlier perception that astroglial cells were only passive…”
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Anti-inflammatory effects of thymoquinone in activated BV-2 microglial cells by Taka, Equar, Mazzio, Elizabeth A, Goodman, Carl B, Redmon, Natalie, Flores-Rozas, Hernan, Reams, Renee, Darling-Reed, Selina, Soliman, Karam F.A

“…Abstract Thymoquinone (TQ), the main pharmacological active ingredient within the black cumin seed ( Nigella sativa ) is believed to be responsible for the…”
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Anaerobic glycolysis protection against 1-methy-4-phenylpyridinium (MPP+) toxicity in C6 glioma cells by Williams, Zakia R, Goodman, Carl B, Soliman, Karam F A

“…The neurotoxin 1-methy-4-phenylpyridinium (MPP(+)) is used for its' capacity to induce Parkinsonism through its inhibitory effects on mitochondrial complex I…”
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Autoxidation of gallic acid induces ROS-dependent death in human prostate cancer LNCaP cells by Russell, Jr, Larry H, Mazzio, Elizabeth, Badisa, Ramesh B, Zhu, Zhi-Ping, Agharahimi, Maryam, Oriaku, Ebenezer T, Goodman, Carl B

“…Prostate cancer is the second most common cause of mortality. Gallic acid (GA) is a natural polyphenol, and we tested its in-vitro cytotoxicity after 24 h in…”
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Autoxidation of Gallic Acid Induces ROS-dependant Death in Human Prostate Cancer LNCaP Cells by RUSSELL, Larry H, MAZZIO, Elizabeth, BADISA, Ramesh B, ZHU, Zhi-Ping, AGHARAHIMI, Maryam, ORIAKU, Ebenezer T, GOODMAN, Carl B

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Substituted Tetrahydroisoquinolines as Microtubule-destabilizing Agents in Triple Negative Human Breast Cancer Cells by Gangapuram, Madhavi, Jean, Riccardo, Mazzio, Elizabeth, Badisa, Ramesh, Eyunni, Suresh, Goodman, Carl B, Redda, Kinfe K, Soliman, Karam F

“…Triple-negative breast cancer (TNBC) occurs at greater frequency amongst African-Americans, being characterized by the absence of estrogen receptor (ER),…”
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Cocaine potentiates an inflammatory response in C6 astroglia-like cells by Agharahimi, Maryam, Badisa, Ramesh B, Mazzio, Elizabeth, Soliman, Karam F, Goodman, Carl B

“…Cocaine is a highly addictive drug that mediates its effect through altering dopamine metabolism in the central nervous system (CNS), resulting in a feeling of…”
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Effects of chronic cocaine in rat C6 astroglial cells by BADISA, RAMESH B, GOODMAN, CARL B

“…Investigations with astroglial cells carry equal importance as those with neurons in drug abuse studies. The present study was aimed to investigate the effect…”
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Attenuating effect of N-acetyl-L-cysteine against acute cocaine toxicity in rat C6 astroglial cells by BADISA, RAMESH B, GOODMAN, CARL B, FITCH-PYE, CHERYL A

“…Astroglial cells are one of the most abundant cell types in the mammalian brain functioning in neuronal survival and in maintenance of fundamental patterns of…”
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Differential Cytotoxicity of Triphala and its Phenolic Constituent Gallic acid on Human Prostate Cancer LNCap and Normal Cells by RUSSELL, Larry H, MAZZIO, Elizabeth, BADISA, Ramesh B, ZHU, Zhi-Ping, AGHARAHIMI, Maryam, MILLINGTON, Donna J, GOODMAN, Carl B

“…Prostate cancer is one of the most commonly diagnosed solid malignancies among US men. We identified gallic acid (GA) as a major bioactive cytotoxic…”
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Regulation of mammalian MOR-1 gene expression after chronic treatment with morphine by PRENUS, ROSE V, LUSCAR, EBENS, ZHU, ZHI-PING, BADISA, RAMESH B, GOODMAN, CARL B

“…Morphine is an effective analgesic that acts by binding to the μ-opioid receptor (MOR) coded in the human by the OPRM1 gene. In the present study, we…”
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Milk thistle seed extract protects rat C6 astroglial cells from acute cocaine toxicity by BADISA, RAMESH B, FITCH-PYE, CHERYL A, AGHARAHIMI, MARYAM, PALM, DONALD E, LATINWO, LEKAN M, GOODMAN, CARL B

“…Cocaine is a powerful addictive drug, widely abused in most Western countries. It easily reaches various domains within and outside of the central nervous…”
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Regulation of rat MOR-1 gene expression after chronic intracerebroventricular administration of morphine by Zhu, Zhi-Ping, Badisa, Ramesh B, Palm, Donald E, Goodman, Carl B

“…The µ-opioid receptor is the primary site for the action of morphine. In the present study, we investigated the regulation of the µ-opioid receptor mRNA levels…”
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Comparative proteomic analysis reveals growth inhibition by 3-N-alkyloxyestradiol derivative (SERM) in prostate cancer cells by Green, Jennifer E, Cooperwood, John S, Taka, Equar, Soliman, Karam Fa, Goodman, Carl B, Reams, Romonia Renee

“…In this study we evaluated the proteomic profile of PC-3 cells treated with novel, 3-N-alkyloxyestradiol derivative, 3-[2-diisopropylamino]-ethoxy-D1,3,5…”
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Hydrogen peroxide induces lysosomal protease alterations in PC12 cells by Lee, Daniel C, Mason, Ceceile W, Goodman, Carl B, Holder, Maurice S, Kirksey, Otis W, Womble, Tracy A, Severs, Walter B, Palm, Donald E

“…Alterations in lysosomal proteases have been implicated in many neurodegenerative diseases. The current study demonstrates a concentration-dependent decrease…”
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