Search Results - "Gooch, J."

Fibers in the Extracellular Matrix Enable Long-Range Stress Transmission between Cells by Ma, Xiaoyue, Schickel, Maureen E., Stevenson, Mark D., Sarang-Sieminski, Alisha L., Gooch, Keith J., Ghadiali, Samir N., Hart, Richard T.

“…Cells can sense, signal, and organize via mechanical forces. The ability of cells to mechanically sense and respond to the presence of other cells over…”
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Direct influence of culture dimensionality on human mesenchymal stem cell differentiation at various matrix stiffnesses using a fibrous self-assembling peptide hydrogel by Hogrebe, Nathaniel J., Gooch, Keith J.

“…Much is unknown about the effects of culture dimensionality on cell behavior due to the lack of biomimetic substrates that are suitable for directly comparing…”
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Neurodivergence and radiology: How medical professionals can optimise the standard of care provided to autistic paediatric patients by Marterosyan, J., Gooch, J.

“…Several studies have been published regarding patients with various neurodevelopmental diagnoses attending hospital appointments, however, few focus on autism…”
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Biomaterial microarchitecture: a potent regulator of individual cell behavior and multicellular organization by Hogrebe, Nathaniel J., Reinhardt, James W., Gooch, Keith J.

“…Insoluble cues from a cell's surrounding microenvironment have increasingly been shown to be important regulators of cell behavior. The microarchitecture of…”
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Behavior Change Approaches in Digital Technology-Based Physical Rehabilitation Interventions Following Stroke: Scoping Review by Gooch, Helen J, Jarvis, Kathryn A, Stockley, Rachel C

“…Digital health technologies (DHTs) are increasingly used in physical stroke rehabilitation to support individuals in successfully engaging with the frequent,…”
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Decreased Substrate Stiffness Promotes a Hypofibrotic Phenotype in Cardiac Fibroblasts by Childers, Rachel C., Lucchesi, Pamela A., Gooch, Keith J.

“…A hypofibrotic phenotype has been observed in cardiac fibroblasts (CFs) isolated from a volume overload heart failure model, aortocaval fistula (ACF). This…”
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Endothelial actin and cell stiffness is modulated by substrate stiffness in 2D and 3D by Byfield, Fitzroy J, Reen, Rashmeet K, Shentu, Tzu-Pin, Levitan, Irena, Gooch, Keith J

“…Abstract There is a growing appreciation of the profound effects that passive mechanical properties, especially the stiffness of the local environment, can…”
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Home-based exercise for people living with frailty and chronic kidney disease: A mixed-methods pilot randomised controlled trial by Nixon, Andrew C, Bampouras, Theodoros M, Gooch, Helen J, Young, Hannah M. L, Finlayson, Kenneth W, Pendleton, Neil, Mitra, Sandip, Brady, Mark E, Dhaygude, Ajay P

“…Background Frailty is associated with adverse health outcomes in people with chronic kidney disease (CKD). Evidence supporting targeted interventions is…”
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α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site by Miroshnikova, Y A, Rozenberg, G I, Cassereau, L, Pickup, M, Mouw, J K, Ou, G, Templeman, K L, Hannachi, E-I, Gooch, K J, Sarang-Sieminski, A L, García, A J, Weaver, V M

“…Tumors are fibrotic and characterized by abundant, remodeled, and cross-linked collagen that stiffens the extracellular matrix stroma. The stiffened…”
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A growing threat to the ozone layer from short-lived anthropogenic chlorocarbons by Oram, David E, Ashfold, Matthew J, Laube, Johannes C, Gooch, Lauren J, Humphrey, Stephen, Sturges, William T, Leedham-Elvidge, Emma, Forster, Grant L, Harris, Neil R. P, Mead, Mohammed Iqbal, Samah, Azizan Abu, Phang, Siew Moi, Ou-Yang, Chang-Feng, Lin, Neng-Huei, Wang, Jia-Lin, Baker, Angela K, Brenninkmeijer, Carl A. M, Sherry, David

“…Large and effective reductions in emissions of long-lived ozone-depleting substance (ODS) are being achieved through the Montreal Protocol, the effectiveness…”
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real‐time qPCR assay for the detection of the nifH gene of Methanobrevibacter smithii, a potential indicator of sewage pollution by Johnston, C, Ufnar, J.A, Griffith, J.F, Gooch, J.A, Stewart, J.R

“…Aims: To develop a quantitative, real‐time PCR assay to detect the nifH gene of Methanobrevibacter smithii. Methanobrevibacter smithii is a methanogenic…”
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Solid-phase synthesis of Rhodamine-110 fluorogenic substrates and their application in forensic analysis by Gooch, J, Abbate, V, Daniel, B, Frascione, N

