Search Results - "Goo Taeg, Oh"
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Pancreatic β-cell mitophagy as an adaptive response to metabolic stress and the underlying mechanism that involves lysosomal Ca2+ release
Published in Experimental & molecular medicine (01-09-2023)“…Mitophagy is an excellent example of selective autophagy that eliminates damaged or dysfunctional mitochondria, and it is crucial for the maintenance of…”
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2
NAA10 controls osteoblast differentiation and bone formation as a feedback regulator of Runx2
Published in Nature communications (07-11-2014)“…Runt-related transcription factor 2 (Runx2) transactivates many genes required for osteoblast differentiation. The role of N -α-acetyltransferase 10 (NAA10,…”
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3
Active Intestinal Calcium Transport in the Absence of Transient Receptor Potential Vanilloid Type 6 and Calbindin-D9k
Published in Endocrinology (Philadelphia) (01-06-2008)“…To study the role of the epithelial calcium channel transient receptor potential vanilloid type 6 (TRPV6) and the calcium-binding protein calbindin-D9k in…”
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4
Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm
Published in Experimental & molecular medicine (01-09-2020)“…Abdominal aortic aneurysm (AAA) is an inflammatory vascular disease characterized by structural deterioration of the aorta caused by inflammation and oxidative…”
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5
The role of peroxidases in the pathogenesis of atherosclerosis
Published in BMB reports (01-08-2011)“…Reactive oxygen species (ROS), which include superoxide anions and peroxides, induce oxidative stress, contributing to the initiation and progression of…”
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6
The adipokine Retnla deficiency increases responsiveness to cardiac repair through adiponectin-rich bone marrow cells
Published in Cell death & disease (22-03-2021)“…Resistin-like alpha (Retnla) is a member of the resistin family and known to modulate fibrosis and inflammation. Here, we investigated the role of Retnla in…”
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7
Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts
Published in Experimental & molecular medicine (16-01-2019)“…Osteoclasts (OCs) are bone-resorbing cells that originate from hematopoietic stem cells and develop through the fusion of mononuclear myeloid precursors…”
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8
Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway
Published in eLife (06-08-2021)“…Amino-terminal acetylation is catalyzed by a set of N-terminal acetyltransferases (NATs). The NatA complex (including X-linked Naa10 and Naa15) is the major…”
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Fenofibrate differentially regulates plasminogen activator inhibitor‐1 gene expression via adenosine monophosphate–activated protein kinase–dependent induction of orphan nuclear receptor small heterodimer partner
Published in Hepatology (Baltimore, Md.) (01-09-2009)“…Plasminogen activator inhibitor type I (PAI‐1) is a marker of the fibrinolytic system and serves as a possible predictor for hepatic metabolic syndromes…”
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10
Peroxisomal Fitness: A Potential Protective Mechanism of Fenofibrate against High Fat Diet-Induced Non- Alcoholic Fatty Liver Disease in Mice
Published in Diabetes & metabolism journal (30-11-2022)“…Background: Non-alcoholic fatty liver disease (NAFLD) has been increasing in association with the epidemic of obesity and diabetes. Peroxisomes are single…”
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11
Functional and clinical evidence for NDRG2 as a candidate suppressor of liver cancer metastasis
Published in Cancer research (Chicago, Ill.) (01-06-2008)“…We searched for potential suppressors of tumor metastasis by identifying the genes that are frequently down-regulated in hepatocellular carcinomas (HCC) while…”
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12
Regulation of IGFBP-2 expression during fasting
Published in Biochemical journal (01-05-2015)“…Insulin-like growth factor (IGF)-binding protein-2 (IGFBP-2), one of the most abundant circulating IGFBPs, is known to attenuate the biological action of…”
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13
Phenotype of a Calbindin‐D9k Gene Knockout Is Compensated for by the Induction of Other Calcium Transporter Genes in a Mouse Model
Published in Journal of bone and mineral research (01-12-2007)“…CaBP‐9k may be involved in the active calcium absorption and embryo implantation. Although we generated CaBP‐9k KO mice to explore its function, no distinct…”
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14
Extract of high hydrostatic pressure-treated danshen (Salvia miltiorrhiza) ameliorates atherosclerosis via autophagy induction
Published in BMB reports (31-12-2020)“…Danshen (Salvia miltiorrhiza) is a traditional medicinal plant widely used in Asian countries for its pharmacological activities (e.g., amelioration of…”
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15
Vimentin Deficiency Prevents High-Fat Diet-Induced Obesity and Insulin Resistance in Mice
Published in Diabetes & metabolism journal (31-01-2021)“…Background: Obesity and type 2 diabetes mellitus are world-wide health problems, and lack of understanding of their linking mechanism is one reason for limited…”
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16
Combined application of rapamycin and atorvastatin improves lipid metabolism in apolipoprotein E-deficient mice with chronic kidney disease
Published in BMB reports (31-03-2021)“…Atherosclerosis arising from the pro-inflammatory conditions associated with chronic kidney disease (CKD) increases major cardiovascular morbidity and…”
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Hepatocyte Growth Factor Suppresses Vascular Endothelial Growth Factor–Induced Expression of Endothelial ICAM-1 and VCAM-1 by Inhibiting the Nuclear Factor-κB Pathway
Published in Circulation research (18-02-2005)“…Vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) are potent angiogenic factors that have been used clinically to induce…”
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18
α-Lipoic Acid Prevents Endothelial Dysfunction in Obese Rats via Activation of AMP-Activated Protein Kinase
Published in Arteriosclerosis, thrombosis, and vascular biology (01-12-2005)“…OBJECTIVE—Lipid accumulation in vascular endothelial cells may play an important role in the pathogenesis of atherosclerosis in obese subjects. We showed…”
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Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models
Published in Circulation research (26-10-2018)“…Monocyte infiltration into the subintimal space and its intracellular lipid accumulation are the most prominent features of atherosclerosis. To understand the…”
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Ginseng Berry Extract Prevents Atherogenesis via Anti-Inflammatory Action by Upregulating Phase II Gene Expression
Published in Evidence-based complementary and alternative medicine (01-01-2012)“…Ginseng berry possesses higher ginsenoside content than its root, which has been traditionally used in herbal medicine for many human diseases, including…”
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