Search Results - "Gonzalez, Lauren E."

The Upstream Sequence Transcription Complex dictates nucleosome positioning and promoter accessibility at piRNA genes in the C. elegans germ line by Paniagua, Nancy, Roberts, C Jackson, Gonzalez, Lauren E, Monedero-Alonso, David, Reinke, Valerie

“…The piRNA pathway is a conserved germline-specific small RNA pathway that ensures genomic integrity and continued fertility. In C. elegans and other nematodes,…”
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Transcriptome analysis uncovers Arabidopsis F-BOX STRESS INDUCED 1 as a regulator of jasmonic acid and abscisic acid stress gene expression by Gonzalez, Lauren E, Keller, Kristen, Chan, Karen X, Gessel, Megan M, Thines, Bryan C

“…The ubiquitin 26S proteasome system (UPS) selectively degrades cellular proteins, which results in physiological changes to eukaryotic cells. F-box proteins…”
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Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo by May, Dennis, Yun, Sangwon, Gonzalez, David G, Park, Sangbum, Chen, Yanbo, Lathrop, Elizabeth, Cai, Biao, Xin, Tianchi, Zhao, Hongyu, Wang, Siyuan, Gonzalez, Lauren E, Cockburn, Katie, Greco, Valentina

“…Stem cell differentiation requires dramatic changes in gene expression and global remodeling of chromatin architecture. How and when chromatin remodels…”
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Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA by Zhang, Jun, McCann, Kathleen L., Qiu, Chen, Gonzalez, Lauren E., Baserga, Susan J., Hall, Traci M. Tanaka

“…Numerous factors direct eukaryotic ribosome biogenesis, and defects in a single ribosome assembly factor may be lethal or produce tissue-specific human…”
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Maternal Piwi regulates primordial germ cell development to ensure the fertility of female progeny in Drosophila by Gonzalez, Lauren E, Tang, Xiongzhuo, Lin, Haifan

“…Abstract In many animals, germline development is initiated by proteins and RNAs that are expressed maternally. PIWI proteins and their associated small…”
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The art of observation: bridging science and art to see the unexpected by Gonzalez, Lauren E, Wei, Haoyang, Greco, Valentina, Friedlaender, Linda K

“…Observation is the heart of research, but it can be challenging to observe deeply and go beyond expected observations. Here, we describe activities designed…”
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Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis by Mazzetto, Mariateresa, Gonzalez, Lauren E, Sanchez, Nancy, Reinke, Valerie

“…Chromatin organization in the germline is tightly regulated and critical for germ cell differentiation. Although certain germline epigenetic regulatory…”
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Organ function is preserved despite reorganization of niche architecture in the hair follicle by Wei, Haoyang, Du, Shuangshuang, Parksong, Jeeun, Pasolli, H. Amalia, Matte-Martone, Catherine, Regot, Sergi, Gonzalez, Lauren E., Xin, Tianchi, Greco, Valentina

“…The ability of stem cells to build and replenish tissues depends on support from their niche. Although niche architecture varies across organs, its functional…”
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Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation by Xin, Tianchi, Gallini, Sara, Wei, Haoyang, Gonzalez, David G., Matte-Martone, Catherine, Machida, Hiroki, Fujiwara, Hironobu, Pasolli, H. Amalia, Suozzi, Kathleen C., Gonzalez, Lauren E., Regot, Sergi, Greco, Valentina

“…Tissue regeneration and maintenance rely on coordinated stem cell behaviours. This orchestration can be impaired by oncogenic mutations leading to cancer…”
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Nop9 recognizes structured and single-stranded RNA elements of preribosomal RNA by Zhang, Jun, Teramoto, Takamasa, Qiu, Chen, Wine, Robert N, Gonzalez, Lauren E, Baserga, Susan J, Tanaka Hall, Traci M

“…Nop9 is an essential factor in the processing of preribosomal RNA. Its absence in yeast is lethal, and defects in the human ortholog are associated with breast…”
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Structural analysis reveals the flexible C-terminus of Nop15 undergoes rearrangement to recognize a pre-ribosomal RNA folding intermediate by Zhang, Jun, Gonzalez, Lauren E, Hall, Traci M Tanaka

“…The RNA recognition motif (RRM) is the most abundant RNA-binding domain in eukaryotes, and it plays versatile roles in RNA metabolism. Despite its abundance,…”
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Evening Emergence Behavior and Seasonal Dynamics in Large Colonies of Brazilian Free-tailed Bats by Reichard, Jonathan D., Gonzalez, Lauren E., Casey, Caitlin M., Allen, Louise C., Hristov, Nickolay I., Kunz, Thomas H.

“…Flexible behaviors permit gregarious animals to exploit spatially and temporally favorable conditions for reproduction. Evening emergences of Brazilian…”
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Ovarian somatic Piwi regulates nurse cell proliferation and oocyte specification in Drosophila by Gonzalez, Lauren E, Zhu, Gina, Lin, Haifan

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Piwi in the stem cell niche regulates nurse cell number and oocyte specification by Zhu, Gina, Gonzalez, Lauren E, Lin, Haifan

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Nop9 recognizes structured and single-stranded RNA elements of preribosomal RNA by Zhang, Jun, Teramoto, Takamasa, Qiu, Chen, Wine, Robert N., Gonzalez, Lauren E., Baserga, Susan J., Hall, Traci M. Tanaka

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New Roles for Small Noncoding RNAs in Germline Development: Maternal Piwi and piRNAs Specifically Protect the Fertility of Female Progeny by Gonzalez, Lauren E

“…The long-term survival of a species depends on the integrity of its genetic material and the inheritance of that genetic material across generations. In…”
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