Search Results - "Gonzalez, Gwendolyn"

Identification of YTH Domain-Containing Proteins as the Readers for N1‑Methyladenosine in RNA by Dai, Xiaoxia, Wang, Tianlu, Gonzalez, Gwendolyn, Wang, Yinsheng

“…N1-methyladenosine (m1A) is an important post-transcriptional modification in RNA; however, the exact biological role of m1A remains to be determined. By…”
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ALKBH5 regulates anti–PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment by Li, Na, Kang, Yuqi, Wang, Lingling, Huff, Sarah, Tang, Rachel, Hui, Hui, Agrawal, Kriti, Gonzalez, Gwendolyn Michelle, Wang, Yinsheng, Patel, Sandip Pravin, Rana, Tariq M.

“…Although immune checkpoint blockade (ICB) therapy has revolutionized cancer treatment, many patients do not respond or develop resistance to ICB…”
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Associations of smoking and air pollution with peripheral blood RNA N6-methyladenosine in the Beijing truck driver air pollution study by Kupsco, Allison, Gonzalez, Gwendolyn, Baker, Brennan H., Knox, Julia M., Zheng, Yinan, Wang, Sheng, Chang, Dou, Schwartz, Joel, Hou, Lifang, Wang, Yinsheng, Baccarelli, Andrea A.

“…•Men that smoked had lower total peripheral blood RNA m6A levels than male nonsmokers.•Total blood RNA m6A was positively associated with 8-hour black carbon…”
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m 6 A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells by Huff, Sarah, Tiwari, Shashi Kant, Gonzalez, Gwendolyn M, Wang, Yinsheng, Rana, Tariq M

“…-methyladenosine (m A) has emerged as the most abundant mRNA modification that regulates gene expression in many physiological processes. m A modification in…”
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m6A‑RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells by Huff, Sarah, Tiwari, Shashi Kant, Gonzalez, Gwendolyn M, Wang, Yinsheng, Rana, Tariq M

“…N 6-methyladenosine (m6A) has emerged as the most abundant mRNA modification that regulates gene expression in many physiological processes. m6A modification…”
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Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71 by Kozlova, Elena V., Valdez, Matthew C., Denys, Maximillian E., Bishay, Anthony E., Krum, Julia M., Rabbani, Kayhon M., Carrillo, Valeria, Gonzalez, Gwendolyn M., Lampel, Gregory, Tran, Jasmin D., Vazquez, Brigitte M., Anchondo, Laura M., Uddin, Syed A., Huffman, Nicole M., Monarrez, Eduardo, Olomi, Duraan S., Chinthirla, Bhuvaneswari D., Hartman, Richard E., Kodavanti, Prasada Rao S., Chompre, Gladys, Phillips, Allison L., Stapleton, Heather M., Henkelmann, Bernhard, Schramm, Karl-Werner, Curras-Collazo, Margarita C.

“…Polybrominated diphenyl ethers (PBDEs) are ubiquitous persistent organic pollutants (POPs) that are known neuroendocrine disrupting chemicals with adverse…”
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HIV reprograms host m6Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1 by Zhang, Qiong, Kang, Yuqi, Wang, Shaobo, Gonzalez, Gwendolyn Michelle, Li, Wanyu, Hui, Hui, Wang, Yinsheng, Rana, Tariq M.

“…N 6 ,2′- O -dimethyladenosine (m 6 Am) is an abundant RNA modification located adjacent to the 5′-end of the mRNA 7-methylguanosine (m 7 G) cap structure. m 6…”
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Maternal transfer of environmentally relevant polybrominated diphenyl ethers (PBDEs) produces a diabetic phenotype and disrupts glucoregulatory hormones and hepatic endocannabinoids in adult mouse female offspring by Kozlova, Elena V., Chinthirla, Bhuvaneswari D., Pérez, Pedro A., DiPatrizio, Nicholas V., Argueta, Donovan A., Phillips, Allison L., Stapleton, Heather M., González, Gwendolyn M., Krum, Julia M., Carrillo, Valeria, Bishay, Anthony E., Basappa, Karthik R., Currás-Collazo, Margarita C.

“…Polybrominated diphenyl ethers (PBDEs) are brominated flame retardant chemicals and environmental contaminants with endocrine-disrupting properties that are…”
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METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection by Li, Na, Hui, Hui, Bray, Bill, Gonzalez, Gwendolyn Michelle, Zeller, Mark, Anderson, Kristian G., Knight, Rob, Smith, Davey, Wang, Yinsheng, Carlin, Aaron F., Rana, Tariq M.

