Search Results - "Good, Liam"

Genetic evidence for inhibition of bacterial division protein FtsZ by berberine by Boberek, Jaroslaw M, Stach, Jem, Good, Liam

“…Berberine is a plant alkaloid that is widely used as an anti-infective in traditional medicine. Escherichia coli exposed to berberine form filaments,…”
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Fungal cell barriers and organelles are disrupted by polyhexamethylene biguanide (PHMB) by Ntow-Boahene, Winnie, Papandronicou, Isabelle, Miculob, Josephous, Good, Liam

“…The similarities between fungal and mammalian cells pose inherent challenges for the development of treatments for fungal infections, due to drug crossover…”
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The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes by Chindera, Kantaraja, Mahato, Manohar, Kumar Sharma, Ashwani, Horsley, Harry, Kloc-Muniak, Klaudia, Kamaruzzaman, Nor Fadhilah, Kumar, Satish, McFarlane, Alexander, Stach, Jem, Bentin, Thomas, Good, Liam

“…To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial…”
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Doxycycline induces Hok toxin killing in host E. coli by Chukwudi, Chinwe Uzoma, Good, Liam, Cartelle Gestal, Monica

“…The antibacterial efficacy of the tetracycline antibiotics has been greatly reduced by the development of resistance, hence a decline in their clinical use…”
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Chaperonins Fight Aminoglycoside-induced Protein Misfolding and Promote Short-term Tolerance in Escherichia coli by Goltermann, Lise, Good, Liam, Bentin, Thomas

“…For almost half of a century, we have known that aminoglycoside antibiotics corrupt ribosomes, causing translational misreading, yet it remains unclear whether…”
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Identification of Escherichia coli from broiler chickens in Jordan, their antimicrobial resistance, gene characterization and the associated risk factors by Ibrahim, Rekaz A, Cryer, Tillie L, Lafi, Shawkat Q, Basha, Ehab-Abu, Good, Liam, Tarazi, Yaser H

“…Avian pathogenic Escherichia coli (APEC) is the principle cause of colibacillosis affecting poultry. The main challenge to the poultry industry is…”
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Antifungal Polymeric Materials and Nanocomposites by Ntow-Boahene, Winnie, Cook, David, Good, Liam

“…Rising global populations due to medicinal advancements increases the patient population susceptible to superficial and severe fungal infections. Fungi often…”
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Doxycycline inhibits pre-rRNA processing and mature rRNA formation in E. coli by Chukwudi, Chinwe U., Good, Liam

“…In bacteria, RNase III cleaves the initial long primary ribosomal RNA transcripts/precursors (pre-rRNAs), thereby releasing the pre-16S and pre-23S rRNAs for…”
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Polyhexamethylene Biguanide:Polyurethane Blend Nanofibrous Membranes for Wound Infection Control by Worsley, Anna, Vassileva, Kristin, Tsui, Janice, Song, Wenhui, Good, Liam

“…Polyhexamethylene biguanide (PHMB) is a broad-spectrum antiseptic which avoids many efficacy and toxicity problems associated with antimicrobials, in…”
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Species-selective killing of bacteria by antimicrobial peptide-PNAs by Mondhe, Madhav, Chessher, Ashley, Goh, Shan, Good, Liam, Stach, James E M

“…Broad-spectrum antimicrobials kill indiscriminately, a property that can lead to negative clinical consequences and an increase in the incidence of resistance…”
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Antimicrobial activities of polyhexamethylene biguanide against biofilm-producing Prototheca bovis causing bovine mastitis by Fidelis, Carlos Eduardo, de Freitas Leite, Renata, Garcia, Breno Luis Nery, Gonçalves, Juliano Leonel, Good, Liam, dos Santos, Marcos Veiga

“…Prototheca spp. is a frequent cause of bovine mastitis and is highly resistant to commonly used disinfectants. This study aimed to: (1) evaluate the…”
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Interaction of the tetracyclines with double-stranded RNAs of random base sequence: new perspectives on the target and mechanism of action by Chukwudi, Chinwe U, Good, Liam

“…The 16S rRNA binding mechanism proposed for the antibacterial action of the tetracyclines does not explain their mechanism of action against non-bacterial…”
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Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis by Kamaruzzaman, Nor F, Chong, Stacy Q Y, Edmondson-Brown, Kamina M, Ntow-Boahene, Winnie, Bardiau, Marjorie, Good, Liam

“…infection is a common cause of mastitis, reducing milk yield, affecting animal welfare and causing huge economic losses within the dairy industry. In addition…”
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The role of the hok/sok locus in bacterial response to stressful growth conditions by Chukwudi, Chinwe U., Good, Liam

“…The hok/sok locus is renowned for its plasmid stabilization effect via post-segregational killing of plasmid-free daughter cells. However, the function(s) of…”
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FtsE, the Nucleotide Binding Domain of the ABC Transporter Homolog FtsEX, Regulates Septal PG Synthesis in E. coli by Mallik, Sunanda, Dodia, Hiren, Ghosh, Arup, Srinivasan, Ramanujam, Good, Liam, Raghav, Sunil Kumar, Beuria, Tushar Kant

“…The peptidoglycan (PG) layer, a crucial component of the tripartite envelope, is required to maintain cellular integrity, protecting the cells from mechanical…”
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The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function by Scheele, Camilla, Petrovic, Natasa, Faghihi, Mohammad A, Lassmann, Timo, Fredriksson, Katarina, Rooyackers, Olav, Wahlestedt, Claes, Good, Liam, Timmons, James A

“…Mutations in the PTEN induced putative kinase 1 (PINK1) are implicated in early-onset Parkinson's disease. PINK1 is expressed abundantly in mitochondria rich…”
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Genetic diversity and risk factors for the transmission of antimicrobial resistance across human, animals and environmental compartments in East Africa: a review by Katale, Bugwesa Z, Misinzo, Gerald, Mshana, Stephen E, Chiyangi, Harriet, Campino, Susana, Clark, Taane G, Good, Liam, Rweyemamu, Mark M, Matee, Mecky I

“…Abstract Background The emergence and spread of antimicrobial resistance (AMR) present a challenge to disease control in East Africa. Resistance to…”
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The development of species-specific antisense peptide nucleic acid method for the treatment and detection of viable Salmonella by Adebowale, Oluwawemimo O., Goh, Shan, Good, Liam

“…Genotypic based detection methods using specific target sites in the pathogen genome can complement phenotypic identification. We report the development of…”
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The Effects of Polyhexamethylene Biguanide (PHMB) and TLR Agonists Alone or as Polyplex Nanoparticles against Leishmania infantum Promastigotes and Amastigotes by Martínez-Orellana, Pamela, Baxarias, Marta, Good, Liam, Solano-Gallego, Laia

“…Dogs are the main reservoir for manifesting from a subclinical to a fatal disease. Limited treatments are available, although new antiparasitics and…”
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The mazEF toxin-antitoxin system as a novel antibacterial target in Acinetobacter baumannii by Ghafourian, Sobhan, Good, Liam, Sekawi, Zamberi, Hamat, Rukman Awang, Soheili, Sara, Sadeghifard, Nourkhoda, Neela, Vasanthakumari

“…Although analysis of toxin-antitoxin (TA) systems can be instructive, to date, there is no information on the prevalence and identity of TA systems based on a…”
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