Search Results - "Goodhead, D. T"

Computational Approach for Determining the Spectrum of DNA Damage Induced by Ionizing Radiation by Nikjoo, H., O'Neill, P., Wilson, W. E., Goodhead, D. T.

“…Nikjoo, H., O'Neill, P., Wilson, W. E. and Goodhead, D. T. Computational Approach for Determining the Spectrum of DNA Damage Induced by Ionizing Radiation…”
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Computational modelling of low-energy electron-induced DNA damage by early physical and chemical events by NIKJOO, P. O'NEILL, D. T. GOODHEAD and M. TERRISSOL, H.

“…Modelling and calculations are presented as a first step towards mechanistic interpretation and prediction of radiation effects based on the spectrum of…”
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Initial events in the cellular effects of ionizing radiations: clustered damage in DNA by Goodhead, D T

“…General correlations are found between the detailed spatial and temporal nature of the initial physical features of radiation insult and the likelihood of…”
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BIOLOGICAL EFFECTIVENESS OF LOWER-ENERGY PHOTONS FOR CANCER RISK by Goodhead, D T

“…For risk assessment of photon exposures, the energy-dependence of relative effectiveness may be required. The NCRP has recently addressed this need by…”
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Chromosomal Instability in the Descendants of Unirradiated Surviving Cells after α -Particle Irradiation by Lorimore, S. A., Kadhim, M. A., Pocock, D. A., Papworth, D., Stevens, D. L., Goodhead, D. T., Wright, E. G.

“…We have demonstrated chromosomal instability in the clonal descendants of hemopoietic stem cells after irradiating murine bone marrow with α -particles…”
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Track structure in radiation biology: theory and applications by NIKJOO, H, UEHARA, S, WILSON, W. E, HOSHI, M, GOODHEAD, D. T

“…Purpose: A brief review is presented of the basic concepts in track structure and the relative merit of various theoretical approaches adopted in Monte-Carlo…”
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Modelling of DNA Damage Induced by Energetic Electrons (100 eV to 100 keV) by Nikjoo, H., E. Bolton, C., Watanabe, R., Terrissol, M., O'Neill, P., T. Goodhead, D.

“…Modelling and calculations are presented for the spectrum of initial DNA damage produced by 100 eV to 100 keV energetic electrons. Analysis of the initial…”
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Model for Radial Dependence of Frequency Distributions for Energy Imparted in Nanometer Volumes from HZE Particles by Cucinotta, F. A., Nikjoo, H., Goodhead, D. T.

“…Cucinotta, F. A., Nikjoo, H. and Goodhead, D. T. Model for Radial Dependence of Frequency Distributions for Energy Imparted in Nanometer Volumes from HZE…”
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Complex chromosome aberrations in peripheral blood lymphocytes as a potential biomarker of exposure to high-LET alpha-particles by ANDERSON, R. M, MARSDEN, S. J, WRIGHT, E. G, KADHIM, M. A, GOODHEAD, D. T, GRIFFIN, C. S

“…Purpose: To determine the induction and transmission, to second and third division cells, of complex chromosome aberrations in peripheral blood lymphocytes…”
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Quantitative modelling of DNA damage using Monte Carlo track structure method by Nikjoo, H, O'Neill, P, Terrissol, M, Goodhead, D T

“…This paper presents data on modelling of DNA damage induced by electrons, protons and alpha-particles to provide an insight into factors which determine the…”
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Classical approaches to microdosimetry, with example of use in radiation protection, medicine and mechanistic understanding by Goodhead, D T

“…Microdosimetry is the study and application of the microscopic features and stochastics of ionising radiations that cannot be described by the average…”
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Transmission of chromosomal instability after plutonium α-particle irradiation by Kadhim, M. A, Macdonald, D. A, Goodhead, D. T, Lorimore, S. A, Marsden, S. J, Wright, E. G

