Search Results - "Gonzalez, FJ"

PPARα activation is essential for HCV core protein–induced hepatic steatosis and hepatocellular carcinoma in mice by Tanaka, Naoki, Moriya, Kyoji, Kiyosawa, Kendo, Koike, Kazuhiko, Gonzalez, Frank J, Aoyama, Toshifumi

“…Transgenic mice expressing HCV core protein develop hepatic steatosis and hepatocellular carcinoma (HCC), but the mechanism underlying this process remains…”
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Polyenephosphatidylcholine prevents alcoholic liver disease in PPARα-null mice through attenuation of increases in oxidative stress by Okiyama, Wataru, Tanaka, Naoki, Nakajima, Tamie, Tanaka, Eiji, Kiyosawa, Kendo, Gonzalez, Frank J, Aoyama, Toshifumi

“…Background/Aims Alcoholic liver disease (ALD) is one of the leading causes of cirrhosis and yet efficient therapeutic strategies are lacking…”
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Key Issues in Hymenoptera Venom Allergy: An Update by Alfaya Arias, T, Soriano Gómis, V, Soto Mera, T, Vega Castro, A, Vega Gutiérrez, J M, Alonso Llamazares, A, Antolín Amérigo, D, Carballada Gonzalez, F J, Dominguez Noche, C, Gutierrez Fernandez, D, Marques Amat, L, Martinez Arcediano, A, Martinez San Ireneo, M, Moreno Ancillo, A, Puente Crespo, Y, Ruiz Leon, B, Sánchez Morillas, L

“…In this review, the Hymenoptera Allergy Committee of the SEAIC analyzes the most recent scientific literature addressing problems related to the diagnosis of…”
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FYDATA STUDY: PERAMPANEL STUDY IN A REAL-LIFE SETTING by Villanueva, V, Garces, M, Gonzalez, FJ López, Rodriguez-Osorio, X, Uranga, JJ Rodriguez, López-Gomáriz, E, Montoya, J, Aldea, JJ Poza, Molins, A, Saiz-Diaz, R, Aleja, J González de la, Mauri, J Angel, Castillo, A, Picho, FJ Lopez-Trigo, Toledo, M, Puig, J Salas, Blance, D Campos, Flores, J

“…FYDATA is a multi-centre, retrospective, 1-year, observational study (inclusion criteria: written informed consent to review clinical charts; patients ≥12…”
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Enhanced Acetaminophen Toxicity by Activation of the Pregnane X Receptor by Guo, Grace L., Moffit, Jeff S., Nicol, Christopher J., Ward, Jerrold M., Aleksunes, Lauren A., Slitt, Angela L., Kliewer, Steven A., Manautou, Jose E., Gonzalez, Frank J.

“…The pregnane X receptor (PXR) is a ligand-activated transcription factor and member of the nuclear receptor superfamily. Activation of PXR represents an…”
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Transcription Coactivator Peroxisome Proliferator-Activated Receptor-Binding Protein/Mediator 1 Deficiency Abrogates Acetaminophen Hepatotoxicity by Jia, Yuzhi, Guo, Grace L., Surapureddi, Sailesh, Sarkar, Joy, Qi, Chao, Guo, Dongsheng, Xia, Jun, Kashireddi, Papreddy, Yu, Songtao, Cho, Young-Wook, Rao, M. Sambasiva, Kemper, Byron, Ge, Kai, Gonzalez, Frank J., Reddy, Janardan K., Hammock, Bruce D.

“…Peroxisome proliferator-activated receptor-binding protein (PBP), also known as thyroid hormone receptor-associated protein 220/vitamin D receptor-interacting…”
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Cholesterol-lowering effect of bezafibrate is independent of peroxisome proliferator-activated receptor activation in mice by Nakajima, Takero, Tanaka, Naoki, Sugiyama, Eiko, Kamijo, Yuji, Hara, Atsushi, Hu, Rui, Li, Gang, Li, Yufeng, Nakamura, Kozo, Gonzalez, Frank J., Aoyama, Toshifumi

“…The hypocholesterolemic potential of peroxisome proliferator-activated receptor (PPAR) pan-activator bezafibrate has been documented. However, in addition to…”
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Constitutive expression of hepatic cytochrome P450 genes by Gonzalez, F J, Lee, Y H

