Search Results - "Gonzalez, Iveth J"
-
1
Host Biomarkers for Distinguishing Bacterial from Non-Bacterial Causes of Acute Febrile Illness: A Comprehensive Review
Published in PloS one (03-08-2016)“…In resource limited settings acute febrile illnesses are often treated empirically due to a lack of reliable, rapid point-of-care diagnostics. This contributes…”
Get full text
Journal Article -
2
Thermal Contrast Amplification Reader Yielding 8‑Fold Analytical Improvement for Disease Detection with Lateral Flow Assays
Published in Analytical chemistry (Washington) (06-12-2016)“…There is an increasing need for highly sensitive and quantitative diagnostics at the point-of-care. The lateral flow immunoassay (LFA) is one of the most…”
Get full text
Journal Article -
3
A Systematic Review: Performance of Rapid Diagnostic Tests for the Detection of Plasmodium knowlesi, Plasmodium malariae, and Plasmodium ovale Monoinfections in Human Blood
Published in The Journal of infectious diseases (20-06-2018)“…This work summarizes the available data on the performance of rapid diagnostic tests (RDTs) for the detection of monoinfections due to Plasmodium species P…”
Get full text
Journal Article -
4
Tools for surveillance of anti-malarial drug resistance: an assessment of the current landscape
Published in Malaria journal (08-02-2018)“…To limit the spread and impact of anti-malarial drug resistance and react accordingly, surveillance systems able to detect and track in real-time its emergence…”
Get full text
Journal Article -
5
Performance of a highly sensitive rapid diagnostic test (HS-RDT) for detecting malaria in peripheral and placental blood samples from pregnant women in Colombia
Published in PloS one (02-08-2018)“…Pregnancy poses specific challenges for the diagnosis of Plasmodium falciparum infection due to parasite sequestration in the placenta, which translates in low…”
Get full text
Journal Article -
6
Development and validation of serological markers for detecting recent Plasmodium vivax infection
Published in Nature Medicine (01-05-2020)“…A major gap in the Plasmodium vivax elimination toolkit is the identification of individuals carrying clinically silent and undetectable liver-stage parasites,…”
Get full text
Journal Article Magazine Article -
7
Diagnostic accuracy of loop-mediated isothermal amplification (LAMP) for screening malaria in peripheral and placental blood samples from pregnant women in Colombia
Published in Malaria journal (13-07-2018)“…Pregnant women frequently show low-density Plasmodium infections that require more sensitive methods for accurate diagnosis and early treatment of malaria…”
Get full text
Journal Article -
8
Detection of Plasmodium knowlesi, Plasmodium falciparum and Plasmodium vivax using loop-mediated isothermal amplification (LAMP) in a co-endemic area in Malaysia
Published in Malaria journal (13-01-2017)“…Plasmodium knowlesi is the most common cause of malaria in Malaysia. However, microscopic diagnosis is inaccurate and rapid diagnostic tests (RDTs) are…”
Get full text
Journal Article -
9
Global survey of malaria rapid diagnostic test (RDT) sales, procurement and lot verification practices: assessing the use of the WHO-FIND Malaria RDT Evaluation Programme (2011-2014)
Published in Malaria journal (15-05-2017)“…Malaria rapid diagnostic tests (RDTs) play a critical role in malaria case management, and assurance of quality is a key factor to promote good adherence to…”
Get full text
Journal Article -
10
Leishmania major metacaspase can replace yeast metacaspase in programmed cell death and has arginine-specific cysteine peptidase activity
Published in International journal for parasitology (01-02-2007)“…The human protozoan parasite Leishmania major has been shown to exhibit several morphological and biochemical features characteristic of a cell death program…”
Get full text
Journal Article -
11
Development and clinical performance of high throughput loop-mediated isothermal amplification for detection of malaria
Published in PloS one (06-02-2017)“…Accurate and efficient detection of sub-microscopic malaria infections is crucial for enabling rapid treatment and interruption of transmission. Commercially…”
Get full text
Journal Article -
12
Processing of metacaspase into a cytoplasmic catalytic domain mediating cell death in Leishmania major
Published in Molecular microbiology (01-01-2011)“…Summary Metacaspases are cysteine peptidases that could play a role similar to caspases in the cell death programme of plants, fungi and protozoa. The human…”
Get full text
Journal Article -
13
LAMP kit for diagnosis of non-falciparum malaria in Plasmodium ovale infected patients
Published in Malaria journal (07-01-2017)“…Microscopy and rapid diagnosis tests have a limited sensitivity in diagnosis of malaria by Plasmodium ovale. The LAMP kit (LoopAMP®) can be used in the field…”
Get full text
Journal Article -
14
Molecular assays for antimalarial drug resistance surveillance: A target product profile
Published in PloS one (20-09-2018)“…Antimalarial drug resistance is a major constraint for malaria control and elimination efforts. Artemisinin-based combination therapy is now the mainstay for…”
Get full text
Journal Article -
15
Field Evaluation of a High Throughput Loop Mediated Isothermal Amplification Test for the Detection of Asymptomatic Plasmodium Infections in Zanzibar
Published in PloS one (2017)“…New field applicable diagnostic tools are needed for highly sensitive detection of residual malaria infections in pre-elimination settings. Field performance…”
Get full text
Journal Article -
16
Prototype Positive Control Wells for Malaria Rapid Diagnostic Tests: Prospective Evaluation of Implementation Among Health Workers in Lao People's Democratic Republic and Uganda
Published in The American journal of tropical medicine and hygiene (08-02-2017)“…Rapid diagnostic tests (RDTs) are widely used for malaria diagnosis, but lack of quality control at point of care restricts trust in test results. Prototype…”
Get full text
Journal Article -
17
Pan-Plasmodium band sensitivity for Plasmodium falciparum detection in combination malaria rapid diagnostic tests and implications for clinical management
Published in Malaria journal (18-03-2015)“…Malaria rapid diagnostic tests (RDTs) are appropriate for case management, but persistent antigenaemia is a concern for HRP2-detecting RDTs in endemic areas…”
Get full text
Journal Article -
18
The design and evaluation of a shaped filter collection device to sample and store defined volume dried blood spots from finger pricks
Published in Malaria journal (05-02-2015)“…Dried blood spots are a common medium for collecting patient blood prior to testing for malaria by molecular methods. A new shaped filter device for the quick…”
Get full text
Journal Article -
19
Antimicrobial resistance in Africa: a systematic review
Published in BMC infectious diseases (11-09-2017)“…Antimicrobial resistance (AMR) is widely acknowledged as a global problem, yet in many parts of the world its magnitude is still not well understood. This…”
Get full text
Journal Article -
20
The inverted cup device for blood transfer on malaria RDTs: ease of use, acceptability and safety in routine use by health workers in Nigeria
Published in Malaria journal (15-01-2018)“…Malaria rapid diagnostic tests (RDTs) are becoming widely adopted for case management at community level. However, reports and anecdotal observations indicate…”
Get full text
Journal Article