Search Results - "Goodall, AH"

White Cell Telomere Length and Risk of Premature Myocardial Infarction by Brouilette, Scott, Singh, Ravi K, Thompson, John R, Goodall, Alison H, Samani, Nilesh J

“…OBJECTIVE—Biological age may be distinct from chronological age and contribute to the pathogenesis of age-related diseases. Mean telomeres lengths provide an…”
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Dimorphism in the P2Y1 ADP Receptor Gene Is Associated With Increased Platelet Activation Response to ADP by Hetherington, Simon L, Singh, Ravi K, Lodwick, David, Thompson, John R, Goodall, Alison H, Samani, Nilesh J

“…OBJECTIVE—The platelet ADP receptors P2Y1 and P2Y12 play a pivotal role in platelet aggregation. There is marked interindividual variation in platelet response…”
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Large-scale association analysis identifies new risk loci for coronary artery disease by Willenborg, Christina, Farrall, Martin, Assimes, Themistocles L, Thompson, John R, Ingelsson, Erik, Goldstein, Benjamin A, Stirrups, Kathleen, König, Inke R, Cazier, Jean-Baptiste, Lee, Jong-Young, Chambers, John C, Esko, Tõnu, Folkersen, Lasse, Havulinna, Aki S, Ho, Weang K, Hopewell, Jemma C, Shungin, Dmitry, Van Zuydam, Natalie, Voight, Benjamin F, Zhang, Weihua, Ziegler, Andreas, Altshuler, David, Balmforth, Anthony J, Dimitriou, Maria, Mokhtari, NourEddine El, Fischer, Krista, Fontanillas, Pierre, Franco-Cereceda, Anders, Groop, Leif, Hager, Jörg, Hallmans, Göran, Han, Bok-Ghee, Hunt, Sarah E, Kessler, Thorsten, Kuusisto, Johanna, Lokki, Marja-Liisa, Lundmark, Anders, McCarthy, Mark I, Meisinger, Christa, Melander, Olle, Mihailov, Evelin, Nikus, Kjell, Peden, John F, Rasheed, Asif, Rubin, Diana, Thorgeirsson, Gudmundur, Wells, George A, Wild, Philipp S, Yang, Tsun-Po, Amouyel, Philippe, Basart, Hanneke, Boehnke, Michael, Boerwinkle, Eric, Brambilla, Paolo, Cupples, Adrienne L, de Faire, Ulf, Epstein, Stephen E, Ferrario, Marco M, Ferrières, Jean, Go, Alan S, Gudnason, Villi, Hazen, Stanley L, Jang, Yangsoo, Kim, Hyo-Soo, Kratzer, Wolfgang, Kuulasmaa, Kari, Laaksonen, Reijo, Lee, Ji-Young, Park, Jeong E, Peters, Annette, Quertermous, Thomas, Salomaa, Veikko, Schadt, Eric, Shah, Svati H, Sinisalo, Juha, Stark, Klaus, Stefansson, Kari, Wallentin, Lars, Wareham, Nicholas, Hengstenberg, Christian, Sandhu, Manjinder S, Pastinen, Tomi, Syvänen, Ann-Christine, Hovingh, G Kees, Franks, Paul W, Lehtimäki, Terho, Siegbahn, Agneta, Schreiber, Stefan, Blankenberg, Stefan S, Perola, Markus, Clarke, Robert, O'Donnell, Christopher, Reilly, Muredach P, März, Winfried, Collins, Rory, Thorsteinsdottir, Unnur, Danesh, John, Palmer, Colin N A, Schunkert, Heribert, Samani, Nilesh J

