Search Results - "Goodfellow, Ian G"

Norovirus gene expression and replication by Thorne, Lucy G, Goodfellow, Ian G

“…Noroviruses are small, positive-sense RNA viruses within the family Caliciviridae, and are now accepted widely as a major cause of acute gastroenteritis in…”
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Calicivirus VP2 forms a portal-like assembly following receptor engagement by Conley, Michaela J., McElwee, Marion, Azmi, Liyana, Gabrielsen, Mads, Byron, Olwyn, Goodfellow, Ian G., Bhella, David

“…To initiate infection, many viruses enter their host cells by triggering endocytosis following receptor engagement. However, the mechanisms by which…”
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Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion by Papa, Guido, Mallery, Donna L, Albecka, Anna, Welch, Lawrence G, Cattin-Ortolá, Jérôme, Luptak, Jakub, Paul, David, McMahon, Harvey T, Goodfellow, Ian G, Carter, Andrew, Munro, Sean, James, Leo C

“…Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) infects cells by binding to the host cell receptor ACE2 and undergoing virus-host membrane fusion…”
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Advances in Norovirus Biology by Karst, Stephanie M., Wobus, Christiane E., Goodfellow, Ian G., Green, Kim Y., Virgin, Herbert W.

“…Human noroviruses are a major cause of epidemic and sporadic gastroenteritis worldwide and can chronically infect immunocompromised patients. Efforts to…”
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The molecular pathology of noroviruses by Karst, Stephanie M, Zhu, Shu, Goodfellow, Ian G

“…Norovirus infection in humans typically results in acute gastroenteritis but may also occur in many animal species. Noroviruses are recognized as one of the…”
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Norovirus infection results in eIF2α independent host translation shut-off and remodels the G3BP1 interactome evading stress granule formation by Brocard, Michèle, Iadevaia, Valentina, Klein, Philipp, Hall, Belinda, Lewis, Glenys, Lu, Jia, Burke, James, Willcocks, Margaret M, Parker, Roy, Goodfellow, Ian G, Ruggieri, Alessia, Locker, Nicolas

“…Viral infections impose major stress on the host cell. In response, stress pathways can rapidly deploy defence mechanisms by shutting off the protein synthesis…”
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Leaked genomic and mitochondrial DNA contribute to the host response to noroviruses in a STING-dependent manner by Jahun, Aminu S., Sorgeloos, Frederic, Chaudhry, Yasmin, Arthur, Sabastine E., Hosmillo, Myra, Georgana, Iliana, Izuagbe, Rhys, Goodfellow, Ian G.

“…The cGAS-STING pathway is central to the interferon response against DNA viruses. However, recent studies are increasingly demonstrating its role in the…”
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Host cells reprogram lipid droplet synthesis through YY1 to resist PRRSV infection by Zheng, Zifang, Ling, Xue, Li, Yang, Qiao, Shuang, Zhang, Shuangquan, Wu, Jie, Ma, Zhiqian, Li, Mingyu, Guo, Xuyang, Li, Zhiwei, Feng, Yingtong, Liu, Xiao, Goodfellow, Ian G, Zheng, Haixue, Xiao, Shuqi

“…Metabolism in host cells can be modulated after viral infection, favoring viral survival or clearance. Here, we report that lipid droplet (LD) synthesis in…”
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The Cryo-Electron Microscopy Structure of Feline Calicivirus Bound to Junctional Adhesion Molecule A at 9-Angstrom Resolution Reveals Receptor-Induced Flexibility and Two Distinct Conformational Changes in the Capsid Protein VP1 by BHELLA, David, GOODFELLOW, Ian G

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation by Hosmillo, Myra, Lu, Jia, McAllaster, Michael R, Eaglesham, James B, Wang, Xinjie, Emmott, Edward, Domingues, Patricia, Chaudhry, Yasmin, Fitzmaurice, Tim J, Tung, Matthew Kh, Panas, Marc Dominik, McInerney, Gerald, Locker, Nicolas, Wilen, Craig B, Goodfellow, Ian G

“…Knowledge of the host factors required for norovirus replication has been hindered by the challenges associated with culturing human noroviruses. We have…”
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Porcine Sapovirus Protease Controls the Innate Immune Response and Targets TBK1 by Georgana, Iliana, Hosmillo, Myra, Jahun, Aminu S, Emmott, Edward, Sorgeloos, Frederic, Cho, Kyoung-Oh, Goodfellow, Ian G

“…Human sapoviruses (HuSaVs) and noroviruses are considered the leading cause of acute gastroenteritis worldwide. While extensive research has focused on…”
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An optimized protocol for the extraction and quantification of cytosolic DNA in mammalian cells by Jahun, Aminu S., Sorgeloos, Frederic, Goodfellow, Ian G.

