Search Results - "Good, Wilson W."
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Tipping the scales of understanding: An engineering approach to design and implement whole-body cardiac electrophysiology experimental models
Published in Frontiers in physiology (19-01-2023)“…The study of cardiac electrophysiology is built on experimental models that span all scales, from ion channels to whole-body preparations. Novel discoveries…”
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A Review of Personalised Cardiac Computational Modelling Using Electroanatomical Mapping Data
Published in Arrhythmia & electrophysiology review (20-05-2024)“…Computational models of cardiac electrophysiology have gradually matured during the past few decades and are now being personalised to provide patient-specific…”
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Microdroplet formation in rounded flow-focusing junctions
Published in Microfluidics and nanofluidics (2016)“…Herein we report microfluidic droplet formation in flow-focusing geometries possessing varying degrees of rounding. Rounding is incorporated in all four…”
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Improving Generalization by Learning Geometry-Dependent and Physics-Based Reconstruction of Image Sequences
Published in IEEE transactions on medical imaging (01-02-2023)“…Deep neural networks have shown promise in image reconstruction tasks, although often on the premise of large amounts of training data. In this paper, we…”
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Estimation and Validation of Cardiac Conduction Velocity and Wavefront Reconstruction Using Epicardial and Volumetric Data
Published in IEEE transactions on biomedical engineering (01-11-2021)“…Objective: In this study, we have used whole heart simulations parameterized with large animal experiments to validate three techniques (two from the…”
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Treatment of pathophysiologic propagation outside of the pulmonary veins in retreatment of atrial fibrillation patients: RECOVER AF study
Published in Europace (London, England) (19-05-2023)“…Abstract Aims RECOVER AF evaluated the performance of whole-chamber non-contact charge-density mapping to guide the ablation of non-pulmonary vein (PV) targets…”
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Novel experimental model for studying the spatiotemporal electrical signature of acute myocardial ischemia: a translational platform
Published in Physiological measurement (05-02-2020)“…Myocardial ischemia is one of the most common cardiovascular pathologies and can indicate many severe and life threatening diseases. Despite these risks,…”
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The electrocardiographic forward problem: A benchmark study
Published in Computers in biology and medicine (01-07-2021)“…Electrocardiographic forward problems are crucial components for noninvasive electrocardiographic imaging (ECGI) that compute torso potentials from cardiac…”
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Reconstruction of cardiac position using body surface potentials
Published in Computers in biology and medicine (01-03-2022)“…Electrocardiographic imaging (ECGI) is a noninvasive technique to assess the bioelectric activity of the heart which has been applied to aid in clinical…”
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PFEIFER: A MATLAB Based Platform for Preprocessing and Autofiducializing Experimental Electrogram Recordings
Published in Journal of electrocardiology (01-11-2019)“…Background: Time signals recorded from experiments in cardiac electrophysiology require processing before further analysis and interpretation. Most labs create…”
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A Framework for Image-Based Modeling of Acute Myocardial Ischemia Using Intramurally Recorded Extracellular Potentials
Published in Annals of biomedical engineering (01-09-2018)“…The biophysical basis for electrocardiographic evaluation of myocardial ischemia stems from the notion that ischemic tissues develop, with relative uniformity,…”
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Transient recovery of epicardial and torso ST-segment ischemic signals during cardiac stress tests: A possible physiological mechanism
Published in Journal of electrocardiology (01-11-2021)“…Acute myocardial ischemia has several characteristic ECG findings, including clinically detectable ST-segment deviations. However, the sensitivity and…”
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Combining endocardial mapping and electrocardiographic imaging (ECGI) for improving PVC localization: A feasibility study
Published in Journal of electrocardiology (01-11-2021)“…Accurate reconstruction of cardiac activation wavefronts is crucial for clinical diagnosis, management, and treatment of cardiac arrhythmias. Furthermore,…”
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Temporal Performance of Laplacian Eigenmaps and 3D Conduction Velocity in Detecting Ischemic Stress
Published in Journal of electrocardiology (01-11-2018)“…Myocardial ischemia has a complex and time-varying electrocardiographic signature that is used to diagnose and stratify severity. Despite the ubiquitous…”
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Pharmacological and simulated exercise cardiac stress tests produce different ischemic signatures in high-resolution experimental mapping studies
Published in Journal of electrocardiology (01-09-2021)“…Test the hypothesis that exercise and pharmacological cardiac stressors create different electrical ischemic signatures. Current clinical stress tests for…”
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Novel Metric for Evaluating Ischemic Stress in Electrograms Using a Data-Driven Approach
Published in Journal of electrocardiology (01-11-2019)“…Background: The underlying pathophysiology of ischemia is incompletely understood, resulting in persistent difficulty of diagnosis. This limited understanding…”
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Quantifying the spatiotemporal influence of acute myocardial ischemia on volumetric conduction velocity
Published in Journal of electrocardiology (01-05-2021)“…Acute myocardial ischemia occurs when coronary perfusion to the heart is inadequate, which can perturb the highly organized electrical activation of the heart…”
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PFEIFER: Preprocessing Framework for Electrograms Intermittently Fiducialized from Experimental Recordings
Published in Journal of open source software (01-01-2018)Get full text
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Improved Non-Contact Heart Chamber Modeling Using Catheter Mediated Ultrasound Returns
Published in 2022 Computing in Cardiology (CinC) (04-09-2022)“…Non-contact (inverse) techniques for mapping of cardiac electrical activity require the existence of an accurate surface representation, typically in the form…”
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Conference Proceeding -
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High-Capacity Cardiac Signal Acquisition System for Flexible, Simultaneous, Multidomain Acquisition
Published in 2020 Computing in Cardiology (01-09-2020)“…Capturing cardiac electrical propagation or electrocardiographic images demands simultaneous, multidomain recordings of electrocardiographic signals with…”
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Conference Proceeding Journal Article