Search Results - "Gonzalez, Anjelica L."

Extracellular Mitochondrial DNA Is Generated by Fibroblasts and Predicts Death in Idiopathic Pulmonary Fibrosis by Ryu, Changwan, Sun, Huanxing, Gulati, Mridu, Herazo-Maya, Jose D, Chen, Yonglin, Osafo-Addo, Awo, Brandsdorfer, Caitlin, Winkler, Julia, Blaul, Christina, Faunce, Jaden, Pan, Hongyi, Woolard, Tony, Tzouvelekis, Argyrios, Antin-Ozerkis, Danielle E, Puchalski, Jonathan T, Slade, Martin, Gonzalez, Anjelica L, Bogenhagen, Daniel F, Kirillov, Varvara, Feghali-Bostwick, Carol, Gibson, Kevin, Lindell, Kathleen, Herzog, Raimund I, Dela Cruz, Charles S, Mehal, Wajahat, Kaminski, Naftali, Herzog, Erica L, Trujillo, Glenda

“…Idiopathic pulmonary fibrosis (IPF) involves the accumulation of α-smooth muscle actin-expressing myofibroblasts arising from interactions with soluble…”
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Biomimetic, ultrathin and elastic hydrogels regulate human neutrophil extravasation across endothelial-pericyte bilayers by Lauridsen, Holly M, Gonzalez, Anjelica L

“…The vascular basement membrane-a thin, elastic layer of extracellular matrix separating and encasing vascular cells-provides biological and mechanical cues to…”
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Endothelial cell secreted VEGF-C enhances NSC VEGFR3 expression and promotes NSC survival by Matta, Rita, Feng, Yan, Sansing, Lauren H., Gonzalez, Anjelica L.

“…[Display omitted] •EC promote NSC survival during GD via cell–cell contact and soluble factor secretion.•EC secreted VEGF-C enhances NSC survival and NSC…”
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Netrin‐1 Regulates Fibrocyte Accumulation in the Decellularized Fibrotic Sclerodermatous Lung Microenvironment and in Bleomycin‐Induced Pulmonary Fibrosis by Sun, Huanxing, Zhu, Yangyang, Pan, Hongyi, Chen, Xiaosong, Balestrini, Jenna L., Lam, TuKiet T., Kanyo, Jean E., Eichmann, Anne, Gulati, Mridu, Fares, Wassim H., Bai, Hanwen, Feghali‐Bostwick, Carol A., Gan, Ye, Peng, Xueyan, Moore, Meagan W., White, Eric S., Sava, Parid, Gonzalez, Anjelica L., Cheng, Yuwei, Niklason, Laura E., Herzog, Erica L.

“…Objective Fibrocytes are collagen‐producing leukocytes that accumulate in patients with systemic sclerosis (SSc; scleroderma)–related interstitial lung disease…”
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Transendothelial migration enables subsequent transmigration of neutrophils through underlying pericytes by Ayres-Sander, Chantal E, Lauridsen, Holly, Maier, Cheryl L, Sava, Parid, Pober, Jordan S, Gonzalez, Anjelica L

“…During acute inflammation, neutrophil recruitment into extravascular tissue requires neutrophil tethering and rolling on cytokine-activated endothelial cells…”
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Daily egg consumption in hyperlipidemic adults--effects on endothelial function and cardiovascular risk by Njike, Valentine, Faridi, Zubaida, Dutta, Suparna, Gonzalez-Simon, Anjelica L, Katz, David L

“…Limiting consumption of eggs, which are high in cholesterol, is generally recommended to reduce risk of cardiovascular disease. However, recent evidence…”
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Endothelial cell secreted metalloproteinase‐2 enhances neural stem cell N‐cadherin expression, clustering, and migration by Matta, Rita, Yousafzai, Muhammad Sulaiman, Murrell, Michael, Gonzalez, Anjelica L.

“…Neuroblasts have a clustered phenotype critical for their unidirectional migration, which in part is dependent on signaling from microvascular endothelial…”
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ECM hydrogel improves the delivery of PEG microsphere-encapsulated neural stem cells and endothelial cells into tissue cavities caused by stroke by Ghuman, Harmanvir, Matta, Rita, Tompkins, Alexandra, Nitzsche, Franziska, Badylak, Stephen F., Gonzalez, Anjelica L., Modo, Michel

“…[Display omitted] •Assembly of neural stem cells and endothelial cells in an implantable microsphere.•Biomechanical characterization of implantation procedure…”
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TGF-β1 Drives Integrin-Dependent Pericyte Migration and Microvascular Destabilization in Fibrotic Disease by Pellowe, Amanda S., Wu, Michelle J., Kang, Tae-Yun, Chung, Tracy D., Ledesma-Mendoza, Adrian, Herzog, Erica, Levchenko, Andre, Odell, Ian, Varga, John, Gonzalez, Anjelica L.

