Search Results - "Good, Lydia L."

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    Rapid protein stability prediction using deep learning representations by Blaabjerg, Lasse M, Kassem, Maher M, Good, Lydia L, Jonsson, Nicolas, Cagiada, Matteo, Johansson, Kristoffer E, Boomsma, Wouter, Stein, Amelie, Lindorff-Larsen, Kresten

    Published in eLife (15-05-2023)
    “…Predicting the thermodynamic stability of proteins is a common and widely used step in protein engineering, and when elucidating the molecular mechanisms…”
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    The cofactor-dependent folding mechanism of Drosophila cryptochrome revealed by single-molecule pulling experiments by Foroutannejad, Sahar, Good, Lydia L., Lin, Changfan, Carter, Zachariah I., Tadesse, Mahlet G., Lucius, Aaron L., Crane, Brian R., Maillard, Rodrigo A.

    Published in Nature communications (24-02-2023)
    “…The link between cofactor binding and protein activity is well-established. However, how cofactor interactions modulate folding of large proteins remains…”
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    Protein Condensate Atlas from predictive models of heteromolecular condensate composition by Saar, Kadi L., Scrutton, Rob M., Bloznelyte, Kotryna, Morgunov, Alexey S., Good, Lydia L., Lee, Alpha A., Teichmann, Sarah A., Knowles, Tuomas P. J.

    Published in Nature communications (10-07-2024)
    “…Biomolecular condensates help cells organise their content in space and time. Cells harbour a variety of condensate types with diverse composition and many are…”
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    Theoretical and Data-Driven Approaches for Biomolecular Condensates by Saar, Kadi L., Qian, Daoyuan, Good, Lydia L., Morgunov, Alexey S., Collepardo-Guevara, Rosana, Best, Robert B., Knowles, Tuomas P. J.

    Published in Chemical reviews (26-07-2023)
    “…Biomolecular condensation processes are increasingly recognized as a fundamental mechanism that living cells use to organize biomolecules in time and space…”
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    Conformational changes in protein kinase A along its activation cycle are rooted in the folding energetics of cyclic-nucleotide binding domains by Chau, Amy K., Bracken, Katherine, Bai, Lihui, Pham, Dominic, Good, Lydia L., Maillard, Rodrigo A.

    Published in The Journal of biological chemistry (01-06-2023)
    “…Cyclic-nucleotide binding (CNB) domains are structurally and evolutionarily conserved signaling modules that regulate proteins with diverse folds and…”
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