“…Leakage of mitochondrial or nuclear DNA into the cytosol can occur following viral infections, radiation damage, and some cancers. Here, we present an…”
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Norovirus Translation Requires an Interaction between the C Terminus of the Genome-linked Viral Protein VPg and Eukaryotic Translation Initiation Factor 4G by Chung, Liliane, Bailey, Dalan, Leen, Eoin N., Emmott, Edward P., Chaudhry, Yasmin, Roberts, Lisa O., Curry, Stephen, Locker, Nicolas, Goodfellow, Ian G.

“…Viruses have evolved a variety of mechanisms to usurp the host cell translation machinery to enable translation of the viral genome in the presence of high…”
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Norovirus RNA Synthesis Is Modulated by an Interaction between the Viral RNA-Dependent RNA Polymerase and the Major Capsid Protein, VP1 by Subba-Reddy, Chennareddy V, Yunus, Muhammad Amir, Goodfellow, Ian G, Kao, C Cheng

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Microfluidic antibody profiling after repeated SARS-CoV-2 vaccination links antibody affinity and concentration to impaired immunity and variant escape in patients on anti-CD20 therapy by Priddey, Ashley, Chen-Xu, Michael Xin Hua, Cooper, Daniel James, MacMillan, Serena, Meisl, Georg, Xu, Catherine K, Hosmillo, Myra, Goodfellow, Ian G, Kollyfas, Rafael, Doffinger, Rainer, Bradley, John R, Mohorianu, Irina I, Jones, Rachel, Knowles, Tuomas P J, Smith, Rona, Kosmoliaptsis, Vasilis

“…Patients with autoimmune/inflammatory conditions on anti-CD20 therapies, such as rituximab, have suboptimal humoral responses to vaccination and are vulnerable…”
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A Conserved Interaction between a C-Terminal Motif in Norovirus VPg and the HEAT-1 Domain of eIF4G Is Essential for Translation Initiation by Leen, Eoin N, Sorgeloos, Frédéric, Correia, Samantha, Chaudhry, Yasmin, Cannac, Fabien, Pastore, Chiara, Xu, Yingqi, Graham, Stephen C, Matthews, Stephen J, Goodfellow, Ian G, Curry, Stephen

“…Translation initiation is a critical early step in the replication cycle of the positive-sense, single-stranded RNA genome of noroviruses, a major cause of…”
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Bioinformatic and functional analysis of RNA secondary structure elements among different genera of human and animal caliciviruses by Simmonds, Peter, Karakasiliotis, Ioannis, Bailey, Dalan, Chaudhry, Yasmin, Evans, David J, Goodfellow, Ian G

“…The mechanism and role of RNA structure elements in the replication and translation of Caliciviridae remains poorly understood. Several algorithmically…”
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Recovery of genetically defined murine norovirus in tissue culture by using a fowlpox virus expressing T7 RNA polymerase by Chaudhry, Yasmin, Skinner, Michael A, Goodfellow, Ian G

“…1 Calicivirus Research Group, Department of Virology, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London W2 1PG, UK 2…”
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Structural Insights into Calicivirus Attachment and Uncoating by BHELLA, David, GATHERER, Derek, CHAUDHRY, Yasmin, PINK, Rebecca, GOODFELLOW, Ian G

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures by Conley, Michaela, Emmott, Edward, Orton, Richard, Taylor, David, Carneiro, Daniel G, Murata, Kazuyoshi, Goodfellow, Ian G, Hansman, Grant S, Bhella, David

“…Vesivirus 2117 is an adventitious agent that, in 2009, was identified as a contaminant of Chinese hamster ovary cells propagated in bioreactors at a…”
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