“…Interactions between endothelial cells (ECs) and mural pericytes (PCs) are critical in maintaining the stability and function of the microvascular wall…”
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IL-17 Promotes Neutrophil-Mediated Immunity by Activating Microvascular Pericytes and Not Endothelium by Liu, Rebecca, Lauridsen, Holly M, Amezquita, Robert A, Pierce, Richard W, Jane-Wit, Dan, Fang, Caodi, Pellowe, Amanda S, Kirkiles-Smith, Nancy C, Gonzalez, Anjelica L, Pober, Jordan S

“…A classical hallmark of acute inflammation is neutrophil infiltration of tissues, a multistep process that involves sequential cell-cell interactions of…”
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Transendothelial migration enhances integrin-dependent human neutrophil chemokinesis by Gonzalez, Anjelica L., El‐Bjeirami, Wafa, West, Jennifer L., McIntire, Larry V., Smith, C. Wayne

“…Transendothelial migration of neutrophils induces phenotypic changes that influence the interactions of neutrophils with extravascular tissue components. To…”
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Human pericytes adopt myofibroblast properties in the microenvironment of the IPF lung by Sava, Parid, Ramanathan, Anand, Dobronyi, Amelia, Peng, Xueyan, Sun, Huanxing, Ledesma-Mendoza, Adrian, Herzog, Erica L, Gonzalez, Anjelica L

“…Idiopathic pulmonary fibrosis (IPF) is a fatal disease of unknown etiology characterized by a compositionally and mechanically altered extracellular matrix…”
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Endothelial cell‐secreted MIF reduces pericyte contractility and enhances neutrophil extravasation by Pellowe, Amanda S., Sauler, Maor, Hou, Yue, Merola, Jonathan, Liu, Rebecca, Calderon, Brenda, Lauridsen, Holly M., Harris, Mariah R., Leng, Lin, Zhang, Yi, Tilstam, Pathricia V., Pober, Jordan S., Bucala, Richard, Lee, Patty J., Gonzalez, Anjelica L.

“…ABSTRACT Dysregulated neutrophil extravasation contributes to the pathogenesis of many inflammatory disorders. Pericytes (PCs) have been implicated in the…”
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Tumor Necrosis Factor-α and IL-17A Activation Induces Pericyte-Mediated Basement Membrane Remodeling in Human Neutrophilic Dermatoses by Lauridsen, Holly M, Pellowe, Amanda S, Ramanathan, Anand, Liu, Rebecca, Miller-Jensen, Kathryn, McNiff, Jennifer M, Pober, Jordan S, Gonzalez, Anjelica L

“…Sweet syndrome is a prototypical neutrophilic dermatosis, a class of inflammatory diseases marked by elevated levels of tumor necrosis factor (TNF)-α and…”
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Engineered Biomimetic Neural Stem Cell Niche by Matta, Rita, Gonzalez, Anjelica L.

“…Purpose of Review Neural stem cells (NSCs) have the potential to proliferate and differentiate into functional neurons, heightening their potential use for…”
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Minimally Invasive Delivery of Microbeads with Encapsulated, Viable and Quiescent Neural Stem Cells to the Adult Subventricular Zone by Matta, Rita, Lee, Seyoung, Genet, Nafiisha, Hirschi, Karen K., Thomas, Jean-Leon, Gonzalez, Anjelica L.

“…Stem cell therapies demonstrate promising results as treatment for neurological disease and injury, owing to their innate ability to enhance endogenous neural…”
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Author Correction: Minimally Invasive Delivery of Microbeads with Encapsulated, Viable and Quiescent Neural Stem Cells to the Adult Subventricular Zone by Matta, Rita, Lee, Seyoung, Genet, Nafiisha, Hirschi, Karen K., Thomas, Jean-Leon, Gonzalez, Anjelica L.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Human Microvascular Pericyte Basement Membrane Remodeling Regulates Neutrophil Recruitment by Sava, Parid, Cook, Ian O., Mahal, Rajwant S., Gonzalez, Anjelica L.

“…Objective Neutrophil extravasation at post‐capillary venules, consisting of EC, PC, and the shared ECM, increases following fibrotic remodeling in the lung,…”
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Engineering multicellular living systems—a Keystone Symposia report by Cable, Jennifer, Arlotta, Paola, Parker, Kevin Kit, Hughes, Alex J., Goodwin, Katharine, Mummery, Christine L., Kamm, Roger D., Engle, Sandra J., Tagle, Danilo A., Boj, Sylvia F., Stanton, Alice E., Morishita, Yoshihiro, Kemp, Melissa L., Norfleet, Dennis A., May, Elebeoba E., Lu, Aric, Bashir, Rashid, Feinberg, Adam W., Hull, Sarah M., Gonzalez, Anjelica L., Blatchley, Michael R., Montserrat Pulido, Núria, Morizane, Ryuji, McDevitt, Todd C., Mishra, Deepak, Mulero‐Russe, Adriana

“…The ability to engineer complex multicellular systems has enormous potential to inform our understanding of biological processes and disease and alter the drug…”
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Extracellular matrix biomimicry for the creation of investigational and therapeutic devices by Pellowe, Amanda S., Gonzalez, Anjelica L.

“…The extracellular matrix (ECM) is a web of fibrous proteins that serves as a scaffold for tissues and organs, and is important for maintaining homeostasis and…”
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