“…Panos Deloukas, Nilesh Samani and colleagues report a large-scale association analysis using the Metabochip array in 63,746 coronary artery disease cases and…”
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Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease by Schunkert, Heribert, Kathiresan, Sekar, Stewart, Alexandre F R, Barbalic, Maja, Absher, Devin, Aherrahrou, Zouhair, Allayee, Hooman, Anand, Sonia S, Anderson, Jeffrey L, Ardissino, Diego, Balmforth, Anthony J, Boerwinkle, Eric, Braund, Peter S, Brown, Morris J, Burnett, Mary Susan, Buysschaert, Ian, Carlquist, John F, Chen, Li, Cichon, Sven, Davies, Robert W, Dehghan, Abbas, Demissie, Serkalem, Do, Ron, Eifert, Sandra, Mokhtari, Nour Eddine El, Elosua, Roberto, Engert, James C, Epstein, Stephen E, Fischer, Marcus, Folsom, Aaron R, Freyer, Jennifer, Halperin, Eran, Hammond, Naomi, Hazen, Stanley L, Horne, Benjamin D, Illig, Thomas, Iribarren, Carlos, Kaiser, Michael A, Kaplan, Lee M, Kastelein, John J P, Laaksonen, Reijo, Leander, Karin, Lettre, Guillaume, Li, Mingyao, Loley, Christina, Lotery, Andrew J, Mannucci, Pier M, Maouche, Seraya, Martinelli, Nicola, Meisinger, Christa, Melander, Olle, Mooser, Vincent, Mühleisen, Thomas W, Münzel, Thomas, Musunuru, Kiran, Nelson, Christopher P, Nöthen, Markus M, Olivieri, Oliviero, Patel, Riyaz S, Patterson, Chris C, Peters, Annette, Peyvandi, Flora, Quyyumi, Arshed A, Rallidis, Loukianos S, Rice, Catherine, Rosendaal, Frits R, Salomaa, Veikko, Sampietro, M Lourdes, Schäfer, Arne, Schillert, Arne, Schreiber, Stefan, Schrezenmeir, Jürgen, Schwartz, Stephen M, Sivananthan, Mohan, Smith, Albert, Smith, Tamara B, Snoep, Jaapjan D, Soranzo, Nicole, Spertus, John A, Stark, Klaus, Stirrups, Kathy, Stoll, Monika, Tang, W H Wilson, Thorgeirsson, Gudmundur, Thorleifsson, Gudmar, van Rij, Andre M, Wells, George A, Wichmann, H-Erich, Wild, Philipp S, Willenborg, Christina, Zeller, Tanja, Ziegler, Andreas, Cambien, Francois, Hengstenberg, Christian, Blankenberg, Stefan, Ouwehand, Willem H, Hall, Alistair S, Thompson, John R, McPherson, Ruth, Erdmann, Jeanette

“…Heribert Schunkert and colleagues report a meta-analysis of 14 genome-wide association studies of coronary disease (CAD) followed by replication in additional…”
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Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies by Sarwar, Nadeem, Butterworth, Adam S, Freitag, Daniel F, Gregson, John, Willeit, Peter, Gorman, Donal N, Gao, Pei, Saleheen, Danish, Rendon, Augusto, Nelson, Christopher P, Braund, Peter S, Hall, Alistair S, Chasman, Daniel I, Tybjærg-Hansen, Anne, Chambers, John C, Benjamin, Emelia J, Franks, Paul W, Clarke, Robert, Wilde, Arthur A M, Trip, Mieke D, Steri, Maristella, Witteman, Jacqueline C M, Qi, Lu, van der Schoot, C Ellen, de Faire, Ulf, Erdmann, Jeanette, Stringham, Heather M, Koenig, Wolfgang, Rader, Daniel J, Melzer, David, Reich, David, Psaty, Bruce M, Kleber, Marcus E, Panagiotakos, Demosthenes B, Willeit, Johann, Wennberg, Patrik, Woodward, Mark, Adamovic, Svetlana, Rimm, Eric B, Meade, Tom W, Gillum, Richard F, Shaffer, Jonathan A, Hofman, Albert, Onat, Altan, Sundström, Johan, Wassertheil-Smoller, Sylvia, Mellström, Dan, Gallacher, John, Cushman, Mary, Tracy, Russell P, Kauhanen, Jussi, Karlsson, Magnus, Salonen, Jukka T, Wilhelmsen, Lars, Amouyel, Philippe, Cantin, Bernard, Best, Lyle G, Ben-Shlomo, Yoav, Manson, JoAnn E, Davey-Smith, George, de Bakker, Paul I W, O'Donnell, Christopher J, Wilson, James F, Wilson, Anthony G, Assimes, Themistocles L, Jansson, John-Olov, Ohlsson, Claes, Tivesten, Åsa, Ljunggren, Östen, Reilly, Muredach P, Hamsten, Anders, Ingelsson, Erik, Cambien, Francois, Hung, Joseph, Thomas, G Neil, Boehnke, Michael, Schunkert, Heribert, Asselbergs, Folkert W, Kastelein, John J P, Gudnason, Vilmundur, Salomaa, Veikko, Harris, Tamara B, Kooner, Jaspal S, Allin, Kristine H, Nordestgaard, Børge G, Hopewell, Jemma C, Goodall, Alison H, Ridker, Paul M, Hólm, Hilma, Watkins, Hugh, Ouwehand, Willem H, Samani, Nilesh J, Kaptoge, Stephen, Di Angelantonio, Emanuele, Harari, Olivier, Danesh, John

