Search Results - "Gonzalez, Cassandra L"
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Cdkn2a suppresses metastasis in squamous cell carcinomas induced by the gain-of-function mutant p53(R172H)
Published in The Journal of pathology (01-10-2016)“…p53 (TP53) is the most frequently mutated gene in squamous cell carcinomas (SCCs) of the skin and head and neck. Certain p53 mutations are oncogenic and…”
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Journal Article -
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Epithelial Mutant p53 Promotes Resistance to Anti-PD-1-Mediated Oral Cancer Immunoprevention in Carcinogen-Induced Mouse Models
Published in Cancers (23-03-2021)“…Oral squamous cell carcinoma (OSCC) develops through the multistep malignant progression of squamous epithelium. This process can be prevented by PD-1 blockade…”
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Journal Article -
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Cdkn2a suppresses metastasis in squamous cell carcinomas induced by the gain-of-function mutant p53R172H
Published in The Journal of pathology (01-10-2016)“…p53 (TP53) is the most frequently mutated gene in squamous cell carcinomas (SCCs) of the skin and head and neck. Certain p53 mutations are oncogenic and…”
Get full text
Journal Article -
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Cdkn2a suppresses metastasis in squamous cell carcinomas induced by the gain-of-function mutant p53 super(R172H)
Published in The Journal of pathology (01-10-2016)“…p53 ( TP53 ) is the most frequently mutated gene in squamous cell carcinomas (SCCs) of the skin and head and neck. Certain p53 mutations are oncogenic and…”
Get full text
Journal Article -
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Loss of epithelial p53 and αv integrin cooperate through Akt to induce squamous cell carcinoma yet prevent remodeling of the tumor microenvironment
Published in Oncogene (22-01-2015)“…Most of the squamous cell carcinomas (SCCs) of the skin and head and neck contain p53 mutations. The presence of p53 mutations in premalignant lesions suggests…”
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Journal Article