Search Results - "Goodman, Asha Z"
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Mice lacking cyclophilin B, but not cyclophilin A, are protected from the development of NASH in a diet and chemical-induced model
Published in PloS one (01-03-2024)“…Cyclophilins are a diverse family of peptidyl-prolyl isomerases (PPIases) of importance in a variety of essential cellular functions. We previously reported…”
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Cyclophilin inhibition as a strategy for the treatment of human disease
Published in Frontiers in pharmacology (08-07-2024)“…Cyclophilins (Cyps), characterized as peptidyl-prolyl isomerases (PPIases), are highly conserved and ubiquitous, playing a crucial role in protein folding and…”
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Emergent community architecture despite distinct diversity in the global whale shark (Rhincodon typus) epidermal microbiome
Published in Scientific reports (07-08-2023)“…Microbiomes confer beneficial physiological traits to their host, but microbial diversity is inherently variable, challenging the relationship between microbes…”
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Stingray epidermal microbiomes are species-specific with local adaptations
Published in Frontiers in microbiology (02-03-2023)“…Marine host-associated microbiomes are affected by a combination of species-specific (e.g., host ancestry, genotype) and habitat-specific features (e.g.,…”
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Phage Diving: An Exploration of the Carcharhinid Shark Epidermal Virome
Published in Viruses (01-09-2022)“…The epidermal microbiome is a critical element of marine organismal immunity, but the epidermal virome of marine organisms remains largely unexplored. The…”
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Epidermal Microbiomes of Leopard Sharks ( Triakis semifasciata ) Are Consistent across Captive and Wild Environments
Published in Microorganisms (Basel) (01-10-2022)“…Characterizations of shark-microbe systems in wild environments have outlined patterns of species-specific microbiomes; however, whether captivity affects…”
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The androgen receptor regulates a druggable translational regulon in advanced prostate cancer
Published in Science translational medicine (31-07-2019)“…The androgen receptor (AR) is a driver of cellular differentiation and prostate cancer development. An extensive body of work has linked these normal and…”
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Denaturant-specific effects on the structural energetics of a protein-denatured ensemble
Published in European biophysics journal (01-01-2018)“…Protein thermodynamic stability is intricately linked to cellular function, and altered stability can lead to dysfunction and disease. The linear extrapolation…”
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