“…Summary Background Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6…”
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Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci by Tromp, Gerard, Gretarsdottir, Solveig, Baas, Annette F, Giusti, Betti, Strauss, Ewa, van‘t Hof, Femke N.G, Webb, Thomas R, Erdman, Robert, Ritchie, Marylyn D, Elmore, James R, Verma, Anurag, Pendergrass, Sarah, Kullo, Iftikhar J, Peissig, Peggy L, Verma, Shefali S, Malinowski, Jennifer, Rasmussen-Torvik, Laura J, Borthwick, Kenneth M, Smelser, Diane T, Crosslin, David R, de Andrade, Mariza, Ryer, Evan J, McCarty, Catherine A, Böttinger, Erwin P, Pacheco, Jennifer A, Carrell, David S, Franklin, David P, Phillips, Victoria L, Williams, Michael J.A, Wei, Wenhua, Blair, Ross, Hill, Andrew A, Vasudevan, Thodor M, Lewis, David R, Thomson, Ian A, Krysa, Jo, Hill, Geraldine B, Roake, Justin, Merriman, Tony R, Oszkinis, Grzegorz, Galora, Silvia, Saracini, Claudia, Abbate, Rosanna, Pulli, Raffaele, Saratzis, Athanasios, Verissimo, Ana R, Bumpstead, Suzannah, Badger, Stephen A, Clough, Rachel E, Cockerill, Gillian, Hafez, Hany, Scott, D. Julian A, Futers, T Simon, Romaine, Simon P.R, Griffin, Kathryn J, Bailey, Marc A, Smith, Alberto, van Bockxmeer, Frank M, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Blankensteijn, Jan D, Teijink, Joep A.W, de Graaf, Jacqueline, Kiemeney, Lambertus A, Lindholt, Jes S, Hughes, Anne, Bradley, Declan T, Stirrups, Kathleen, Golledge, Jonathan, Norman, Paul E, Powell, Janet T, Humphries, Steve E, Goodall, Alison H, Nelson, Christopher P, Sakalihasan, Natzi, Courtois, Audrey, Ferrell, Robert E, Eriksson, Per, Folkersen, Lasse, Franco-Cereceda, Anders, Eicher, John D, Johnson, Andrew D, Betsholtz, Christer, Ruusalepp, Arno, Franzén, Oscar, Schadt, Eric E, Lipovich, Leonard, Verhoeven, Eric L, Zeebregts, Clark J, Geelkerken, Robert H, van Sambeek, Marc R, van Sterkenburg, Steven M, de Vries, Jean-Paul, Stefansson, Kari, de Bakker, Paul I.W, Deloukas, Panos, Harrison, Seamus C, van Rij, Andre M, Samani, Nilesh J, Bown, Matthew J