“…It is urgent and important to understand the relationship of the widespread severe acute respiratory syndrome coronavirus clade 2 (SARS-CoV-2) with host immune…”
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Normalized retention time for scheduled liquid chromatography-multistage mass spectrometry analysis of epitranscriptomic modifications by Gonzalez, Gwendolyn, Cui, Yuxiang, Wang, Pengcheng, Wang, Yinsheng

“…•First scheduled SRM method for high-throughput analysis of modified ribonucleosides.•Defined normalized retention times (iRT) for modified…”
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Role of PCIF1‐mediated 5′‐cap N6‐methyladeonsine mRNA methylation in colorectal cancer and anti‐PD‐1 immunotherapy by Wang, Lingling, Wu, Lujing, Zhu, Zhouting, Zhang, Qiong, Li, Wanyu, Gonzalez, Gwendolyn Michelle, Wang, Yinsheng, Rana, Tariq M

“…Adenosine N6‐methylation (m6A) and N6,2′‐O‐dimethylation (m6Am) are regulatory modifications of eukaryotic mRNAs. m6Am formation is catalyzed by the methyl…”
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Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells by Lichinchi, Gianluigi, Gao, Shang, Saletore, Yogesh, Gonzalez, Gwendolyn Michelle, Bansal, Vikas, Wang, Yinsheng, Mason, Christopher E, Rana, Tariq M

“…N(6)-methyladenosine (m(6)A) is the most prevalent internal modification of eukaryotic mRNA. Very little is known of the function of m(6)A in the immune system…”
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YTHDF2 Binds to 5‑Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA by Dai, Xiaoxia, Gonzalez, Gwendolyn, Li, Lin, Li, Jie, You, Changjun, Miao, Weili, Hu, Junchi, Fu, Lijuan, Zhao, Yonghui, Li, Ruidong, Li, Lichao, Chen, Xuemei, Xu, Yanhui, Gu, Weifeng, Wang, Yinsheng

“…5-Methylcytosine is found in both DNA and RNA; although its functions in DNA are well established, the exact role of 5-methylcytidine (m5C) in RNA remains…”
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Identification of YTH Domain-Containing Proteins as the Readers for N 1-Methyladenosine in RNA by Dai, Xiaoxia, Wang, Tianlu, Gonzalez, Gwendolyn, Wang, Yinsheng

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m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration by Sun, Yuxiang, Dai, Hui, Dai, Xiaoxia, Yin, Jiekai, Cui, Yuxiang, Liu, Xiaochuan, Gonzalez, Gwendolyn, Yuan, Jun, Tang, Feng, Wang, Nan, Perlegos, Alexandra E., Bonini, Nancy M., Yang, X. William, Gu, Weifeng, Wang, Yinsheng

“…Microsatellite repeat expansions within genes contribute to a number of neurological diseases 1 , 2 . The accumulation of toxic proteins and RNA molecules with…”
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PCIF1-mediated deposition of 5′-cap N6,2′-O-dimethyladenosine in ACE2 and TMPRSS2 mRNA regulates susceptibility to SARS-CoV-2 infection by Wang, Lingling, Wang, Shaobo, Wu, Lujing, Li, Wanyu, Bray, William, Clark, Alex E, Gonzalez, Gwendolyn Michelle, Wang, Yinsheng, Carlin, Aaron F, Rana, Tariq M

“…Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be a major health problem worldwide. Due to the fast emergence of…”
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Adenylate Kinase 4 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an m6A-Based Epitranscriptomic Mechanism by Liu, Xiaochuan, Gonzalez, Gwendolyn, Dai, Xiaoxia, Miao, Weili, Yuan, Jun, Huang, Ming, Bade, David, Li, Lin, Sun, Yuxiang, Wang, Yinsheng

“…N6-methyladenosine (m6A) is the most abundant internal modification in mRNA and this methylation constitutes an important regulatory mechanism for the…”
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PCIF1-mediated deposition of 5'-cap N 6 ,2'- O -dimethyladenosine in ACE2 and TMPRSS2 mRNA regulates susceptibility to SARS-CoV-2 infection by Wang, Lingling, Wang, Shaobo, Wu, Lujing, Li, Wanyu, Bray, William, Clark, Alex E, Gonzalez, Gwendolyn Michelle, Wang, Yinsheng, Carlin, Aaron F, Rana, Tariq M

“…Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be a major health problem worldwide. Due to the fast emergence of…”
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Publisher Correction: m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration by Sun, Yuxiang, Dai, Hui, Dai, Xiaoxia, Yin, Jiekai, Cui, Yuxiang, Liu, Xiaochuan, Gonzalez, Gwendolyn, Yuan, Jun, Tang, Feng, Wang, Nan, Perlegos, Alexandra E., Bonini, Nancy M., Yang, X. William, Gu, Weifeng, Wang, Yinsheng

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Dysregulation of Hypothalamic Gene Expression and the Oxytocinergic System by Soybean Oil Diets in Male Mice by Deol, Poonamjot, Kozlova, Elena, Valdez, Matthew, Ho, Catherine, Yang, Ei-Wen, Richardson, Holly, Gonzalez, Gwendolyn, Truong, Edward, Reid, Jack, Valdez, Joseph, Deans, Jonathan R, Martinez-Lomeli, Jose, Evans, Jane R, Jiang, Tao, Sladek, Frances M, Curras-Collazo, Margarita C

“…Abstract Soybean oil consumption has increased greatly in the past half-century and is linked to obesity and diabetes. To test the hypothesis that soybean oil…”
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