Search Results - "Goodison, Steve"

Molecular Profiles of Matched Primary and Metastatic Tumor Samples Support a Linear Evolutionary Model of Breast Cancer by Chen, Runpu, Goodison, Steve, Sun, Yijun

“…The interpretation of accumulating genomic data with respect to tumor evolution and cancer progression requires integrated models. We developed a computational…”
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Prognostic cancer gene signatures share common regulatory motifs by Wang, Ying, Goodison, Steve, Li, Xiaoman, Hu, Haiyan

“…Scientists have discovered various prognostic gene signatures (GSs) in different cancer types. Surprisingly, although different GSs from the same cancer type…”
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Expression of CXCL1 in human endothelial cells induces angiogenesis through the CXCR2 receptor and the ERK1/2 and EGF pathways by Miyake, Makito, Goodison, Steve, Urquidi, Virginia, Gomes Giacoia, Evan, Rosser, Charles J

“…Endothelial cell growth and proliferation are critical for angiogenesis; thus, greater insight into the regulation of pathological angiogenesis is greatly…”
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A multi-analyte assay for the non-invasive detection of bladder cancer by Goodison, Steve, Chang, Myron, Dai, Yunfeng, Urquidi, Virginia, Rosser, Charles J

“…Accurate urinary assays for bladder cancer (BCa) detection would benefit both patients and healthcare systems. Through genomic and proteomic profiling of urine…”
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Matrix metalloproteinase-10 promotes tumor progression through regulation of angiogenic and apoptotic pathways in cervical tumors by Zhang, Ge, Miyake, Makito, Lawton, Adrienne, Goodison, Steve, Rosser, Charles J

“…Cancer invasion and metastasis develops through a series of steps that involve the loss of cell to cell and cell to matrix adhesion, degradation of…”
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Targeting plasminogen activator inhibitor-1 inhibits angiogenesis and tumor growth in a human cancer xenograft model by Gomes-Giacoia, Evan, Miyake, Makito, Goodison, Steve, Rosser, Charles J

“…Cancers of the urinary bladder result in aggressive and highly angiogenic tumors for which standard treatments have only limited success. Patients with…”
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Diagnostic performance of Oncuria™, a urinalysis test for bladder cancer by Hirasawa, Yosuke, Pagano, Ian, Chen, Runpu, Sun, Yijun, Dai, Yunfeng, Gupta, Amit, Tikhonenkov, Sergei, Goodison, Steve, Rosser, Charles J, Furuya, Hideki

“…Due to insufficient accuracy, urine-based assays currently have a limited role in the management of patients with bladder cancer. The identification of…”
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Feature selection for unsupervised learning through local learning by Yao, Jin, Mao, Qi, Goodison, Steve, Mai, Volker, Sun, Yijun

“…•Feature selection method for unsupervised learning inspired by human learning.•Detected features supporting complex structure not limited to…”
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Bladder Cancer Detection and Monitoring: Assessment of Urine- and Blood-Based Marker Tests by Goodison, Steve, Rosser, Charles J., Urquidi, Virginia

“…Bladder cancer is one of the most prevalent cancers worldwide, but the treatment and management of this disease can be very successful if the disease is…”
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Computational approach to modeling microbiome landscapes associated with chronic human disease progression by Li, Lu, Sohn, Jiho, Genco, Robert J, Wactawski-Wende, Jean, Goodison, Steve, Diaz, Patricia I, Sun, Yijun

“…A microbial community is a dynamic system undergoing constant change in response to internal and external stimuli. These changes can have significant…”
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CCL18 in a multiplex urine-based assay for the detection of bladder cancer by Urquidi, Virginia, Kim, Jeongsoon, Chang, Myron, Dai, Yunfeng, Rosser, Charles J, Goodison, Steve

“…The early detection of bladder cancer (BCa) is pivotal for successful patient treatment and management. Through genomic and proteomic studies, we have…”
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Intravesical ALT-803 and BCG treatment reduces tumor burden in a carcinogen induced bladder cancer rat model; a role for cytokine production and NK cell expansion by Gomes-Giacoia, Evan, Miyake, Makito, Goodison, Steve, Sriharan, Aravindhan, Zhang, Ge, You, Lijing, Egan, Jack O, Rhode, Peter R, Parker, Alexander S, Chai, Karl X, Wong, Hing C, Rosser, Charles J