“…RATIONALE:Abdominal aortic aneurysm (AAA) is a complex disease with both genetic and environmental risk factors. Together, 6 previously identified risk loci…”
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Meta-analysis of 65,734 Individuals Identifies TSPAN15 and SLC44A2 as Two Susceptibility Loci for Venous Thromboembolism by Germain, Marine, Chasman, Daniel I., de Haan, Hugoline, Tang, Weihong, Lindström, Sara, Weng, Lu-Chen, de Andrade, Mariza, de Visser, Marieke C.H., Wiggins, Kerri L., Suchon, Pierre, Saut, Noémie, Smadja, David M., Le Gal, Grégoire, van Hylckama Vlieg, Astrid, Di Narzo, Antonio, Hao, Ke, Nelson, Christopher P., Rocanin-Arjo, Ares, Folkersen, Lasse, Monajemi, Ramin, Rose, Lynda M., Brody, Jennifer A., Slagboom, Eline, Aïssi, Dylan, Gagnon, France, Deleuze, Jean-Francois, Deloukas, Panos, Tzourio, Christophe, Dartigues, Jean-Francois, Berr, Claudine, Taylor, Kent D., Civelek, Mete, Eriksson, Per, Psaty, Bruce M., Houwing-Duitermaat, Jeanine, Goodall, Alison H., Cambien, François, Kraft, Peter, Amouyel, Philippe, Samani, Nilesh J., Basu, Saonli, Ridker, Paul M., Rosendaal, Frits R., Kabrhel, Christopher, Folsom, Aaron R., Heit, John, Reitsma, Pieter H., Trégouët, David-Alexandre, Smith, Nicholas L., Morange, Pierre-Emmanuel

“…Venous thromboembolism (VTE), the third leading cause of cardiovascular mortality, is a complex thrombotic disorder with environmental and genetic…”
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A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy by VILLARD, Eric, PERRET, Claire, DUBOURG, Olivier, TAVAZZI, Luigi, AUMONT, Marie-Claude, DEGROOTE, Pascal, FAUCHIER, Laurent, TROCHU, Jean-Noël, GIBELIN, Pierre, AUPETIT, Jean-François, STARK, Klaus, ERDMANN, Jeanette, GARY, Françoise, HETZER, Roland, ROBERT, Angharad M, BARTON, Paul J. R, REGITZ-ZAGROSEK, Vera, ASLAM, Uzma, DUBOSCQ-BIDOT, Laëtitia, MEYBORG, Matthias, MAISCH, Bernhard, MADEIRA, Hugo, WALDENSTRÖM, Anders, PROUST, Carole, GALVE, Enrique, CLELAND, John G, DORENT, Richard, ROIZES, Gerard, ZELLER, Tanja, BLANKENBERG, Stefan, GOODALL, Alison H, COOK, Stuart, TREGOUET, David A, TIRET, Laurence, DITANIAN, Gilles, ISNARD, Richard, KOMAJDA, Michel, CHARRON, Philippe, CAMBIEN, François, HENGSTENBERG, Christian, RUPPERT, Volker, ARBUSTINI, Eloisa, WICHTER, Thomas, GERMAIN, Marine

“…Dilated cardiomyopathy (DCM) is a major cause of heart failure with a high familial recurrence risk. So far, the genetics of DCM remains largely unresolved. We…”
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Large-scale gene-centric analysis identifies novel variants for coronary artery disease by Butterworth, AS, Farrall, M, Hardwick, RJ, Saleheen, D, Peden, JF, Soranzo, N, Chambers, JC, Sivapalaratnam, S, Kleber, ME, Klopp, N, Erdmann, J, Assimes, TL, Ball, SG, Balmforth, AJ, Barnes, TA, Basart, H, Baumert, J, Bezzina, CR, Boerwinkle, E, Boehm, BO, Brocheton, J, Bugert, P, Cambien, F, Clarke, R, Codd, V, Collins, R, Couper, D, Cupples, LA, de Jong, JS, Diemert, P, Ejebe, K, Elbers, CC, Elliott, P, Fornage, M, Franzosi, MG, Frossard, P, Garner, S, Goel, A, Goodall, AH, Hengstenberg, C, Hunt, SE, Kastelein, JJP, Klungel, OH, Kluter, H, Koch, K, Konig, IR, Kooner, AS, Laaksonen, R, Lathrop, M, Li, MY, Liu, K, McPherson, R, Musameh, MD, Musani, S, Nelson, CP, O'Donnell, CJ, Ongen, H, Papanicolaou, G, Peters, A, Peters, BJM, Potter, S, Psaty, BM, Qu, LM, Rader, DJ, Rasheed, A, Rice, C, Scott, J, Seedorf, U, Sehmi, JS, Sotoodehnia, N, Stark, K, Stephens, J, van der Schoot, CE, van der Schouw, YT, Tomaszewski, M, van der Harst, P, Vasan, RS, Wilde, AAM, Willenborg, C, Winkelmann, BR, Zaidi, M, Zhang, WH, Ziegler, A, de Bakker, PIW, Koenig, W, Marz, W, Trip, MD, Reilly, MP, Kathiresan, S, Schunkert, H, Hamsten, A, Hall, AS, Kooner, JS, Thompson, SG, Thompson, JR, Deloukas, P, Ouwehand, WH, Watkins, H, Danesh, J, Samani, NJ

