Search Results - "Goodchild, Jim"
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The Drosophila nicotinic acetylcholine receptor subunits Dα5 and Dα7 form functional homomeric and heteromeric ion channels
Published in BMC neuroscience (22-06-2012)“…Nicotinic acetylcholine receptors (nAChRs) play an important role as excitatory neurotransmitters in vertebrate and invertebrate species. In insects, nAChRs…”
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The Apis mellifera alpha 5 nicotinic acetylcholine receptor subunit expresses as a homomeric receptor that is sensitive to serotonin
Published in Pesticide biochemistry and physiology (01-03-2022)“…Insect nicotinic acetylcholine receptors (nAChRs) are molecular targets of highly effective insecticides such as neonicotinoids. Functional expression of these…”
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The invertebrate pharmacology of insecticides acting at nicotinic acetylcholine receptors
Published in Journal of Pesticide Science (01-01-2017)“…The nicotinic acetylcholine receptor (nAChR) is a ligand-gated ion channel composed of 5 protein subunits arranged around a central cation selective pore…”
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4
Agonist and antagonist properties of an insect GABA-gated chloride channel (RDL) are influenced by heterologous expression conditions
Published in PloS one (07-07-2021)“…Pentameric ligand-gated ion channels (pLGICs) activated by the inhibitory neurotransmitter γ-aminobutyric acid (GABA) are expressed widely in both vertebrate…”
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Investigating the mode of action of sulfoxaflor: a fourth‐generation neonicotinoid
Published in Pest management science (01-05-2013)“…BACKGROUND: The precise mode of action of sulfoxaflor, a new nicotinic acetylcholine receptor‐modulating insecticide, is unclear. A detailed understanding of…”
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The VAChTY49N mutation provides insecticide-resistance but perturbs evoked cholinergic neurotransmission in Drosophila
Published in PloS one (2018)“…Global agriculture and the control of insect disease vectors have developed with a heavy reliance on insecticides. The increasing incidence of resistance, for…”
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The VAChT.sup.Y49N mutation provides insecticide-resistance but perturbs evoked cholinergic neurotransmission in Drosophila
Published in PloS one (11-09-2018)“…Global agriculture and the control of insect disease vectors have developed with a heavy reliance on insecticides. The increasing incidence of resistance, for…”
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8
Agonist and antagonist properties of an insect GABA-gated chloride channel
Published in PloS one (07-07-2021)“…Pentameric ligand-gated ion channels (pLGICs) activated by the inhibitory neurotransmitter [gamma]-aminobutyric acid (GABA) are expressed widely in both…”
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Identifying Ryanodine Receptor Modulators: from High-Throughput Screening to Single Channel Recording
Published in Biophysical journal (07-02-2020)Get full text
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10
Central cholinergic synaptic vesicle loading obeys the set-point model in Drosophila
Published in Journal of neurophysiology (01-02-2016)“…Experimental evidence shows that neurotransmitter release, from presynaptic terminals, can be regulated by altering transmitter load per synaptic vesicle (SV)…”
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A Poly-Glutamine Region in the Drosophila VAChT Dictates Fill-Level of Cholinergic Synaptic Vesicles
Published in eNeuro (01-01-2019)“…While the primary role of vesicular transporters is to load neurotransmitters into synaptic vesicles (SVs), accumulating evidence suggests that these proteins…”
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ニコチン性アセチルコリン受容体に作用する殺虫剤の無脊椎動物における薬理学
Published in Journal of Pesticide Science (20-08-2017)Get full text
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The Drosophila nicotinic acetylcholine receptor subunits D[alpha]5 and D[alpha]7 form functional homomeric and heteromeric ion channels
Published in BMC neuroscience (22-06-2012)“…Background Nicotinic acetylcholine receptors (nAChRs) play an important role as excitatory neurotransmitters in vertebrate and invertebrate species. In…”
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14
Speech privacy in closed offices: Comparison of languages and accent
Published in The Journal of the Acoustical Society of America (01-11-2001)“…Up to now, most objective assessments for speech privacy and speech intelligibility, such as articulation index (AI), speech intelligibility index (SII),…”
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A study on speech privacy in closed offices
Published in The Journal of the Acoustical Society of America (01-05-2001)“…Quantification of speech privacy in closed spaces is dependent on several factors: attenuation and absorption characteristics of the construction, background…”
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Assessment of language impact to speech privacy in closed offices
Published in The Journal of the Acoustical Society of America (01-11-2002)“…Speech privacy is the opposite concept of speech intelligibility and can be assessed by the predictors of speech intelligibility. Based on the existing…”
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