“…When investigating the biological effects of ionizing radiation on the haemopoietic system, a confounding problem lies in possible differences between the…”
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A New Standard DNA Damage (SDD) Data Format by Schuemann, J., McNamara, A. L., Warmenhoven, J. W., Henthorn, N. T., Kirkby, K. J., Merchant, M. J., Ingram, S., Paganetti, H., Held, K. D., Ramos-Mendez, J., Faddegon, B., Perl, J., Goodhead, D. T., Plante, I., Rabus, H., Nettelbeck, H., Friedland, W., Kundrát, P., Ottolenghi, A., Baiocco, G., Barbieri, S., Dingfelder, M., Incerti, S., Villagrasa, C., Bueno, M., Bernal, M. A., Guatelli, S., Sakata, D., Brown, J. M. C., Francis, Z., Kyriakou, I., Lampe, N., Ballarini, F., Carante, M. P., Davídková, M., Štěpán, V., Jia, X., Cucinotta, F. A., Schulte, R., Stewart, R. D., Carlson, D. J., Galer, S., Kuncic, Z., Lacombe, S., Milligan, J., Cho, S. H., Sawakuchi, G., Inaniwa, T., Sato, T., Li, W., Solov'yov, A. V., Surdutovich, E., Durante, M., Prise, K. M., McMahon, S. J.

“…Our understanding of radiation-induced cellular damage has greatly improved over the past few decades. Despite this progress, there are still many obstacles to…”
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Long-Term Genomic Instability in Human Lymphocytes Induced by Single-Particle Irradiation by Kadhim, M. A., Marsden, S. J., Malcolmson, A. M., Folkard, M., Goodhead, D. T., Prise, K. M., Michael, B. D.

“…Kadhim, M. A., Marsden, S. J., Malcolmson, A. M., Folkard, M., Goodhead, D. T., Prise, K. M. and Michael, B. D. Long-Term Genomic Instability in Human…”
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The Effects of Delta Rays on the Number of Particle-Track Traversals per Cell in Laboratory and Space Exposures by Cucinotta, Francis A., Nikjoo, Hooshang, Goodhead, Dudley T.

“…It is a common practice to estimate the number of particle-track traversals per cell or cell nucleus as the product of the ion's linear energy transfer (LET)…”
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Alpha-particle-induced chromosomal instability in human bone marrow cells by Kadhim, M A, Lorimore, S A, Hepburn, M D, Goodhead, D T, Buckle, V J, Wright, E G

“…alpha-particles, which are ionising radiation of high linear-energy-transfer emitted, for example, from radon or plutonium, pass through tissue as highly…”
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Kinetics of DSB rejoining and formation of simple chromosome exchange aberrations by Cucinotta, F. A., Nikjoo, H., O'Neill, P., Goodhead, D. T.

“…Purpose : To investigate the role of kinetics in the processing of DNA double strand breaks (DSB), and the formation of simple chromosome exchange aberrations…”
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Comparison and Assessment of Electron Cross Sections for Monte Carlo Track Structure Codes by Uehara, Shuzo, Nikjoo, Hooshang, Goodhead, Dudley T.

“…The purpose of this study was to make an intercomparison and assessment of cross sections for electrons in water used in electron track structure codes. This…”
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Cell Inactivation and Double-Strand Breaks: The Role of Core Ionizations, as Probed by Ultrasoft X Rays by Fayard, B., Touati, A., Abel, F., Herve du Penhoat, M. A., Despiney-Bailly, I., Gobert, F., Ricoul, M., L'Hoir, A., Politis, M. F., Hill, M. A., Stevens, D. L., Sabatier, L., Sage, E., Goodhead, D. T., Chetioui, A.

“…Fayard, B., Touati, A., Abel, F., Hervé du Penhoat, M. A., Despiney-Bailly, I., Gobert, F., Ricoul, M., L'Hoir, A., Politis, M. F., Hill, M. A., Stevens, D…”
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Radiation-induced genomic instability: delayed cytogenetic aberrations and apoptosis in primary human bone marrow cells by Kadhim, M A, Lorimore, S A, Townsend, K M, Goodhead, D T, Buckle, V J, Wright, E G

“…Transmissible chromosomal instability, characterized by non-clonal cytogenetic aberrations with a high frequency of chromatid-type aberrations together with a…”
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