“…Coronary artery disease (CAD) has a significant genetic contribution that is incompletely characterized. To complement genome-wide association (GWA) studies,…”
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Blood Pressure Loci Identified with a Gene-Centric Array by Johnson, Toby, Gaunt, Tom R., Newhouse, Stephen J., Padmanabhan, Sandosh, Tomaszewski, Maciej, Kumari, Meena, Morris, Richard W., Tzoulaki, Ioanna, O'Brien, Eoin T., Poulter, Neil R., Sever, Peter, Shields, Denis C., Thom, Simon, Whincup, Peter H., Brown, Morris J., Connell, John M., Dobson, Richard J., Howard, Philip J., Mein, Charles A., Onipinla, Abiodun, Shaw-Hawkins, Sue, Zhang, Yun, Smith, George Davey, Day, Ian N.M., Lawlor, Debbie A., Goodall, Alison H., Fowkes, F. Gerald, Abecasis, Gonçalo R., Elliott, Paul, Gateva, Vesela, Braund, Peter S., Burton, Paul R., Nelson, Christopher P., Tobin, Martin D., van der Harst, Pim, Neuvrith, Hani, Salvi, Erika, Staessen, Jan A., Stucchi, Andrea, Devos, Nabila, Jeunemaitre, Xavier, Plouin, Pierre-François, Tichet, Jean, Juhanson, Peeter, Org, Elin, Putku, Margus, Sõber, Siim, Veldre, Gudrun, Viigimaa, Margus, Levinsson, Anna, Rosengren, Annika, Thelle, Dag S., Hastie, Claire E., Hedner, Thomas, Lee, Wai K., Melander, Olle, Wahlstrand, Björn, Hardy, Rebecca, Wong, Andrew, Cooper, Jackie A., Palmen, Jutta, Chen, Li, Stewart, Alexandre F.R., Wells, George A., Westra, Harm-Jan, Wolfs, Marcel G.M., Clarke, Robert, Franzosi, Maria Grazia, Goel, Anuj, Hamsten, Anders, Lathrop, Mark, Peden, John F., Seedorf, Udo, Watkins, Hugh, Sambrook, Jennifer, Stephens, Jonathan, Casas, Juan-Pablo, Drenos, Fotios, Holmes, Michael V., Kivimaki, Mika, Shah, Sonia, Shah, Tina, Talmud, Philippa J., Whittaker, John, Wallace, Chris, Delles, Christian, Laan, Maris, Kuh, Diana, Humphries, Steve E., Nyberg, Fredrik, Cusi, Daniele, Roberts, Robert, Newton-Cheh, Christopher, Franke, Lude, Stanton, Alice V., Dominiczak, Anna F., Hingorani, Aroon D., Samani, Nilesh J., Caulfield, Mark J., Munroe, Patricia B.

“…Raised blood pressure (BP) is a major risk factor for cardiovascular disease. Previous studies have identified 47 distinct genetic variants robustly associated…”
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Socrates in the Boardroom: Why Research Universities Should Be Led by Top Scholars by Goodall, Amanda H

“…"Socrates in the Boardroom" argues that world-class scholars, not administrators, make the best leaders of research universities. Amanda Goodall cuts through…”
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Telomere shortening in atherosclerosis by Samani, Nilesh J, Boultby, Rachel, Butler, Robert, Thompson, John R, Goodall, Alison H

