Search Results - "Gonzalez, Barbara"
-
1
A transcriptional switch governs fibroblast activation in heart disease
Published in Nature (London) (15-07-2021)“…In diseased organs, stress-activated signalling cascades alter chromatin, thereby triggering maladaptive cell state transitions. Fibroblast activation is a…”
Get full text
Journal Article -
2
Using the LSAT as a labor market thermometer for lawyers
Published in The American journal of economics and sociology (01-01-2023)“…We rely upon a 50‐state, 20‐year panel to find that the number of Law School Admissions Test (LSAT) takers is only loosely related to economic…”
Get full text
Journal Article -
3
Academic achievement and gender among adult critical care program directors
Published in Journal of critical care (01-06-2021)“…Accreditation Council for Graduate Medical Education (ACGME) program director (PD) qualifications includes scholarly activity with demonstrated academic…”
Get full text
Journal Article -
4
Behavioral effects of the combined use of alcohol and energy drinks on alcohol hangover in an experimental mice model
Published in Neuroscience letters (23-03-2018)“…•Mixing alcohol and energy drinks is common practice among young people.•Neuromuscular coordination and muscle strength were affected by the mixture.•The…”
Get full text
Journal Article -
5
p38γ and δ promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradation
Published in Nature communications (22-01-2016)“…Disrupted organ growth leads to disease development. Hypertrophy underlies postnatal heart growth and is triggered after stress, but the molecular mechanisms…”
Get full text
Journal Article -
6
Hepatic p63 regulates steatosis via IKKβ/ER stress
Published in Nature communications (08-05-2017)“…p53 family members control several metabolic and cellular functions. The p53 ortholog p63 modulates cellular adaptations to stress and has a major role in cell…”
Get full text
Journal Article -
7
The naturally‐derived alkaloids as a potential treatment for COVID‐19: A scoping review
Published in Phytotherapy research (01-07-2022)“…Coronavirus disease 2019 (COVID‐19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2), which has a high mortality rate and…”
Get full text
Journal Article -
8
p38γ and p38δ reprogram liver metabolism by modulating neutrophil infiltration
Published in The EMBO journal (01-03-2016)“…Non‐alcoholic fatty liver disease (NAFLD) is a major health problem and the main cause of liver disease in Western countries. Although NAFLD is strongly…”
Get full text
Journal Article -
9
Effects of Salmonella enterica serovar Enteritidis on cellular recruitment and cytokine gene expression in caecum of vaccinated chickens
Published in Vaccine (03-10-2008)“…Abstract Although vaccination of poultry is a suitable method to limit human food borne gastroenteritis caused by Salmonella ( S .), the immune mechanisms…”
Get full text
Journal Article -
10
Differential activation of p38MAPK isoforms by MKK6 and MKK3
Published in Cellular signalling (01-04-2010)“…All four members of the mammalian p38 mitogen-activated protein kinase (MAPK) family (p38α, p38β, p38γ and p38δ) are activated by dual phosphorylation in the…”
Get full text
Journal Article -
11
Marine bacteria associated with shallow hydrothermal systems in the Gulf of California with the capacity to produce biofilm inhibiting compounds
Published in Archives of microbiology (01-08-2020)“…Shallow hydrothermal systems are extreme environments. The sediments and fluids emitted from the vents present unusual physical and chemical conditions…”
Get full text
Journal Article -
12
Melatonin Attenuates Dysregulation of the Circadian Clock Pathway in Mice With CCl4-Induced Fibrosis and Human Hepatic Stellate Cells
Published in Frontiers in pharmacology (28-05-2018)“…Dysregulation of the circadian clock machinery is a critical mechanism in the pathogenesis of fibrosis. This study aimed to investigate whether the…”
Get full text
Journal Article -
13
Medical specialization in Chile. A centralized vision
Published in Revista medíca de Chile (01-11-2017)“…Medical graduates face different postgraduate training options, but their priority is to obtain a primary medical specialty, defined as a specialty that does…”
Get full text
Journal Article -
14
Sphingosine 1-Phosphate Signaling as a Target in Hepatic Fibrosis Therapy
Published in Frontiers in pharmacology (25-08-2017)“…Liver fibrosis is an excess production of extracellular matrix proteins as a result of chronic liver disease which leads to cell death and organ dysfunction…”
Get full text
Journal Article -
15
Sex bias in celiac disease: XWAS and monocyte eQTLs in women identify TMEM187 as a functional candidate gene
Published in Biology of sex differences (11-12-2023)“…Celiac disease (CeD) is an immune-mediated disorder that develops in genetically predisposed individuals upon gluten consumption. HLA risk alleles explain 40%…”
Get full text
Journal Article -
16
Non-contrast transoesophageal echo-guided transapical transcatheter aortic valve replacement: 10-year experience of a renoprotective strategy
Published in Interactive cardiovascular and thoracic surgery (26-07-2021)“…Abstract OBJECTIVES This study aims to evaluate the efficacy, safety and long-term outcomes of a renoprotective non-contrast, transoesophageal…”
Get full text
Journal Article -
17
Protocol for a pilot and feasibility randomized-controlled trial of four weeks of oral γ-aminobutyric acid (GABA) intake and its effect on pain and sleep in middle-to-older aged adults
Published in Contemporary clinical trials communications (01-04-2023)“…Approximately 1.71 billion people globally live with musculoskeletal pain conditions, including low back pain, knee pain, and neck pain Cieza et al. (2020). In…”
Get full text
Journal Article -
18
Safety of a proteoliposome from Neisseria meningitides as adjuvant for a house dust mite allergy vaccine
Published in Journal of immunotoxicology (01-01-2017)“…The proteoliposome (PL) of Neisseria meningitidis serogroup B has been reported as a safe and potent vaccine adjuvant, inducing a T H 1-skewed response. The…”
Get full text
Journal Article -
19
Transcription factor protein interactomes reveal genetic determinants in heart disease
Published in Cell (03-03-2022)“…Congenital heart disease (CHD) is present in 1% of live births, yet identification of causal mutations remains challenging. We hypothesized that genetic…”
Get full text
Journal Article -
20
Metal-Organic Frameworks for Dual Photo-Oxidation and Capture of Arsenic from Water
Published in ChemSusChem (08-08-2024)“…Despite rapid technological progress, heavy metal water pollution, and particularly arsenic contamination, remains a significant global challenge. In addition,…”
Get full text
Journal Article