Search Results - "Good, Lydia L."
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A structural biology community assessment of AlphaFold2 applications
Published in Nature structural & molecular biology (01-11-2022)“…Most proteins fold into 3D structures that determine how they function and orchestrate the biological processes of the cell. Recent developments in…”
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Rapid protein stability prediction using deep learning representations
Published in eLife (15-05-2023)“…Predicting the thermodynamic stability of proteins is a common and widely used step in protein engineering, and when elucidating the molecular mechanisms…”
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The cofactor-dependent folding mechanism of Drosophila cryptochrome revealed by single-molecule pulling experiments
Published in Nature communications (24-02-2023)“…The link between cofactor binding and protein activity is well-established. However, how cofactor interactions modulate folding of large proteins remains…”
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Protein Condensate Atlas from predictive models of heteromolecular condensate composition
Published in Nature communications (10-07-2024)“…Biomolecular condensates help cells organise their content in space and time. Cells harbour a variety of condensate types with diverse composition and many are…”
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Theoretical and Data-Driven Approaches for Biomolecular Condensates
Published in Chemical reviews (26-07-2023)“…Biomolecular condensation processes are increasingly recognized as a fundamental mechanism that living cells use to organize biomolecules in time and space…”
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Conformational changes in protein kinase A along its activation cycle are rooted in the folding energetics of cyclic-nucleotide binding domains
Published in The Journal of biological chemistry (01-06-2023)“…Cyclic-nucleotide binding (CNB) domains are structurally and evolutionarily conserved signaling modules that regulate proteins with diverse folds and…”
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Statistical and Biophysical Analysis of Force-Pulling Optical Tweezers Data in Complex Protein Systems
Published in Biophysical journal (12-02-2021)Get full text
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