“…Eukaryotic chromosomes end with telomeres, which shorten with cellular ageing. We investigated whether atherosclerosis is associated with systemic evidence of…”
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Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation by Huang, Jie, Sabater-Lleal, Maria, Asselbergs, Folkert W., Tregouet, David, Shin, So-Youn, Ding, Jingzhong, Baumert, Jens, Oudot-Mellakh, Tiphaine, Folkersen, Lasse, Johnson, Andrew D., Smith, Nicholas L., Williams, Scott M., Ikram, Mohammad A., Kleber, Marcus E., Becker, Diane M., Truong, Vinh, Mychaleckyj, Josyf C., Tang, Weihong, Yang, Qiong, Sennblad, Bengt, Moore, Jason H., Williams, Frances M.K., Dehghan, Abbas, Silbernagel, Günther, Schrijvers, Elisabeth M.C., Smith, Shelly, Karakas, Mahir, Tofler, Geoffrey H., Silveira, Angela, Navis, Gerjan J., Lohman, Kurt, Chen, Ming-Huei, Peters, Annette, Goel, Anuj, Hopewell, Jemma C., Chambers, John C., Saleheen, Danish, Lundmark, Per, Psaty, Bruce M., Strawbridge, Rona J., Boehm, Bernhard O., Carter, Angela M., Meisinger, Christa, Peden, John F., Bis, Joshua C., McKnight, Barbara, Öhrvik, John, Taylor, Kent, Franzosi, Maria Grazia, Seedorf, Udo, Collins, Rory, Franco-Cereceda, Anders, Syvänen, Ann-Christine, Goodall, Alison H., Yanek, Lisa R., Cushman, Mary, Müller-Nurasyid, Martina, Folsom, Aaron R., Basu, Saonli, Matijevic, Nena, van Gilst, Wiek H., Kooner, Jaspal S., Hofman, Albert, Danesh, John, Clarke, Robert, Meigs, James B., Kathiresan, Sekar, Reilly, Muredach P., Klopp, Norman, Harris, Tamara B., Winkelmann, Bernhard R., Grant, Peter J., Hillege, Hans L., Watkins, Hugh, Spector, Timothy D., Becker, Lewis C., Tracy, Russell P., März, Winfried, Uitterlinden, Andre G., Eriksson, Per, Cambien, Francois, Morange, Pierre-Emmanuel, Koenig, Wolfgang, Soranzo, Nicole, van der Harst, Pim, Liu, Yongmei, O'Donnell, Christopher J., Hamsten, Anders

“…We conducted a genome-wide association study to identify novel associations between genetic variants and circulating plasminogen activator inhibitor-1 (PAI-1)…”
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Platelet responses to agonists in a cohort of highly characterised platelet donors are consistent over time by Garner, S. F., Furnell, A., Kahan, B. C., Jones, C. I., Attwood, A., Harrison, P., Kelly, A. M., Goodall, A. H., Cardigan, R., Ouwehand, W. H.

“…Background and Objectives Platelet function shows significant inheritance that is at least partially genetically controlled. There is also evidence that the…”
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Beneficial effects of clopidogrel combined with aspirin in reducing cerebral emboli in patients undergoing carotid endarterectomy by PAYNE, David A, JONES, Chris I, HAYES, Paul D, THOMPSON, Matthew M, LONDON, Nicholas J, BELL, Peter R, GOODALL, Alison H, NAYLOR, A. Ross

