Search Results - "Goodhill, G. J."
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Induction of epithelial–mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent
Published in Oncogene (01-05-2014)“…Signals from the tumor microenvironment trigger cancer cells to adopt an invasive phenotype through epithelial–mesenchymal transition (EMT). Relatively little…”
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How receptor diffusion influences gradient sensing
Published in Journal of the Royal Society interface (06-01-2015)“…Chemotaxis, or directed motion in chemical gradients, is critical for various biological processes. Many eukaryotic cells perform spatial sensing, i.e. they…”
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How deeply does your mutant sleep? Probing arousal to better understand sleep defects in Drosophila
Published in Scientific reports (13-02-2015)“…The fruitfly, Drosophila melanogaster, has become a critical model system for investigating sleep functions. Most studies use duration of inactivity to measure…”
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Generating controlled molecular gradients in 3D gels
Published in Biotechnology and bioengineering (20-09-2005)“…A new method for producing molecular gradients of arbitrary shape in thin three dimensional gels is described. Patterns are produced on the surface of the gel…”
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Retinotectal maps: molecules, models and misplaced data
Published in Trends in neurosciences (Regular ed.) (01-12-1999)“…The mechanisms underlying the formation of topographic maps in the retinotectal system have long been debated. Recently, members of the Eph and ephrin…”
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Mathematical guidance for axons
Published in Trends in neurosciences (Regular ed.) (01-06-1998)“…Axon guidance by gradients plays an important role in wiring up the developing nervous system. Growth cones seem to sense a concentration difference across…”
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The influence of receptor positioning on chemotactic information
Published in Journal of theoretical biology (07-11-2014)“…Chemotaxis, or gradient following, is important in many biological systems, but suffers from noise. How receptors are positioned on the cell or sensing device…”
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Topography and ocular dominance : a model exploring positive correlations
Published in Biological cybernetics (01-06-1993)“…The map from eye to brain in vertebrates is topographic, i.e., neighbouring points in the eye map to neighbouring points in the brain. In addition, when two…”
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Axon guidance: stretching gradients to the limit
Published in Neural computation (01-04-1998)“…Neuronal growth cones, the sensory-motile structures at the tips of developing axons, navigate to their targets over distances that can be many times greater…”
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Influences on the global structure of cortical maps
Published in Proceedings of the Royal Society. B, Biological sciences (22-05-1997)“…Cortical maps often contain global spatial structure; however, theoretical accounts for their development have generally concentrated on reproducing only local…”
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Stimulating issues in cortical map development
Published in Trends in neurosciences (Regular ed.) (01-09-1997)“…A study investigates what determines the structure of the cortex, whether it is encoded by DNA or if it is a tabula rasa waiting for experiences…”
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Theory meets experiment: correlated neural activity helps determine ocular dominance column periodicity
Published in Trends in neurosciences (Regular ed.) (01-10-1995)“…The development of ocular dominance columns in primary visual cortex has attracted much interest from both experimentalists and theoreticians. One key…”
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Diffusion in Axon Guidance
Published in The European journal of neuroscience (01-07-1997)“…Axon guidance by target‐derived diffusible factors plays an important role in the development of the nervous system. This paper considers the constraints…”
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Predicting axonal response to molecular gradients with a computational model of filopodial dynamics
Published in Neural computation (01-11-2004)“…Axons are often guided to their targets in the developing nervous system by attractive or repulsive molecular concentration gradients. We propose a…”
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15
An Evaluation of the Use of Multidimensional Scaling for Understanding Brain Connectivity
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (30-05-1995)“…A large amount of data is now available about the pattern of connections between brain regions. Computational methods are increasingly relevant for uncovering…”
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A theoretical model of axon guidance by the Robo code
Published in Neural computation (01-03-2003)“…After crossing the midline, different populations of commissural axons in Drosophila target specific longitudinal pathways at different distances from the…”
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Analysis of the elastic net model applied to the formation of ocular dominance and orientation columns
Published in Network (Bristol) (01-05-2000)“…The development and structure of orientation (OR) and ocular dominance (OD) maps in the primary visual cortex of cats and monkeys can be modelled using the…”
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Dating Behavior of the Retinal Ganglion Cell
Published in Neuron (01-03-2000)Get full text
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Auto-SOM: recursive parameter estimation for guidance of self-organizing feature maps
Published in Neural computation (01-03-2001)“…An important technique for exploratory data analysis is to form a mapping from the high-dimensional data space to a low-dimensional representation space such…”
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Are visual cortex maps optimized for coverage?
Published in Neural computation (01-07-2002)“…The elegant regularity of maps of variables such as ocular dominance, orientation, and spatial frequency in primary visual cortex has prompted many people to…”
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