Search Results - "Goodall, J"

A network-biology perspective of microRNA function and dysfunction in cancer by Bracken, Cameron P., Scott, Hamish S., Goodall, Gregory J.

“…Key Points MicroRNAs (miRNAs) have important functions in controlling many cell properties, including cell growth and differentiation. Their dysregulation is a…”
Get full text

Ethical Decision Making during Automated Vehicle Crashes by Goodall, Noah J.

“…Automated vehicles have received much attention recently, particularly the Defense Advanced Research Projects Agency Urban Challenge vehicles, Google's…”
Get full text

Away from Trolley Problems and Toward Risk Management by Goodall, Noah J.

“…As automated vehicles receive more attention from the media, there has been an equivalent increase in the coverage of the ethical choices a vehicle may be…”
Get full text

IsomiRs – the overlooked repertoire in the dynamic microRNAome by Neilsen, Corine T, Goodall, Gregory J, Bracken, Cameron P

“…The development of deep sequencing has enabled the identification of novel microRNAs (miRNAs), leading to a growing appreciation for the fact that individual…”
Get full text

Soluble heparan sulfate fragments generated by heparanase trigger the release of pro-inflammatory cytokines through TLR-4 by Goodall, Katharine J, Poon, Ivan K H, Phipps, Simon, Hulett, Mark D

“…Heparanase is a β-D-endoglucuronidase that cleaves heparan sulfate (HS), facilitating degradation of the extracellular matrix (ECM) and the release of HS-bound…”
Get full text

Bio-inspired CO2 conversion by iron sulfide catalysts under sustainable conditions by Roldan, A, Hollingsworth, N, Roffey, A, Islam, H-U, Goodall, J B M, Catlow, C R A, Darr, J A, Bras, W, Sankar, G, Holt, K B, Hogarth, G, de Leeuw, N H

“…The mineral greigite presents similar surface structures to the active sites found in many modern-day enzymes. We show that particles of greigite can reduce…”
Get more information

The RNA Binding Protein Quaking Regulates Formation of circRNAs by Conn, Simon J., Pillman, Katherine A., Toubia, John, Conn, Vanessa M., Salmanidis, Marika, Phillips, Caroline A., Roslan, Suraya, Schreiber, Andreas W., Gregory, Philip A., Goodall, Gregory J.

“…Circular RNAs (circRNAs), formed by non-sequential back-splicing of pre-mRNA transcripts, are a widespread form of non-coding RNA in animal cells. However, it…”
Get full text

The many regulators of epithelial−mesenchymal transition by Bracken, Cameron P., Goodall, Gregory J.

“…Epithelial−mesenchymal transition (EMT) is a complex, highly regulated process that is reportedly controlled by hundreds of transcription factors and hundreds…”
Get full text

A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure by Atkin-Smith, Georgia K., Tixeira, Rochelle, Paone, Stephanie, Mathivanan, Suresh, Collins, Christine, Liem, Michael, Goodall, Katharine J., Ravichandran, Kodi S., Hulett, Mark D., Poon, Ivan K.H.

“…Disassembly of apoptotic cells into smaller fragments (a form of extracellular vesicle called apoptotic bodies) can facilitate removal of apoptotic debris and…”
Get full text

Chemotherapy versus surgery for initial treatment in advanced ovarian epithelial cancer by Coleridge, Sarah L, Bryant, Andrew, Lyons, Thomas J, Goodall, Richard J, Kehoe, Sean, Morrison, Jo

“…Epithelial ovarian cancer presents at an advanced stage in the majority of women. These women require surgery and chemotherapy for optimal treatment…”
Get more information

On measuring miRNAs after transient transfection of mimics or antisense inhibitors by Thomson, Daniel W, Bracken, Cameron P, Szubert, Jan M, Goodall, Gregory J

“…The ability to alter microRNA (miRNA) abundance is crucial for studying miRNA function. To achieve this there is widespread use of both exogenous…”
Get full text

Technology and school-home communication by Goodall, J. S.

“…This paper examines the linked concepts of school-home communications, and parental engagement in children's learning, both of which are vital for supporting…”
Get full text

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition by BRACKEN, Cameron P, GREGORY, Philip A, KOLESNIKOFF, Natasha, BERT, Andrew G, JUN WANG, SHANNON, M. Frances, GOODALL, Gregory J

“…Epithelial to mesenchymal transition occurs during embryologic development to allow tissue remodeling and is proposed to be a key step in the metastasis of…”
Get full text

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 by Vadas, Mathew A, Paterson, Emily L, Farshid, Gelareh, Khew-Goodall, Yeesim, Bert, Andrew G, Barry, Simon C, Tsykin, Anna, Goodall, Gregory J, Gregory, Philip A

“…Epithelial to mesenchymal transition (EMT) facilitates tissue remodelling during embryonic development and is viewed as an essential early step in tumour…”
Get full text

Down-Regulation of the miRNA-200 Family at the Invasive Front of Colorectal Cancers with Degraded Basement Membrane Indicates EMT Is Involved in Cancer Progression by Paterson, Emily L, Kazenwadel, Jan, Bert, Andrew G, Khew-Goodall, Yeesim, Ruszkiewicz, Andrew, Goodall, Gregory J

“…Abstract Cancer progression is a complex series of events thought to incorporate the reversible developmental process of epithelial-to-mesenchymal transition…”
Get full text

MicroRNAs as regulators of epithelial-mesenchymal transition by Gregory, Philip A., Bracken, Cameron P., Bert, Andrew G., Goodall, Gregory J.

“…Epithelial-mesenchymal transition (EMT) describes the molecular reprogramming and phenotypic changes involved in the conversion of polarised immotile…”
Get full text

Network-Based Approaches to Understand the Roles of miR-200 and Other microRNAs in Cancer by Bracken, Cameron P, Khew-Goodall, Yeesim, Goodall, Gregory J

“…microRNAs (miRNA) are well suited to the task of regulating gene expression networks, because any given miRNA has the capacity to target dozens, if not…”
Get full text

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression by Gibbons, Don L, Lin, Wei, Creighton, Chad J, Rizvi, Zain H, Gregory, Philip A, Goodall, Gregory J, Thilaganathan, Nishan, Du, Liqin, Zhang, Yiqun, Pertsemlidis, Alexander, Kurie, Jonathan M

“…Metastatic disease is a primary cause of cancer-related death, and factors governing tumor cell metastasis have not been fully elucidated. Here, we address…”
Get full text

Herbicide trials on Campuloclinium macrocephalum (Asteraceae) during adverse conditions reveal incompatibility with biocontrol and a narrow window of opportunity for chemical control by Goodall, JM, Witkowski, ETF

“…Herbicide trials on pompom weed Campuloclinium macrocephalum (Less.) DC. (Asteraceae) were carried out in grasslands with xeric and hydric soils, at sites in…”
Get full text

Circulating microRNAs predict biochemical recurrence in prostate cancer patients by Selth, L A, Townley, S L, Bert, A G, Stricker, P D, Sutherland, P D, Horvath, L G, Goodall, G J, Butler, L M, Tilley, W D

“…Background: Circulating microRNAs (miRNAs) are emerging as promising biomarkers for prostate cancer. Here, we investigated the potential of these molecules to…”
Get full text