“…A novel synthetic route for the rapid and efficient preparation of fluorogenic substrates utilizing Rhodamine-110 or similar fluorophores is reported…”
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The Collaborative Cross as a Resource for Modeling Human Disease: CC011/Unc, a New Mouse Model for Spontaneous Colitis by Rogala, Allison R., Morgan, Andrew P., Christensen, Alexis M., Gooch, Terry J., Bell, Timothy A., Miller, Darla R., Godfrey, Virginia L., de Villena, Fernando Pardo-Manuel

“…Inflammatory bowel disease (IBD) is an immune-mediated condition driven by improper responses to intestinal microflora in the context of environmental and…”
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Trends and emissions of six perfluorocarbons in the Northern Hemisphere and Southern Hemisphere by Droste, Elise S, Adcock, Karina E, Ashfold, Matthew J, Chou, Charles, Fleming, ZoÃ, Fraser, Paul J, Gooch, Lauren J, Hind, Andrew J, Langenfelds, Ray L, Leedham Elvidge, Emma, Mohd Hanif, Norfazrin, O'Doherty, Simon, Oram, David E, Ou-Yang, Chang-Feng, Panagi, Marios, Reeves, Claire E, Sturges, William T, Laube, Johannes C

“…Perfluorocarbons (PFCs) are potent greenhouse gases with global warming potentials up to several thousand times greater than CO2 on a 100-year time horizon…”
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Pericellular Conditions Regulate Extent of Cell-Mediated Compaction of Collagen Gels by Stevenson, Mark D., Sieminski, Alisha L., McLeod, Claire M., Byfield, Fitzroy J., Barocas, Victor H., Gooch, Keith J.

“…Cell-mediated compaction of the extracellular matrix (ECM) plays a critical role in tissue engineering, wound healing, embryonic development, and many disease…”
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The EX-FRAIL CKD trial: a study protocol for a pilot randomised controlled trial of a home-based EXercise programme for pre-frail and FRAIL, older adults with Chronic Kidney Disease by Nixon, Andrew Christopher, Bampouras, Theodoros M, Gooch, Helen J, Young, Hannah M L, Finlayson, Kenneth William, Pendleton, Neil, Mitra, Sandip, Brady, Mark E, Dhaygude, Ajay P

“…IntroductionFrailty is highly prevalent in adults with chronic kidney disease (CKD) and is associated with adverse health outcomes including falls, poorer…”
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Continued increase of CFC-113a (CCl 3 CF 3 ) mixing ratios in the global atmosphere: emissions, occurrence and potential sources by Adcock, Karina E., Reeves, Claire E., Gooch, Lauren J., Leedham Elvidge, Emma C., Ashfold, Matthew J., Brenninkmeijer, Carl A. M., Chou, Charles, Fraser, Paul J., Langenfelds, Ray L., Mohd Hanif, Norfazrin, O'Doherty, Simon, Oram, David E., Ou-Yang, Chang-Feng, Phang, Siew Moi, Samah, Azizan Abu, Röckmann, Thomas, Sturges, William T., Laube, Johannes C.

“…Atmospheric measurements of the ozone-depleting substance CFC-113a (CCl3CF3) are reported from ground-based stations in Australia, Taiwan, Malaysia and the…”
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Temporal and Environmental Factors Driving Vibrio Vulnificus and V. Parahaemolyticus Populations and Their Associations With Harmful Algal Blooms in South Carolina Detention Ponds and Receiving Tidal Creeks by Greenfield, D. I., Gooch Moore, J., Stewart, J. R., Hilborn, E. D., George, B. J., Li, Q., Dickerson, J., Keppler, C. K., Sandifer, P. A.

“…Incidences of harmful algal blooms (HABs) and Vibrio infections have increased over recent decades. Numerous studies have tried to identify environmental…”
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IPD1.01 Non-tuberculous mycobacteria infection in children with cystic fibrosis – experience from a large tertiary centre in United Kingdom by Gooch, J, Turnbull, L, Fullwood, C, Maitra, A

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Arterial levels of oxygen stimulate intimal hyperplasia in human saphenous veins via a ROS-dependent mechanism by Joddar, Binata, Firstenberg, Michael S, Reen, Rashmeet K, Varadharaj, Saradhadevi, Khan, Mahmood, Childers, Rachel C, Zweier, Jay L, Gooch, Keith J

“…Saphenous veins used as arterial grafts are exposed to arterial levels of oxygen partial pressure (pO2), which are much greater than what they experience in…”
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