“…Intravesical Bacillus Calmette-Guérin (BCG) has been shown to induce a specific immunologic response (i.e., activation of IL-2 and effector T-cells), while…”
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PAI-1 leads to G1-phase cell-cycle progression through cyclin D3/cdk4/6 upregulation by Giacoia, Evan Gomes, Miyake, Makito, Lawton, Adrienne, Goodison, Steve, Rosser, Charles J

“…The canonical function of plasminogen activator inhibitor-1 (PAI-1/SERPINE1) is as an inhibitor of urokinase-type plasminogen activator for blood clot…”
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PAI-1 is a potential transcriptional silencer that supports bladder cancer cell activity by Furuya, Hideki, Sasaki, Yuka, Chen, Runpu, Peres, Rafael, Hokutan, Kanani, Murakami, Kaoru, Kim, Nari, Chan, Owen T. M., Pagano, Ian, Dyrskjøt, Lars, Jensen, Jørgen B., Malmstrom, Per-Uno, Segersten, Ulrika, Sun, Yijun, Arab, Abolfazl, Goodarzi, Hani, Goodison, Steve, Rosser, Charles J.

“…The extracellular activity of Plasminogen activator inhibitor-1 (PAI-1) is well described, acting as an inhibitor of tissue plasminogen activator and…”
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Persistent exposure to Mycoplasma induces malignant transformation of human prostate cells by Namiki, Kazunori, Goodison, Steve, Porvasnik, Stacy, Allan, Robert W, Iczkowski, Kenneth A, Urbanek, Cydney, Reyes, Leticia, Sakamoto, Noboru, Rosser, Charles J

“…Recent epidemiologic, genetic, and molecular studies suggest infection and inflammation initiate certain cancers, including those of the prostate. The American…”
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Protein kinase D1 regulates matrix metalloproteinase expression and inhibits breast cancer cell invasion by Eiseler, Tim, Döppler, Heike, Yan, Irene K, Goodison, Steve, Storz, Peter

“…The biological and molecular events that regulate the invasiveness of breast tumour cells need to be further revealed to develop effective therapies that stop…”
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Association of SNPs in the PAI1 Gene with Disease Recurrence and Clinical Outcome in Bladder Cancer by Murakami, Kaoru, Furuya, Hideki, Hokutan, Kanani, Goodison, Steve, Pagano, Ian, Chen, Runpu, Shen, Cheng-Huang, Chan, Michael W Y, Ng, Chi Fai, Kobayashi, Takashi, Ogawa, Osamu, Miyake, Makito, Thornquist, Mark, Shimizu, Yoshiko, Hayashi, Kazukuni, Wang, Zhangwei, Yu, Herbert, Rosser, Charles J

“…Bladder cancer (BCa) is one of the most common cancer types worldwide and is characterized by a high rate of recurrence. In previous studies, we and others…”
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A Novel Aptamer Developed for Breast Cancer Cell Internalization by Zhang, Kejing, Sefah, Kwame, Tang, Lili, Zhao, Zilong, Zhu, Guizhi, Ye, Mao, Sun, Weijia, Goodison, Steve, Tan, Weihong

“…Breast cancer affects one in eight women in the United States, with a mortality rate that is second only to lung cancer. Although chemotherapy is widely used…”
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Vascular Endothelial Growth Factor, Carbonic Anhydrase 9, and Angiogenin as Urinary Biomarkers for Bladder Cancer Detection by Urquidi, Virginia, Goodison, Steve, Kim, Jeongsoon, Chang, Myron, Dai, Yunfeng, Rosser, Charles J

“…Objective To investigate whether elevated urinary levels of vascular endothelial growth factor (VEGF), carbonic anhydrase 9 (CA9), and angiogenin are…”
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Urinary mRNA biomarker panel for the detection of urothelial carcinoma by Urquidi, Virginia, Netherton, Mandy, Gomes-Giacoia, Evan, Serie, Daniel, Eckel-Passow, Jeanette, Rosser, Charles J, Goodison, Steve

“…The early detection of bladder cancer is important as the disease has a high rate of recurrence and progression. The development of accurate, non-invasive…”
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