“…Postoperative thromboembolic stroke affects 2% to 3% of patients undergoing carotid endarterectomy (CEA) and is preceded by 1 to 2 hours of increasing cerebral…”
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Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2 by Huang, Jie, Huffman, Jennifer E, Yamkauchi, Munekazu, Trompet, Stella, Asselbergs, Folkert W, Sabater-Lleal, Maria, Trégouët, David-Alexandre, Chen, Wei-Min, Smith, Nicholas L, Kleber, Marcus E, Shin, So-Youn, Becker, Diane M, Tang, Weihong, Dehghan, Abbas, Johnson, Andrew D, Truong, Vinh, Folkersen, Lasse, Yang, Qiong, Oudot-Mellkah, Tiphaine, Buckley, Brendan M, Moore, Jason H, Williams, Frances M.K, Campbell, Harry, Silbernagel, Günther, Vitart, Veronique, Rudan, Igor, Tofler, Geoffrey H, Navis, Gerjan J, DeStefano, Anita, Wright, Alan F, Chen, Ming-Huei, de Craen, Anton J.M, Worrall, Bradford B, Rudnicka, Alicja R, Rumley, Ann, Bookman, Ebony B, Psaty, Bruce M, Chen, Fang, Keene, Keith L, Franco, Oscar H, Böhm, Bernhard O, Uitterlinden, Andre G, Carter, Angela M, Jukema, J Wouter, Sattar, Naveed, Bis, Joshua C, Ikram, Mohammad A, Sale, Michèle M, McKnight, Barbara, Fornage, Myriam, Ford, Ian, Taylor, Kent, Slagboom, P Eline, McArdle, Wendy L, Hsu, Fang-Chi, Franco-Cereceda, Anders, Goodall, Alison H, Yanek, Lisa R, Furie, Karen L, Cushman, Mary, Hofman, Albert, Witteman, Jacqueline C.M, Folsom, Aaron R, Basu, Saonli, Matijevic, Nena, van Gilst, Wiek H, Wilson, James F, Westendorp, Rudi G.J, Kathiresan, Sekar, Reilly, Muredach P, Tracy, Russell P, Polasek, Ozren, Winkelmann, Bernhard R, Grant, Peter J, Hillege, Hans L, Cambien, Francois, Stott, David J, Lowe, Gordon D, Spector, Timothy D, Meigs, James B, Marz, Winfried, Eriksson, Per, Becker, Lewis C, Morange, Pierre-Emmanuel, Soranzo, Nicole, Williams, Scott M, Hayward, Caroline, van der Harst, Pim, Hamsten, Anders, Lowenstein, Charles J, Strachan, David P, O’Donnell, Christopher J

“…OBJECTIVE—Tissue plasminogen activator (tPA), a serine protease, catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for…”
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Identification of secreted phosphoprotein 1 gene as a new rheumatoid arthritis susceptibility gene by Gazal, Steven, Sacre, Karim, Allanore, Yannick, Teruel, Maria, Goodall, Alison H, Tohma, Shigeto, Alfredsson, Lars, Okada, Yukinori, Xie, Gang, Constantin, Arnaud, Balsa, Alejandro, Kawasaki, Aya, Nicaise, Pascale, Amos, Christopher, Rodriguez-Rodriguez, Luis, Chiocchia, Gilles, Boileau, Catherine, Zhang, Jinyi, Vittecoq, Olivier, Barnetche, Thomas, Gonzalez Gay, Miguel A, Furukawa, Hiroshi, Cantagrel, Alain, Le Loët, Xavier, Sumida, Takayuki, Hurtado-Nedelec, Margarita, Richez, Christophe, Chollet-Martin, Sylvie, Schaeverbeke, Thierry, Combe, Bernard, Khoryati, Liliane, Coustet, Baptiste, El-Benna, Jammel, Siminovitch, Katherine, Plenge, Robert, Padyukov, Leonid, Martin, Javier, Tsuchiya, Naoyuki, Dieudé, Philippe

“…To evaluate the contribution of the SPP1 rs11439060 and rs9138 polymorphisms, previously reported as autoimmune risk variants, in the rheumatoid arthritis (RA)…”
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Effect of Hypobaric Hypoxia, Simulating Conditions During Long-Haul Air Travel, on Coagulation, Fibrinolysis, Platelet Function, and Endothelial Activation by Toff, William D, Jones, Chris I, Ford, Isobel, Pearse, Robert J, Watson, Henry G, Watt, Stephen J, Ross, John A. S, Gradwell, David P, Batchelor, Anthony J, Abrams, Keith R, Meijers, Joost C. M, Goodall, Alison H, Greaves, Michael

“…CONTEXT The link between long-haul air travel and venous thromboembolism is the subject of continuing debate. It remains unclear whether the reduced cabin…”
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Galectin-1 interacts with β-1 subunit of integrin by Moiseeva, Elena P, Williams, Bryan, Goodall, Alison H, Samani, Nilesh J

“…Galectin-1, a β-galactoside-binding dimeric lectin, is involved in adhesion, migration, and proliferation of vascular smooth muscle cells (SMC), the key steps…”
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Platelet-Leukocyte Cross Talk in Whole Blood by Li, Nailin, Hu, Hu, Lindqvist, Malin, Wikström-Jonsson, Eva, Goodall, Alison H, Hjemdahl, Paul

“…Abstract—Thrombosis and inflammation involve complex platelet-leukocyte interaction, the details of which are not fully elucidated. Therefore, we investigated…”
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