“…Cytochromes P450 are a superfamily of heme proteins involved in oxidative metabolism of endogenous chemicals such as steroid hormones and human-made…”
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Virtual reality for acute pain in outpatient hysteroscopy: a randomised controlled trial by Deo, N, Khan, KS, Mak, J, Allotey, J, Gonzalez Carreras, FJ, Fusari, G, Benn, J

“…Objective To evaluate the effectiveness of virtual reality as a distraction technique in the management of acute pain and anxiety during outpatient…”
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Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions by Rettie, Allan E, Korzekwa, Kenneth R, Kunze, Kent L, Lawrence, Ross F, Eddy, A Craig, Aoyama, Toshifumi, Gelboin, Harry V, Gonzalez, Frank J, Trager, William F

“…Previous kinetic studies have identified a high-affinity (S)-warfarin 7-hydroxylase present in human liver microsomes which appears to be responsible for the…”
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Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone by SHOU, M, KORZEKWA, K. R, BROOKS, E. N, KRAUSZ, K. W, GONZALEZ, F. J, GELBOIN, H. V

“…The metabolic activation of estrone (E1), a potent estrogen was investigated using recombinant human cytochrome P450 enzymes, 1A2, 2B6, 2C8, 2C9, 2C9R144C,…”
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Pregnane X receptor as a target for treatment of inflammatory bowel disorders by Cheng, Jie, Shah, Yatrik M, Gonzalez, Frank J

“…Pregnane X receptor (PXR; NR1I2), a member of the nuclear receptor superfamily, has a major role in the induction of genes involved in drug transport and…”
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Lidocaine metabolism in human liver microsomes by cytochrome P450IIIA4 by Bargetzi, M J, Aoyama, T, Gonzalez, F J, Meyer, U A

“…The metabolism of lidocaine to its major metabolite monoethylglycinexylidide (MEGX) was studied in human liver microsomes of 13 kidney transplant donors and of…”
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CO146 Treatment Use and Overall Survival of Patients with Unresectable/Metastatic Melanoma in Colombia: A Real World Study by Reyes, Sanchez JM, Bolaños-López, J.., Bello, C., Rubio, AC, Gonzalez, FJ, Toro, A., Chen, K., Arciniegas, J., Alarcon, B.A.., Garcia, M.

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EPH22 Epidemiology and Treatment Patterns of Colombian Patients With Metastatic Colorectal by Bolaños-López, J., Bello, C, Reyes, Sanchez JM, Olaya, V, Gonzalez, FJ, Arciniegas, J, Garcia, M, Alarcon, B.A., Vieira, MC

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EPH211 Treatment Patterns and Clinical Characteristics of Patients Diagnosed with Metastatic NSCLC in Hmo from Colombia: A Real Word Evidence Study by Gonzalez, FJ, Perez, LE, Bello, C, Reyes, Sanchez JM, Bolaños-López, J, Pardo, S, Arciniegas, J, Garcia, M, Idrobo, H

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CO65 Overall Survival in Metastatic NSCLC in HMO From Colombia: A Non-Interventional Study by Reyes, Sanchez JM, Perez, LE, Bolaños-López, J.., Bello, C., Gonzalez, FJ, Idrobo, H., Arciniegas, J., Garcia, M., Pardo, S.

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EPH205 Frequency of Moderate to Severe Atopic Dermatitis and Clinical Characteristics in a Colombian HMO: Results for 2015-2022 by Gonzalez, FJ, Reyes, Sanchez JM, Bolaños-López, J, Arciniegas, J, Bello, C, Garcia, M, Amador, L, Toro, A

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Evaluation of the seismic rock mass response to mining and the impact of preconditioning using an epidemic-type aftershock model by Gonzalez, F.J., Vallejos, J.A., Rojas, E., Landeros, P.

“…Preconditioning techniques are frequently used to reduce the seismic hazard induced by mining under high-stress conditions. However, the impact of…”
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An evaluation of multidrug-resistant Escherichia coli isolates in urinary tract infections from Aguascalientes, Mexico: cross-sectional study by Ramírez-Castillo, Flor Y, Moreno-Flores, Adriana C, Avelar-González, Francisco J, Márquez-Díaz, Francisco, Harel, Josée, Guerrero-Barrera, Alma L

“…Uropathogenic Escherichia coli (UPEC) are one of the main bacteria causing urinary tract infections (UTIs). The rates of UPEC with high resistance towards…”
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